1,25-dihydroxyvitamin D (calcitriol)
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Enhanced Liver Fibrosis
199.00
The Enhanced Liver Fibrosis test assesses liver scarring using advanced biomarkers. It helps identify and stage liver fibrosis without invasive procedures.
Turnaround time
2 weeks
Biomarkers count
1
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Enhanced Liver Fibrosis
What is the Enhanced Liver Fibrosis (ELF) test?
The Enhanced Liver Fibrosis (ELF) test is a specialised blood test that measures a combination of biomarkers associated with liver fibrosis, the process of scarring that occurs when the liver is repeatedly injured or inflamed.
The test analyses three key markers involved in extracellular matrix turnover and fibrotic activity: Hyaluronic Acid (HA), Procollagen III N-terminal peptide (PIIINP), and Tissue Inhibitor of Metalloproteinase-1 (TIMP-1). These are combined into a single ELF score.
Unlike liver biopsy, the ELF test is non-invasive, reproducible, and suitable for monitoring liver health over time.
Why do I need an Enhanced Liver Fibrosis test?
Liver fibrosis often develops silently and may progress to cirrhosis before symptoms appear. Early detection allows intervention before irreversible damage occurs.
You may need an ELF test if you:
- Have non-alcoholic fatty liver disease (NAFLD or MASLD)
- Have metabolic syndrome or insulin resistance
- Have type 2 diabetes
- Drink alcohol regularly or heavily
- Have chronic viral hepatitis
- Have abnormal liver function tests
- Need fibrosis risk assessment without biopsy
Conditions associated with liver fibrosis include:
- Fatty liver disease
- Chronic hepatitis B or C
- Alcohol-related liver disease
- Obesity-related liver inflammation
- Long-term medication-related liver injury
Benefits of the Enhanced Liver Fibrosis test
- Non-invasive fibrosis assessment
No biopsy required. - Detects early and advanced fibrosis
Identifies risk before cirrhosis develops. - Clinically validated liver score
Used in hepatology and metabolic medicine. - Suitable for monitoring progression
Tracks fibrosis changes over time. - Useful in fatty liver disease
Strong role in NAFLD/MASLD assessment. - Supports risk stratification
Helps guide referral and management. - Simple blood test
Minimal patient burden. - Avoids biopsy-related risks
No pain or procedural complications.
Step by step – how the test works
You can access Enhanced Liver Fibrosis testing UK-wide through two options:
- Clinic appointment
Attend your nearest UK clinic where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.
Your blood sample is analysed in an accredited UK laboratory and an ELF score is calculated.
Your results explained
Low ELF score – minimal fibrosis
Indicates little or no liver scarring.
Typical UK interpretation:
- ELF < 7.7
Moderate ELF score – developing fibrosis
Suggests ongoing fibrotic activity and increased risk.
Typical UK interpretation:
- ELF 7.7 – 9.8
High ELF score – advanced fibrosis
Indicates significant liver scarring with risk of progression to cirrhosis.
Typical UK interpretation:
- ELF > 9.8
Cut-offs may vary slightly by clinical guideline and population.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
In many cases, yes for risk stratification and monitoring.
It estimates fibrosis risk; imaging and clinical correlation may be needed.
Fasting is not usually required.
Yes. It is widely used in NAFLD/MASLD assessment.
Yes, in many cases with lifestyle and medical intervention.
As advised by your clinician, often annually or during monitoring.
Yes. Chronic alcohol use increases fibrosis risk.
Yes, especially in metabolic risk groups.
Yes. Home or hotel phlebotomy is available UK-wide for £60 extra.
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