What is the Adenovirus by PCR Test?

The Adenovirus by PCR test detects the genetic material (DNA) of adenovirus using polymerase chain reaction (PCR) technology. PCR is highly sensitive and can identify active viral infection even when viral levels are low or symptoms are early.

Adenoviruses are common viruses that can infect the respiratory tract, gastrointestinal system, eyes and urinary tract. While infections are often mild and self-limiting, they can cause significant illness in children, immunocompromised individuals or those with underlying health conditions.

This test confirms current infection rather than past exposure, making it a valuable diagnostic tool when rapid and accurate identification is required.

Why do I need a test for Adenovirus?

You may need this test if you have symptoms consistent with viral infection and other common causes have been ruled out. Adenovirus can mimic bacterial infections or other respiratory viruses, making laboratory confirmation important to avoid unnecessary antibiotics and guide appropriate care.

PCR testing is particularly important in vulnerable populations, outbreaks, or persistent infections, where early detection helps reduce transmission and supports clinical decision-making.

Symptoms and scenarios where testing is recommended:

• Fever with respiratory symptoms
• Persistent cough or sore throat
• Conjunctivitis (red or painful eyes)
• Diarrhoea or vomiting, especially in children
• Prolonged viral symptoms without clear cause
• Suspected viral outbreak in schools or care settings
• Infection in immunocompromised individuals
• Pre-admission or infection control screening

Benefits of the Adenovirus PCR Test

• Confirms active adenovirus infection
  Detects viral DNA, confirming current infection rather than past exposure.
• Highly sensitive and specific
  PCR technology provides accurate results even with low viral load.
• Reduces unnecessary antibiotic use
  Differentiates viral illness from bacterial infection.
• Supports infection control decisions
  Helps limit spread in schools, hospitals or care facilities.
• Useful in immunocompromised patients
  Enables early diagnosis in those at higher risk of complications.
• Detects infection early
  Identifies virus before symptoms fully develop.
• Supports targeted clinical management
  Guides appropriate monitoring and supportive care.
• Suitable for outbreak investigations
  Useful for identifying the cause of clustered infections.

Step-by-Step: How Testing Works

Choose your preferred testing method

Testing can be carried out at a UK clinic or via professionally supported sample collection, depending on sample type.

Option 1 – In-Clinic Sample Collection

1. Attend your chosen UK clinic.
2. A healthcare professional collects the appropriate sample (e.g. swab, stool or urine, depending on symptoms).
3. The sample is sent to the laboratory for PCR analysis.
4. Results are delivered securely online.

Option 2 – Supported Collection (UK-wide)

1. Arrange a supported sample collection if appropriate.
2. The sample is collected following strict infection-control protocols.
3. It is transported safely to the laboratory.
4. Results are uploaded digitally.

Access your report

Results can be downloaded and shared with your GP or specialist if needed.

Your Results Explained

Negative Result

A negative PCR result means adenovirus DNA was not detected.
This suggests adenovirus is unlikely to be the cause of your symptoms at the time of testing.

Normal / Expected Finding

An expected result confirms absence of detectable adenovirus infection.
Symptoms may be caused by another viral or non-infectious condition.

Positive Result

A positive result confirms an active adenovirus infection.
This indicates current viral replication and explains compatible clinical symptoms.
Management usually focuses on supportive care unless complications arise.