17-Hydroxyprogesterone
Private 17-Hydroxyprogesterone blood test in London for £155, measuring one adrenal steroid hormone with results in around 1 week.
Turnaround time
1 week
Biomarkers count
1
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Overview of the 17-Hydroxyprogesterone
The 17-Hydroxyprogesterone blood test is a specialist endocrine investigation that measures 17-hydroxyprogesterone, commonly abbreviated to 17-OHP.
17-OHP is a naturally occurring steroid hormone produced mainly by the adrenal glands, with smaller amounts produced by the ovaries and testes.
It forms part of the biochemical pathway used by the body to produce cortisol and other steroid hormones.
The test contains 1 biomarker: 17-Hydroxyprogesterone. One of its most important clinical uses is supporting investigation of congenital adrenal hyperplasia (CAH), particularly the common form caused by 21-hydroxylase deficiency.
When this enzyme pathway is impaired, 17-OHP can accumulate and become significantly elevated.
In adults, testing may also be considered when investigating symptoms of androgen excess, including irregular periods, excess facial or body hair, persistent acne or fertility difficulties.
These symptoms are more commonly associated with conditions such as polycystic ovary syndrome (PCOS), so 17-OHP may form part of a wider endocrine assessment to help investigate alternative causes such as non-classic congenital adrenal hyperplasia.
Because 17-OHP varies with time of day, menstrual-cycle phase, age and medication, sample timing can be important when results are interpreted.
What Does the 17-Hydroxyprogesterone?
This test measures 1 biomarker.
17-Hydroxyprogesterone
Measures 17-OHP, a steroid hormone involved in the pathway used to produce cortisol. Elevated concentrations may occur when certain adrenal enzyme pathways are impaired, particularly in congenital adrenal hyperplasia caused by 21-hydroxylase deficiency.
Who May Benefit From the 17-Hydroxyprogesterone?
This test may be suitable for people requiring targeted investigation of the adrenal steroid pathway, particularly where congenital adrenal hyperplasia or unexplained androgen excess is being considered.
Suspected congenital adrenal hyperplasia - 17-OHP is an important biochemical marker for CAH, particularly 21-hydroxylase deficiency.
Possible non-classic congenital adrenal hyperplasia - Milder forms of CAH can present later in life and may produce symptoms similar to PCOS.
Unexplained androgen excess - Testing may be considered when excess facial or body hair, persistent acne or other androgen-related symptoms require further investigation.
Irregular or absent menstrual periods - 17-OHP may form part of a wider hormonal assessment when menstrual disturbance occurs alongside possible androgen excess.
Possible PCOS requiring differential diagnosis - 17-OHP can help clinicians investigate whether symptoms may relate to non-classic CAH rather than, or in addition to, PCOS.
Fertility concerns with suspected adrenal hormone abnormalities - Specialist testing may be requested when an endocrine cause of ovulatory or reproductive problems is being considered.
Family history of congenital adrenal hyperplasia - Testing may be appropriate where there is a clinically relevant family history or known genetic risk.
Previously abnormal 17-OHP result - Repeat testing or further endocrine assessment may help clarify an earlier abnormality.
Known congenital adrenal hyperplasia - 17-OHP may form part of specialist monitoring, although interpretation depends on treatment and sample timing.
How to Prepare
Do not stop corticosteroids, hormonal medication or other prescribed treatment simply to alter a 17-OHP result unless specifically instructed by the clinician responsible for your care.
Sample timing can materially affect interpretation, so follow any individual instructions provided by your endocrinologist, gynaecologist or other healthcare professional.
Symptoms and Reasons to Consider the 17-Hydroxyprogesterone
You may wish to consider the 17-Hydroxyprogesterone test when symptoms suggest androgen excess or when congenital adrenal hyperplasia is being investigated.
Excess facial or body hair - Hirsutism can occur with increased androgen activity and may prompt investigation of PCOS, non-classic CAH and other endocrine causes.
Persistent or severe acne - Significant androgen-related acne may lead to wider hormonal assessment.
Irregular menstrual cycles - Infrequent, unpredictable or absent periods can occur in several endocrine conditions.
Difficulty conceiving - Hormonal disorders affecting ovulation may contribute to fertility difficulties.
Unexpectedly high androgen results - Elevated testosterone, androstenedione or related biomarkers may prompt further investigation of adrenal steroid production.
Early development of androgen-related characteristics - Premature pubic hair or other androgen-related changes in children require specialist paediatric endocrine assessment.
Known congenital adrenal hyperplasia - Repeat 17-OHP measurement may be used within specialist monitoring.
