Chagas Disease Serology (S.American Trypanosomiasis) T. Cruzi
This test detects antibodies to Trypanosoma cruzi, the parasite that causes Chagas disease. It helps identify past or chronic infection.
Turnaround time
11 days
Biomarkers count
1
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Details about Chagas Disease Serology (S.American Trypanosomiasis) T. Cruzi
What is the Chagas Disease Serology (Trypanosoma cruzi) Test?
The Chagas Disease Serology test detects antibodies produced by the immune system in response to infection with Trypanosoma cruzi. This parasite causes Chagas disease, also known as South American trypanosomiasis, and is primarily transmitted by triatomine insects (“kissing bugs”).
After the initial acute phase, the infection often becomes chronic and may remain asymptomatic for many years. During this chronic phase, serological antibody testing is the primary method for diagnosis.
This test is commonly used for screening individuals with past exposure risk, migrants from endemic regions and those with unexplained cardiac or gastrointestinal symptoms.
Why do I need a test for Chagas Disease Serology?
You may need this test if you have lived in or travelled to areas where Chagas disease is endemic, particularly parts of Central and South America. Many infected individuals are unaware they carry the parasite until complications develop years later.
Early identification allows appropriate monitoring and treatment, helping reduce the risk of long-term heart and digestive complications.
Symptoms and scenarios where testing is recommended:
- Birth or long-term residence in Central or South America
- History of insect exposure in endemic areas
- Unexplained cardiomyopathy or arrhythmias
- Chronic digestive symptoms (megacolon or megaoesophagus)
- Screening during pregnancy
- Blood or organ donor screening
- Unexplained heart failure at a young age
- Family history of Chagas disease
Benefits of the Chagas Disease Serology Test
- Identifies chronic Trypanosoma cruzi infection
Detects immune response to long-standing infection. - Supports early intervention and monitoring
Enables proactive management of complications. - Essential for cardiac risk assessment
Chagas disease commonly affects the heart. - Useful in asymptomatic individuals
Identifies infection before symptoms develop. - Supports pregnancy and donor screening
Reduces transmission risk. - Widely accepted diagnostic approach
Standard method for chronic Chagas disease. - Non-invasive blood-based testing
Simple venous blood sample. - Guides specialist referral and care
Supports infectious disease and cardiology input.
Step-by-Step: How Testing Works
Choose your preferred testing method
You can attend one of our UK partner clinics or arrange a home or hotel visit with a mobile phlebotomist.
Option 1 – In-Clinic Blood Draw
- Select your nearest UK clinic and book an appointment.
- A clinician or phlebotomist collects a venous blood sample.
- The sample is analysed for Trypanosoma cruzi antibodies.
- Results are delivered securely online.
Option 2 – Home or Hotel Phlebotomy (+£60)
- Book a UK-wide home or hotel visit at a convenient time.
- A trained phlebotomist collects your blood sample on-site.
- The sample is transported to the laboratory.
- Results are uploaded digitally without the need to travel.
Your Results Explained
Negative Result
No antibodies to Trypanosoma cruzi detected.
This suggests no evidence of current or past Chagas disease.
Positive Result
Antibodies to Trypanosoma cruzi detected.
This indicates past or chronic infection and requires further clinical evaluation.
Indeterminate Result
Results are inconclusive.
Repeat testing or confirmatory assays may be recommended.
Serological results should be interpreted alongside clinical history and exposure risk.
How It Works
Simple steps to get your results
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.