Creatinine Clearance
Private Creatinine Clearance test in London for £127.99, assessing kidney filtration using blood and timed urine measurements.
Turnaround time
1 business day
Biomarkers count
1
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Overview of the Creatinine Clearance
The Creatinine Clearance test estimates how effectively the kidneys clear creatinine from the bloodstream.
Unlike serum Creatinine alone, the test combines a blood Creatinine measurement with urinary Creatinine collected during a timed urine collection.
The test reports 1 calculated biomarker: Creatinine Clearance.
A 24-hour urine specimen is typically required.
The laboratory needs the total urine volume, collection duration and serum Creatinine result to calculate clearance correctly.
Incomplete collection is one of the most important sources of error.
Creatinine Clearance provides an estimate of glomerular filtration but is not identical to directly measured GFR.
Because a small amount of creatinine is secreted by kidney tubules in addition to being filtered, Creatinine Clearance can modestly overestimate true filtration.
eGFR is more convenient for routine kidney monitoring, but timed Creatinine Clearance can provide useful additional information in selected clinical circumstances.
What Does the Creatinine Clearance Test Check?
This test measures 1 calculated biomarker.
Creatinine Clearance
Estimates the volume of plasma cleared of creatinine over time by combining serum Creatinine with Creatinine excretion from a timed urine collection.
Who May Benefit From the Creatinine Clearance Test?
Creatinine Clearance may be useful where a timed urine-based estimate of renal filtration has specifically been requested.
People requiring more detailed kidney-filtration assessment - Timed clearance can provide information beyond serum Creatinine alone.
People with unusual body composition - Standard creatinine-based eGFR can occasionally be less representative in people with markedly high or low muscle mass.
People with an unexpected eGFR result - Additional renal measurements may help clarify discordant findings.
People undergoing selected medication assessments - Creatinine Clearance may be relevant when drug dosing depends on renal function.
People with known kidney disease under specialist assessment - Timed clearance can occasionally form part of more detailed renal evaluation.
People specifically instructed to complete a 24-hour urine collection - Accurate timed collection is essential for the calculation.
People with conflicting serum and urine renal findings - Additional clearance assessment can provide complementary information.
People referred by a kidney specialist or GP - The test can be arranged when specifically requested.
How to Prepare
Do not deliberately overhydrate before testing in an attempt to lower Creatinine.
Kidney function is generally best assessed using Creatinine trends together with eGFR and complementary urine markers.
Symptoms and Reasons to Consider the Creatinine Clearance Test
Creatinine Clearance is usually requested because of abnormal kidney results or a need for more precise filtration information rather than because of one specific symptom.
A persistently raised serum Creatinine - Timed clearance may provide complementary information where renal function needs further assessment.
A reduced eGFR that does not fit the clinical picture - Additional testing may occasionally help clarify the result.
Swelling of the legs or ankles with abnormal kidney tests - Fluid retention can occur in renal disease.
Reduced urine output - A significant change in urine production may require kidney assessment.
High blood pressure with evidence of kidney dysfunction - Hypertension and renal disease are closely interconnected.
Known chronic kidney disease requiring more detailed assessment - Specialist renal evaluation may occasionally include timed clearance.
Need for renal-function information before selected medication dosing - Certain treatment decisions rely on an estimate of clearance.
Markedly unusual muscle mass affecting serum Creatinine interpretation - Timed urine information may provide additional context.
These symptoms and circumstances do not establish kidney disease by themselves.
Marked reduction in urine production, rapidly worsening swelling, severe breathlessness, confusion or significant acute illness with suspected kidney dysfunction requires prompt medical assessment.
How to Book Your Creatinine Clearance Test
Creatinine Clearance requires both blood and timed urine measurements.
Choose the Creatinine Clearance
Select the test and review the 24-hour urine requirements.
Select your sample collection option
Obtain the appropriate urine container and arrange the accompanying blood sample.
Attend your appointment
Complete the full timed urine collection and provide the serum blood specimen as instructed.
Laboratory analysis
Serum and urine Creatinine, urine volume and collection duration are used to calculate Creatinine Clearance.
Receive your results securely
Your authorised renal result is delivered securely.
When Will I Receive My Results?
Results are expected approximately 1 business day after all required specimens and collection information reach the laboratory.
An incomplete collection can delay reporting or require recollection.
Understanding Your Results
Creatinine Clearance estimates how effectively the kidneys clear creatinine from circulating plasma.
A lower result can indicate reduced renal filtration.
An unexpectedly low result can also occur if the urine collection was incomplete.
Creatinine Clearance can modestly overestimate true GFR because creatinine undergoes some renal tubular secretion.
Results should be interpreted alongside serum Creatinine, eGFR, urine albumin and other kidney findings where appropriate.
Why Book With London Blood Tests?
Private Creatinine Clearance testing in London - Access a timed urine-based renal filtration assessment.
Blood and urine measurements combined - The calculation incorporates serum and urinary Creatinine.
Useful when additional renal information is required - It can complement routine Creatinine and eGFR.
Clear collection instructions - Accurate timed collection is prioritised.
Fast results - Results are expected approximately 1 business day after all required samples reach the laboratory.
Professional blood collection - The accompanying serum sample can be collected professionally.
Secure reporting - Receive your authorised renal report securely.
Clear pricing - The Creatinine Clearance test costs £127.99.
Private Creatinine Clearance Test in London
London Blood Tests provides private Creatinine Clearance testing in London for people requiring timed assessment of renal filtration.
The test costs £127.99 and reports one calculated biomarker: Creatinine Clearance.
Testing combines serum Creatinine with a complete timed urine collection.
Results are expected approximately 1 business day after all required material reaches the laboratory.