Elastase (Faecal)
This test measures elastase levels in a stool sample. It helps assess pancreatic enzyme production and digestive function.
Turnaround time
1 week
Biomarkers count
1
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Details about Elastase (Faecal)
What is the Elastase (Faecal) Test?
The Elastase (Faecal) test measures pancreatic elastase, an enzyme produced by the pancreas and released into the intestine during digestion. Elastase remains stable as it passes through the gut, making its concentration in stool a reliable marker of pancreatic exocrine function.
This test is widely used to evaluate whether the pancreas is producing sufficient digestive enzymes. It is particularly useful in identifying pancreatic exocrine insufficiency, a condition where digestion and nutrient absorption are impaired.
Why do I need a test for Elastase (Faecal)?
You may need this test if you have persistent digestive symptoms that suggest poor digestion or malabsorption. Pancreatic exocrine insufficiency can develop gradually and is often underdiagnosed.
Identifying reduced enzyme production allows appropriate treatment, such as pancreatic enzyme replacement, helping to improve digestion, nutritional status and quality of life.
Symptoms and scenarios where testing is recommended:
- Chronic diarrhoea
- Fatty or pale stools (steatorrhoea)
- Unexplained weight loss
- Abdominal bloating or discomfort
- Nutrient deficiencies
- Suspected pancreatic disease
- Diabetes with digestive symptoms
- Monitoring known pancreatic conditions
Benefits of the Elastase (Faecal) Test
- Assesses pancreatic enzyme production
Direct indicator of exocrine pancreatic function. - Detects pancreatic exocrine insufficiency
Identifies reduced digestive capacity. - Non-invasive stool-based testing
No blood draw required. - Supports investigation of malabsorption
Helps explain chronic digestive symptoms. - Guides enzyme replacement therapy
Supports appropriate treatment decisions. - Stable and reliable marker
Elastase is not affected by gut transit time. - Useful in chronic pancreatic disease
Including pancreatitis and pancreatic insufficiency. - Improves diagnostic clarity
Differentiates pancreatic from intestinal causes.
Step-by-Step: How Testing Works
Sample Collection Method
This test requires a stool (faecal) sample collected at home or in a clinical setting.
Faecal Sample Collection
- You receive clear instructions and a collection container.
- A small stool sample is collected hygienically.
- The sample is sent to the laboratory for analysis.
- Elastase levels are measured and reported.
Access your report
Results are delivered securely online for you and your clinician to review.
Your Results Explained
Low Levels
Low faecal elastase levels indicate pancreatic exocrine insufficiency.
This suggests reduced enzyme production and impaired digestion.
Typical UK reference thresholds:
- <100 µg/g: Severe insufficiency
- 100–200 µg/g: Moderate insufficiency
Normal Levels
Normal elastase levels indicate adequate pancreatic enzyme production.
This makes pancreatic insufficiency unlikely.
High Levels
High levels are not usually clinically significant.
They indicate preserved pancreatic exocrine function.
How It Works
Simple steps to get your results
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.