What is the Clam IgE level test?

The Clam IgE level test is a blood test that measures Immunoglobulin E (IgE) antibodies directed against proteins found in clams, a type of shellfish. IgE antibodies are responsible for immediate allergic reactions, which can occur shortly after exposure.

Shellfish allergy is one of the most common and potentially severe food allergies. This test specifically identifies IgE-mediated clam allergy, distinguishing it from non-allergic food intolerance or delayed sensitivity.

The test is widely used in allergy clinics to assess suspected shellfish reactions in both adults and children.

Why do I need a Clam IgE test?

Clam allergy can cause rapid and sometimes severe allergic reactions. Identifying IgE sensitisation helps prevent accidental exposure and reduces the risk of serious outcomes.

You may need a Clam IgE test if you experience symptoms shortly after eating clams or other shellfish.

You may benefit from this test if you have:

• Hives or skin rash after eating clams
• Swelling of lips, face, tongue, or throat
• Itching or tingling in the mouth
• Wheezing, coughing, or shortness of breath
• Nausea, vomiting, or abdominal pain
• Dizziness or fainting
• A history of shellfish reactions
• Unclear or conflicting allergy test results

Shellfish allergy often persists into adulthood and may worsen with repeated exposure.

Benefits of the Clam IgE test

• Confirms true clam allergy
  Detects IgE-mediated immune response.
• Assesses immediate reaction risk
  Helps evaluate severity potential.
• Supports safe dietary avoidance
  Guides elimination of clams and related shellfish.
• Clinically recognised allergy marker
  Used in standard allergy diagnostics.
• Suitable for children and adults
  Used in paediatric and adult allergy assessment.
• Simple blood test
  No food challenge required.
• Useful when skin testing is unsuitable
  Safer option for high-risk individuals.
• Distinguishes allergy from intolerance
  Prevents unnecessary dietary restriction.

Step by step – how the test works

You can access Clam IgE testing UK-wide through two options:

1. Clinic appointment
   Choose your nearest UK clinic, where a healthcare professional will take your blood sample.
2. At-home or hotel visit (£60 extra)
   A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.

Your sample is analysed in an accredited UK laboratory, and results are delivered securely.

Your results explained

Negative / low Clam IgE

Suggests no evidence of IgE-mediated clam allergy. Symptoms may be due to intolerance or another cause.

Typical UK reference range:

• < 0.35 kUA/L

Moderate Clam IgE levels

Indicate sensitisation to clam proteins. Clinical relevance depends on symptoms and exposure history.

Typical UK interpretation:

• 0.35–3.5 kUA/L

High Clam IgE levels

Suggest a strong allergic response and increased risk of immediate reactions.

Typical UK interpretation:

• > 3.5 kUA/L

Results must always be interpreted alongside clinical symptoms.