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1. ACE: Encodes the Angiotensin-Converting Enzyme, involved in blood pressure regulation and cardiovascular functions.
2. APOA2: Encodes Apolipoprotein A-II, a component of high-density lipoprotein (HDL) and influences lipid metabolism and obesity.
3. MCM6: Encodes a protein crucial for DNA replication. SNPs near MCM6 affect lactase persistence.
4. HLA-DQ2.5 & HLA-DQ8: Encode proteins involved in the immune system, specifically related to celiac disease risk.
5. TAS1R3: Encodes a taste receptor that detects sweet and umami flavors.
6. TAS2R38: Encodes a bitter taste receptor, associated with the ability to taste certain bitter compounds.
7. GNB3: Encodes a subunit of G proteins, influencing signal transduction in various physiological processes, including hypertension.
8. BCOM1: Encodes Beta-Carotene Oxygenase 1, involved in vitamin A metabolism.
9. TCN1: Encodes Transcobalamin I, a protein that binds vitamin B12 and is involved in its transport.
10. MTHFR: Encodes Methylenetetrahydrofolate Reductase, involved in folate metabolism and related to cardiovascular and neurological health.
11. SLC23A1 & SLC23A2: Encode transporters involved in the absorption of vitamin C.
12. GC: Encodes the Vitamin D-Binding Protein, crucial for vitamin D transport and metabolism.
13. CYP2R1: Encodes a key enzyme in the activation of vitamin D.
14. TRPM6: Encodes a magnesium transporter, important for magnesium homeostasis and absorption.
15. SEP-15: Encodes a selenoprotein involved in antioxidant defense mechanisms.
16. CA1: Encodes Carbonic Anhydrase I, an enzyme involved in pH regulation and ion transport.
17. LRP5: Encodes a protein involved in bone formation and density, related to osteoporosis risk.
18. FADS1 & FADS2: Encode enzymes involved in the metabolism of polyunsaturated fatty acids, affecting lipid levels and inflammation.
19. MSTN: Encodes Myostatin, a protein that inhibits muscle growth.
20. ACTN3: Encodes Alpha-Actinin-3, a protein related to muscle fiber type and athletic performance.
21. AGTR2: Encodes the Angiotensin II Receptor Type 2, involved in blood pressure regulation and cardiovascular functions.
22. IL-6: Encodes Interleukin-6, a cytokine involved in inflammation and immune response.
23. COL5A1: Encodes a collagen protein involved in connective tissue structure, related to joint and tendon health.
24. CKM: Encodes Creatine Kinase, Muscle type, important for energy metabolism in muscles.
25. FTO: Encodes a protein associated with fat mass and obesity risk.
26. MC4R: Encodes the Melanocortin 4 Receptor, involved in appetite regulation and energy balance.
27. SLC30A8: Encodes a zinc transporter, linked to insulin secretion and diabetes risk.
28. TCF7L2: Encodes a transcription factor involved in glucose metabolism and type 2 diabetes risk.
29. ADD1: Encodes Adducin 1, involved in cytoskeleton organization and linked to blood pressure regulation.
30. LDLR: Encodes the Low-Density Lipoprotein Receptor, crucial for cholesterol metabolism and cardiovascular disease risk.
31. APOB: Encodes Apolipoprotein B, a primary component of low-density lipoproteins (LDL), involved in cholesterol transport.
32. CYP1A2: Encodes a liver enzyme that metabolizes caffeine and other substances, affecting drug metabolism.
33. ADORA2A: Encodes the Adenosine A2A Receptor, involved in the regulation of sleep, pain, and inflammation.
34. CLOCK: Encodes a protein that regulates circadian rhythms and influences sleep-wake cycles.
35. GABRA6: Encodes a subunit of the GABA-A receptor, involved in neurotransmission and related to anxiety and stress responses.
36. HTR1B: Encodes the 5-HT1B serotonin receptor, involved in neurotransmission and mood regulation.
37. NPAS2: Encodes a transcription factor involved in the regulation of circadian rhythms and sleep-wake cycles.
These genes play significant roles in various physiological processes, from metabolism and cardiovascular health to muscle function and circadian rhythms. Understanding these genes can provide insights into individual health risks, dietary needs, and response to exercise.
Understanding your genetic makeup can significantly enhance your quality of life. At London Blood Tests, we offer a comprehensive and reliable Nutrition and Lifestyle DNA Test to help you make informed decisions about your diet, exercise, and overall lifestyle. Book your test today and take the first step towards a healthier, more personalized approach to wellness.
Our tailored tests will help you discover health insights to assess your wellbeing.
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