Previous borderline 17-OHP result - Repeat appropriately timed testing may be recommended where an earlier result was inconclusive.
These symptoms are not specific to congenital adrenal hyperplasia. PCOS and several other endocrine or reproductive conditions can cause similar features.
A raised 17-OHP result does not independently establish a diagnosis of CAH. Borderline results may require appropriately timed repeat testing or further endocrine investigations such as stimulation testing.
Rapidly progressive androgen-related symptoms, significant virilisation or other concerning endocrine features should be assessed by an appropriately qualified healthcare professional.
How to Book Your 17-Hydroxyprogesterone in London
Booking your 17-Hydroxyprogesterone test with London Blood Tests is simple and designed to fit around your schedule.
Choose the 17-Hydroxyprogesterone
Select the 17-Hydroxyprogesterone test online and review the included adrenal steroid hormone biomarker before booking.
Select your sample collection option
Choose an in-clinic blood draw (+£35) or a home or hotel phlebotomy visit (+£60) where a qualified phlebotomist collects your sample.
Attend your appointment
A trained professional will collect your blood sample safely and efficiently, taking any relevant timing instructions into account.
Laboratory analysis
Your sample is sent to the laboratory, where 17-Hydroxyprogesterone is measured using specialist endocrine analysis.
Receive your results securely
Your results are sent securely by email, ready to review yourself or discuss with a GP, endocrinologist, gynaecologist, fertility specialist or other suitably qualified healthcare professional.
When Will I Receive My Results?
The expected turnaround time for the 17-Hydroxyprogesterone test is approximately 1 week after your sample arrives at the laboratory.
Results are sent securely by email once specialist laboratory analysis and authorisation are complete. Turnaround therefore begins when the laboratory receives the sample rather than necessarily from the time your blood is collected.
Specialist endocrine testing may occasionally require repeat analysis, confirmation or additional laboratory review, which can extend the expected turnaround.
Understanding Your Results
Your 17-Hydroxyprogesterone result shows the concentration of 17-OHP measured in your blood according to the reference interval and laboratory method used.
A raised concentration may indicate increased production within the adrenal steroid pathway.
Marked elevations are particularly associated with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency.
However, mild or borderline elevations do not automatically establish a diagnosis. The significance of the result depends on age, symptoms, sex, menstrual-cycle phase, time of sampling and medication.
17-OHP can naturally be higher later in the menstrual cycle and also varies throughout the day.
Where a baseline result is borderline but non-classic congenital adrenal hyperplasia remains clinically suspected, an endocrinologist may recommend further testing.
In people presenting with excess hair growth, acne or menstrual irregularity, a normal 17-OHP result may make non-classic CAH less likely but does not establish another diagnosis such as PCOS.
Results should therefore be interpreted according to the laboratory reference range and within the wider endocrine and clinical context.
Why Book With London Blood Tests?
Private 17-OHP testing in London - Access specialist 17-Hydroxyprogesterone testing through London Blood Tests.
Targeted adrenal steroid measurement - Measure 17-OHP without having to book a broad hormone profile.
Relevant to congenital adrenal hyperplasia investigation - 17-OHP is an important biochemical marker when CAH is clinically suspected.
Useful in androgen excess assessment - Testing can provide additional information where hirsutism, acne or irregular periods require investigation.
Relevant when distinguishing non-classic CAH from PCOS - 17-OHP can contribute to the wider differential diagnosis of androgen excess.
Specialist laboratory analysis - Your sample is processed using dedicated endocrine testing methods.
Clinic and home visit options - Choose an in-clinic blood draw or arrange home or hotel phlebotomy depending on location and availability.
Secure results by email - Receive your authorised laboratory result securely once analysis is complete.
Clear pricing before booking - The 17-Hydroxyprogesterone test is priced at £155, with sample collection charges shown separately.
Private 17-Hydroxyprogesterone Blood Test in London
London Blood Tests provides the 17-Hydroxyprogesterone blood test in London for people requiring specialist investigation of adrenal steroid hormone production.
The test costs £155 and measures one biomarker: 17-Hydroxyprogesterone. It is particularly relevant when congenital adrenal hyperplasia is being investigated and can also contribute to assessment of unexplained androgen excess.
Clinic appointments are available alongside home and hotel phlebotomy depending on location and availability, providing flexible options for people looking for a private 17-Hydroxyprogesterone blood test in London or specialist adrenal hormone testing near them.
A 17-OHP result should not be interpreted independently. A GP, endocrinologist or gynaecologist may recommend additional investigations depending on symptoms, sample timing and other hormone results.