*Home-visit for extra £60.
Our Genetic Breast & Ovarian Cancer Risk Test screens and detects genetic variants in 8 genes that may increase the risk of breast and ovarian cancer. The genes analyzed include ATM, BRCA1, BRCA2, CDH1, CHEK2, PALB2, PTEN, and TP53.
1. ATM: Involved in DNA repair. Mutations increase the risk of breast cancer and other cancers.
2. BRCA1: Helps repair damaged DNA. Mutations greatly increase the risk of breast and ovarian cancer.
3. BRCA2: Similar to BRCA1, involved in DNA repair. Mutations also significantly increase the risk of breast and ovarian cancer.
4. CDH1: Encodes a protein that helps cells stick together. Mutations are linked to an increased risk of hereditary diffuse gastric cancer and lobular breast cancer.
5. CHEK2: Encodes a protein involved in DNA damage response. Mutations can increase the risk of breast cancer and other types of cancer.
6. PALB2: Works with BRCA2 in DNA repair. Mutations increase the risk of breast cancer.
7. PTEN: A tumor suppressor gene that regulates cell growth. Mutations cause Cowden syndrome, which increases the risk of breast, thyroid, and other cancers.
8. TP53: Encodes the p53 protein, a key tumor suppressor that prevents cancer. Mutations are associated with Li-Fraumeni syndrome, which greatly increases the risk of various cancers, including breast cancer.
• Individuals diagnosed with breast or ovarian cancer.
• Those with a family history of breast or ovarian cancer.
• Anyone seeking to understand their genetic risk for breast and ovarian cancer.
Our tailored tests will help you discover health insights to assess your wellbeing.
Accreditation
London Medical Laboratory is registered with and regulated by the Care Quality Commission.
Certificate number: CRT1-4708702735
London Medical Laboratory is accredited in accordance with International
Standard ISO 15189:2012
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