Bilirubin (Urine)
Private Bilirubin (Urine) test in London for £43, measuring one urinary bilirubin marker with results in approximately 1 business day.
Turnaround time
1 business day
Biomarkers count
1
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Overview of the Bilirubin (Urine)
The Bilirubin (Urine) test checks a urine sample for the presence of bilirubin.
Bilirubin is produced during the normal breakdown of haemoglobin and is subsequently processed by the liver.
Unconjugated bilirubin is not water-soluble and is not normally excreted into urine.
After bilirubin has been conjugated by the liver, however, it becomes water-soluble. If conjugated bilirubin builds up in the bloodstream, some can pass through the kidneys and appear in urine.
The test contains 1 biomarker: Bilirubin (Urine).
Urinary bilirubin can therefore provide supporting information when liver or bile duct disease is being investigated.
A positive result may occur with cholestasis, biliary obstruction or hepatocellular conditions that cause conjugated bilirubin to increase.
Urine bilirubin may sometimes become detectable before visible jaundice develops.
A negative result does not exclude liver disease because many liver and haematological conditions do not cause conjugated bilirubin to enter the urine.
The result should therefore be interpreted alongside blood bilirubin fractions, liver enzymes, symptoms and other investigations where appropriate.
What Does the Bilirubin (Urine) Test Check?
This test measures 1 biomarker.
Bilirubin (Urine)
Detects conjugated bilirubin excreted into urine. Bilirubinuria can occur when water-soluble conjugated bilirubin accumulates in the blood because of selected liver or biliary conditions.
Who May Benefit From the Bilirubin (Urine) Test?
This urine test may be useful where symptoms or previous laboratory findings suggest abnormal bilirubin excretion, liver dysfunction or impaired bile flow.
People with dark urine - Conjugated bilirubin can contribute to unusually dark urine when blood concentrations are increased.
People with unexplained jaundice - Urinary bilirubin may provide additional information alongside blood bilirubin testing.
People with pale stools and dark urine - This combination can occur when normal bile flow is impaired.
People with abnormal liver-function tests - Urine bilirubin may provide supplementary information where blood liver markers are already abnormal.
Possible cholestasis - Conjugated bilirubin can enter urine when bile excretion from the liver is impaired.
Possible bile duct obstruction - Bilirubinuria can occur where normal bile drainage is obstructed.
Known liver disease requiring further assessment - Urine testing may occasionally form part of a broader liver evaluation.
Previously positive urine bilirubin - Repeat testing may help determine whether bilirubin remains detectable.
Specialist-requested urine testing - The test can be arranged privately where a GP, hepatologist or gastroenterologist has requested urinary bilirubin measurement.
How to Prepare
Do not substantially alter fluid intake simply to influence the urine result.
A fresh, correctly handled specimen is important because bilirubin can break down in urine over time and with light exposure.
Symptoms and Reasons to Consider the Bilirubin (Urine) Test
You may wish to consider the Bilirubin (Urine) test where symptoms suggest conjugated bilirubin may be entering the urine.
Dark brown or tea-coloured urine - Conjugated bilirubin can darken urine when present at increased concentrations.
Yellowing of the skin or eyes - Jaundice can occur when bilirubin accumulates in the body.
Pale or clay-coloured stools - Reduced bile pigment reaching the bowel may cause stools to become lighter.
Generalised itching - Cholestasis can cause significant itching in some people.
Upper abdominal discomfort - Liver and biliary disorders can occasionally cause pain or discomfort.
Unexplained nausea or reduced appetite - These symptoms can accompany liver or biliary illness but are non-specific.
Previous abnormal liver blood tests - Urinary bilirubin may provide supporting information within a wider liver assessment.
Known bile duct or gallbladder problems - Testing may occasionally be useful alongside blood tests and imaging.
These symptoms have many potential causes. Urinary bilirubin does not diagnose a particular liver or gallbladder condition.
New jaundice, fever with abdominal pain, severe right upper abdominal pain, persistent vomiting, confusion or rapidly worsening illness requires prompt medical assessment.
How to Book Your Bilirubin (Urine) Test
Booking your Bilirubin (Urine) test with London Blood Tests is straightforward.
Choose the Bilirubin (Urine)
Select the Bilirubin (Urine) test online and review the urine sample requirements before booking.
Select your sample collection option
Arrange the appropriate urine collection container and confirm where the completed sample should be returned.
Attend your appointment
Where kit collection or supervised sample provision is required, attend the arranged location and follow the supplied collection instructions.
Laboratory analysis
Your urine sample is sent to the laboratory for detection of bilirubin.
Receive your results securely
Your authorised result is sent securely by email, ready to review yourself or discuss with a GP, hepatologist or gastroenterologist.
When Will I Receive My Results?
The expected turnaround time for the Atypical Pneumonia Screen is approximately 7 business days.
Results are sent securely by email once specialist laboratory analysis and authorisation are complete. Turnaround generally begins when the laboratory receives your blood sample rather than necessarily from the time it is collected.
Specialist serology can occasionally require repeat analysis, confirmatory review or additional laboratory processing, which may extend the expected turnaround.
Understanding Your Results
A negative result means bilirubin was not detected in the urine according to the laboratory method used.
This is expected in healthy urine.
However, a negative urine bilirubin result does not exclude all liver disease or bilirubin abnormalities.
Unconjugated bilirubin, for example, is not water-soluble and therefore does not normally pass into urine.
A positive result indicates that conjugated bilirubin is present in the urine.
This can occur when conjugated bilirubin accumulates in the bloodstream because of impaired bile excretion, cholestasis, biliary obstruction or selected hepatocellular conditions.
The result should not be interpreted by itself.
Blood total, direct and indirect bilirubin, ALP, GGT, ALT, AST and imaging may provide additional information depending on the clinical circumstances.
Why Book With London Blood Tests?
Private urine bilirubin testing in London - Access targeted Bilirubin (Urine) testing through London Blood Tests.
Non-invasive sample collection - The test uses urine rather than requiring a venous blood sample.
Relevant to dark urine and jaundice assessment - Bilirubinuria can provide additional information when liver or biliary disease is being investigated.
Useful alongside blood bilirubin testing - Urine bilirubin can complement direct, indirect and total blood bilirubin measurements.
Relevant to bile-flow investigation - Conjugated bilirubin may appear in urine when normal bile excretion is impaired.
Fast laboratory turnaround - Results are expected approximately 1 business day after the sample reaches the laboratory.
Secure results by email - Receive your authorised laboratory result securely.
Clear pricing before booking - The Bilirubin (Urine) test is priced at £43, with any applicable collection charges shown separately.
Private Bilirubin (Urine) Test in London
London Blood Tests provides the Bilirubin (Urine) test in London for people requiring targeted assessment of urinary bilirubin.
The test costs £43 and measures one biomarker: Bilirubin (Urine).
Testing may provide useful supplementary information where jaundice, dark urine, cholestasis or a bile duct problem is being investigated.
The sample is collected in an appropriate urine container and returned for laboratory analysis.
Results should be interpreted alongside symptoms and blood liver investigations rather than used as a standalone diagnosis.