What is the COVID-19 (SARS-CoV-2) RNA by PCR test?

The COVID-19 (SARS-CoV-2) RNA by PCR test detects genetic material (RNA) from the SARS-CoV-2 virus. PCR (Polymerase Chain Reaction) is a highly sensitive laboratory method that amplifies viral RNA, allowing detection even at very low levels.

This test confirms active infection, not past exposure or immunity. It is widely used in clinical diagnosis, workplace screening, travel-related testing (where applicable), and infection control.

The next-day turnaround option provides fast and reliable results while maintaining laboratory accuracy.

Why do I need a COVID-19 PCR test?

PCR testing is essential when confirming whether someone is currently infected with COVID-19, especially in situations where accuracy is critical.

You may need a COVID-19 PCR test if you:

• Have COVID-19 symptoms
• Have been in close contact with a confirmed case
• Require confirmation of active infection
• Need testing for work or clinical clearance
• Are immunocompromised or high-risk
• Have symptoms despite a negative rapid test
• Require a definitive diagnostic result

Common symptoms that may prompt testing include:

• Fever or chills
• Cough
• Sore throat
• Loss of taste or smell
• Fatigue
• Muscle aches
• Headache
• Shortness of breath

Benefits of the COVID-19 PCR test

• Gold-standard diagnostic accuracy
  Highest sensitivity for active infection.
• Detects early infection
  Identifies virus before symptoms peak.
• Next-day results
  Fast turnaround without compromising accuracy.
• Clinically recognised worldwide
  Standard diagnostic method for COVID-19.
• More reliable than rapid tests
  Lower false-negative rates.
• Suitable for symptomatic and asymptomatic testing
  Used in screening and diagnosis.
• Supports infection control decisions
  Helps protect others.
• Accredited laboratory analysis
  Ensures test reliability.

Step by step – how the test works

You can access COVID-19 PCR testing UK-wide through two options:

1. Clinic appointment
   Attend your nearest UK clinic for a swab sample collection by a healthcare professional.
2. At-home or hotel visit (£60 extra)
   A qualified healthcare professional attends your home or hotel to collect the sample.

The sample is analysed in an accredited laboratory, with next-day results delivered securely.

Your results explained

Negative (SARS-CoV-2 RNA not detected)

No viral RNA detected at the time of testing. This suggests no active infection, though very early exposure cannot be completely excluded.

Typical laboratory interpretation:

• SARS-CoV-2 RNA: Not detected

Positive (SARS-CoV-2 RNA detected)

Confirms active COVID-19 infection. Isolation and public health guidance should be followed.

Typical laboratory interpretation:

• SARS-CoV-2 RNA: Detected

Inconclusive / invalid result

The sample may be insufficient or affected by technical factors. Repeat testing may be required.

Results should always be interpreted alongside symptoms and exposure history.