Bicarbonate
This test measures bicarbonate levels in the blood. It helps assess acid–base balance and detect metabolic or respiratory disturbances.
Turnaround time
1 day
Biomarkers count
1
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Details about Bicarbonate
What is the Bicarbonate Test?
The Bicarbonate test measures the concentration of bicarbonate (HCO₃⁻) in the blood, a key buffer that helps maintain the body’s acid–base balance. Bicarbonate works with the lungs and kidneys to keep blood pH within a narrow, healthy range.
Bicarbonate levels are closely linked to kidney function, lung function and overall metabolic status. Abnormal levels can indicate disorders affecting acid production, acid elimination or bicarbonate regulation.
This test is commonly included as part of electrolyte panels and metabolic profiles.
Why do I need a test for Bicarbonate?
You may need this test if there is concern about acid–base imbalance, kidney disease or respiratory conditions. It is frequently used to investigate unexplained fatigue, breathing difficulties or electrolyte abnormalities.
Bicarbonate testing helps identify metabolic acidosis or alkalosis and supports diagnosis and monitoring of kidney, lung and systemic conditions.
Symptoms and scenarios where testing is recommended:
- Chronic kidney disease
- Shortness of breath or respiratory disorders
- Persistent fatigue or weakness
- Vomiting or diarrhoea
- Electrolyte imbalance
- Suspected metabolic acidosis or alkalosis
- Monitoring intensive or chronic illness
- Use of certain medications affecting acid balance
Benefits of the Bicarbonate Test
- Assesses acid–base balance
Key marker of metabolic pH regulation. - Supports kidney function evaluation
Kidneys play a major role in bicarbonate control. - Aids diagnosis of metabolic disorders
Identifies acidosis or alkalosis. - Useful in respiratory disease assessment
Reflects compensation for lung-related pH changes. - Monitors chronic disease progression
Important in kidney and lung disease management. - Guides treatment decisions
Helps adjust fluids, medications or ventilation. - Simple and widely used blood test
Part of routine metabolic panels. - Supports electrolyte interpretation
Complements sodium, potassium and chloride results.
Step-by-Step: How Testing Works
Choose your preferred testing method
You can attend one of our UK partner clinics or arrange a home or hotel visit with a mobile phlebotomist.
Option 1 – In-Clinic Blood Draw
- Select your nearest UK clinic and book an appointment.
- A clinician or phlebotomist collects a venous blood sample.
- The sample is analysed for bicarbonate concentration.
- Results are delivered securely online.
Option 2 – Home or Hotel Phlebotomy (+£60)
- Book a UK-wide home or hotel visit at a convenient time.
- A trained phlebotomist collects your blood sample on-site.
- The sample is transported to the laboratory.
- Results are uploaded digitally without the need to travel.
Your Results Explained
Low Levels
Low bicarbonate levels suggest metabolic acidosis or reduced acid buffering.
This may be seen in kidney disease, uncontrolled diabetes or severe diarrhoea.
Typical UK reference range: ~22–29 mmol/L.
Normal Levels
Normal bicarbonate levels indicate balanced acid–base regulation.
This suggests normal kidney and respiratory compensation.
High Levels
High bicarbonate levels suggest metabolic alkalosis or compensation for chronic respiratory disease.
Causes may include prolonged vomiting, diuretic use or chronic lung conditions.
How It Works
Simple steps to get your results
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.