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Anti-Liver Cytosol Antibodies

Autoimmune Tests
104.00

Highly specific test for autoimmune liver conditions with clear results and flexible testing options.

Turnaround time

Results available 5 days after arrival in lab. Doctor's report sent the day after results available (if required)

Biomarkers count

1

Same-Day Appointments
UKAS Accredited Labs

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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Anti-Liver Cytosol Antibodies

What Is This Blood Test?

 

The Anti-Liver Cytosol Antibodies test detects autoantibodies that target components inside liver cells. These antibodies are strongly associated with autoimmune liver conditions, especially autoimmune hepatitis type 2. Identifying them early helps guide diagnosis, treatment decisions, and monitoring.

 

Benefits of the Test

 

  • Helps detect autoimmune hepatitis type 2 at an early stage.
  • Useful for evaluating unexplained liver inflammation or abnormal liver enzymes.
  • Supports differential diagnosis when other autoimmune markers are inconclusive.
  • Provides clinicians with valuable information for monitoring disease progression or treatment response.
  • Helps rule out other causes of liver dysfunction.

 

Why Do I Need an Anti-Liver Cytosol Antibodies Test?

 

You may need this test if you experience:

  • Persistent fatigue
  • Jaundice
  • Abdominal discomfort
  • Unexplained nausea
  • Itchy skin
  • Dark urine or pale stools
  • Joint pain
  • Enlarged liver (found during examination)

 

This test is particularly relevant for:

  • Individuals with abnormal liver blood tests (ALT, AST, GGT)
  • Those suspected of autoimmune hepatitis
  • People with family history of autoimmune diseases
  • Patients with chronic liver inflammation of unknown cause

 

How It Works (Step by Step)

 

In-Clinic Service

Available across various UK locations.

  1. Book your appointment.
  2. Attend the clinic for a venous blood draw (£35).
  3. Your sample is processed in a UK-accredited laboratory.
  4. Results are delivered securely online.

 

At-Home Service

For home or hotel blood draws:

  1. Book an at-home phlebotomy visit (£60).
  2. A qualified phlebotomist collects your sample.
  3. Sample is couriered to the lab the same day.
  4. Receive your digital results in the stated turnaround time.

 

 

Results – How to Interpret Them (Using Numerical Values)

 

  • Negative (<1:40 or below assay cut-off)
    No detectable Anti-Liver Cytosol antibodies. Autoimmune hepatitis type 2 is unlikely.
  • Low-Positive (around 1:40–1:80 or slightly above cut-off)
    Mild antibody presence. May warrant repeat testing or correlation with liver enzymes.
  • Positive (>1:80 or significantly above cut-off)
    Strong likelihood of autoimmune hepatitis type 2. Further clinical assessment is recommended.
  • Very High Positive (markedly elevated above reference range)
    Suggests active autoimmune liver disease. Follow-up with a liver specialist is typically required.

 

(Exact numerical ranges may differ slightly between laboratories; clinicians interpret results alongside symptoms and liver enzyme levels.)

How It Works

Simple steps to get your results

1

Book Online

Choose your test online and book in seconds. Select your preferred clinic location or home visit option.

2

Visit or Test at Home

Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.

3

Get Your Results

Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.

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How to Prepare for Your Test

Follow these guidelines for accurate results

Sample Timing

Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.

Fasting & Hydration

Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.

Medications & Supplements

Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.

Hormones & Menstrual Cycle

For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.

If you have any questions or special circumstances, our team is happy to advise before your appointment.

Frequently Asked Questions

It helps identify autoimmune liver conditions, especially autoimmune hepatitis type 2.

No. ANA is a broad autoimmune marker; Anti-Liver Cytosol is highly specific for liver autoimmunity.

No fasting is required.

Some immunosuppressive drugs may lower antibody levels. Always inform the clinician.

Turnaround time is based on the laboratory schedule and will be shown on your results page.

It strongly suggests it but isn’t diagnostic on its own. Doctors assess liver enzymes, symptoms, and imaging.

Yes. Other forms of autoimmune or non-autoimmune liver disease may still be present.

Yes, antibody levels can help track disease activity over time.

Anyone with unexplained liver inflammation, abnormal ALT/AST, or suspected autoimmune hepatitis.

Yes, optional GP consultations are available if you need help interpreting your results.

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