About the Genetic Lactose Intolerance Test

At the core of our Genetic Lactose Intolerance Test are Single Nucleotide Polymorphisms, or SNPs, critical indicators in genetic testing. This test specifically targets two SNPs in the MCM6 gene: C13910T and G22018A. These markers provide insights into lactase persistence, the ability of adults to digest lactose—a sugar found predominantly in dairy products.

· C13910T: This SNP involves a change where a Cytosine (C) is replaced by a Thymine (T) at position 13910 of the DNA sequence. The presence of T at this position is strongly associated with lactase persistence, allowing individuals to continue digesting lactose into adulthood.

· G22018A: Similarly, this SNP represents a change from Guanine (G) to Adenine (A) at position 22018. This variation can also influence lactase persistence, alongside other genetic traits, contributing to a broader understanding of your genetic predispositions.

The MCM6 gene, which houses these SNPs, is situated near the LCT gene that encodes the enzyme lactase. The activity of the LCT gene—and thereby the body's ability to process lactose—is regulated by the configuration of these SNPs. Through our test, you gain essential genetic insights, empowering you to tailor your diet according to your genetic ability to metabolise lactose.

Who Should Consider This Test?

The Genetic Lactose Intolerance Test is particularly beneficial for individuals who experience symptoms that may suggest lactose intolerance. These symptoms can include bloating, abdominal pain, gas, diarrhoea, or nausea after consuming dairy products. If you've noticed these reactions and are unsure about the cause, this test can provide definitive genetic insights into your body's ability to digest lactose.

Additionally, this test is a valuable resource for anyone interested in personalised health and nutrition. Understanding your genetic predisposition to lactose intolerance can help you make more informed choices about your diet, potentially improving gastrointestinal comfort and overall well-being.

Parents considering dietary choices for their children, especially when introducing dairy into their diets, may also find this test instrumental. Knowing whether a child has a genetic predisposition to lactose intolerance can guide nutritional decisions that support healthier development.

Finally, health enthusiasts and those involved in dietary planning who wish to optimise their nutritional intake can benefit from the insights provided by this test. It allows for a more tailored approach to diet that considers one's unique genetic makeup, enhancing personal health management.

What to Expect From the Test

Opting for the Genetic Lactose Intolerance Test with London Blood Tests is a straightforward and informative process. Here’s what you can expect:

Step 1: Booking and Sample Collection

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• • To initiate the testing process, simply book an appointment through our website or contact our customer service. We provide at-home testing kits, which means you can collect your DNA sample in the comfort and privacy of your own home.
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• • The kit typically includes a saliva collection tube; detailed instructions will guide you on how to collect your sample effectively.

Step 2: Sending Your Sample

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• • Once you’ve collected your saliva sample, send it back to our lab using the pre-paid envelope included in your kit. Our state-of-the-art facilities will handle your sample with the utmost care and precision.

Step 3: Analysis and Results

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• • Our expert geneticists analyse your sample for the C13910T and G22018A SNPs in the MCM6 gene. The testing process employs the latest in genetic sequencing technology to ensure accurate and reliable results.
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• • Results are typically ready within a few weeks. We provide a detailed report that explains the presence or absence of these key genetic markers and what they mean for your lactose digestion capabilities.

Step 4: Consultation and Support

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• • Upon receiving your results, you may have questions or need advice on how to proceed. London Blood Tests offers follow-up consultations to discuss your results in detail and provide guidance on dietary modifications and other lifestyle adjustments based on your genetic profile.

This comprehensive approach ensures that not only do you receive precise information about your lactose tolerance, but you also gain the support necessary to make meaningful changes to your diet and lifestyle.

Benefits of Knowing Your Genetic Makeup

Understanding your genetic predisposition to lactose intolerance through the Genetic Lactose Intolerance Test offers several significant advantages:

· Personalized Diet Planning: Armed with knowledge about your body's ability to process lactose, you can tailor your diet to better suit your genetic makeup. This might mean adjusting the amount of dairy you consume or selecting lactose-free alternatives to avoid discomfort and enhance digestive health.

· Improved Digestive Health: By aligning your diet with your genetic predisposition, you can significantly reduce symptoms associated with lactose intolerance, such as bloating, gas, and abdominal pain. This leads to improved overall digestive health and comfort.

· Informed Health Decisions: The insights from your genetic test results equip you with the information needed to make informed decisions about your health and dietary needs. This empowerment can contribute to a more proactive approach to managing your well-being.

· Family Health Planning: For families, understanding the genetic traits you may pass on can help in planning children's diets and health strategies early on. Knowing whether a child might be lactose intolerant allows parents to make dietary adjustments that prevent discomfort and promote optimal development.

· Long-Term Health Benefits: Beyond immediate dietary changes, knowing your lactose tolerance status can help prevent future health issues related to improper digestion of dairy products, such as nutrient deficiencies and chronic digestive problems.

These benefits highlight the importance of genetic testing not just as a diagnostic tool, but as a cornerstone for a proactive and personalised approach to health and nutrition.

Lactose intolerance can significantly impact your quality of life, dictating dietary choices and daily comfort. The Genetic Lactose Intolerance Test offered by London Blood Tests provides a scientific and personalised way to understand your body’s capabilities, helping you make informed decisions about your diet and health. By identifying specific genetic markers associated with lactase persistence, this test enables a tailored approach to nutrition that aligns with your unique genetic profile.