What is the Cow’s Milk IgE level test?

The Cow’s Milk IgE level test is a blood test that measures Immunoglobulin E (IgE) antibodies specifically directed against proteins found in cow’s milk. IgE antibodies are responsible for immediate allergic reactions, which can occur within minutes to a few hours after exposure.

This test focuses on true immune-mediated milk allergy rather than intolerance or delayed sensitivity. It is commonly used in allergy clinics to support diagnosis, risk assessment, and management of milk allergy in both children and adults.

Cow’s milk is one of the most common food allergens, particularly in infancy and early childhood, though it can also persist into adulthood.

Why do I need a Cow’s Milk IgE test?

A cow’s milk allergy can cause rapid and sometimes severe reactions. Identifying IgE-mediated allergy is essential for avoiding exposure and preventing potentially dangerous outcomes.

This test is particularly important when symptoms occur shortly after consuming milk or dairy-containing foods.

You may need a Cow’s Milk IgE test if you experience:

• Hives or skin rash after milk intake
• Swelling of lips, tongue, face, or throat
• Itching or tingling in the mouth
• Wheezing, coughing, or breathing difficulty
• Vomiting or abdominal pain shortly after dairy
• Dizziness or fainting
• Suspected childhood milk allergy
• Previous allergic reactions to dairy

Unlike intolerance, IgE-mediated milk allergy requires strict avoidance.

Benefits of the Cow’s Milk IgE test

• Confirms true cow’s milk allergy
  Detects IgE-mediated immune response.
• Assesses risk of immediate reactions
  Helps evaluate potential severity.
• Supports safe dietary management
  Guides strict avoidance strategies.
• Essential for anaphylaxis risk assessment
  Helps inform emergency planning.
• Clinically recognised allergy marker
  Used in standard allergy diagnostics.
• Suitable for children and adults
  Commonly used in paediatric testing.
• Simple blood test
  No food challenge required.
• Distinguishes allergy from intolerance
  Avoids unnecessary dietary restriction.

Step by step – how the test works

You can access Cow’s Milk IgE testing UK-wide through two options:

1. Clinic appointment
   Choose your nearest UK clinic, where a healthcare professional will take your blood sample.
2. At-home or hotel visit (£60 extra)
   A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.

Your sample is analysed in an accredited UK laboratory, and results are delivered securely.

Your results explained

Negative / low Cow’s Milk IgE

Suggests no evidence of IgE-mediated cow’s milk allergy. Symptoms may be due to intolerance or non-allergic sensitivity.

Typical UK reference range:

• < 0.35 kUA/L

Moderate Cow’s Milk IgE levels

Indicate sensitisation to cow’s milk proteins. Clinical relevance depends on symptoms and exposure history.

Typical UK interpretation:

• 0.35–3.5 kUA/L

High Cow’s Milk IgE levels

Suggest a strong allergic response and increased risk of immediate reactions to cow’s milk.

Typical UK interpretation:

• > 3.5 kUA/L

Results should always be interpreted alongside clinical symptoms.