What is the Essential TRT Baseline Panel?

The Essential TRT Baseline Panel is a focused blood test designed to establish a safe clinical starting point before beginning testosterone replacement therapy (TRT). It evaluates androgen status, pituitary signalling, prostate health, cardiovascular risk, liver function, and general blood health.

This panel includes the following biomarkers:

• Full Blood Count (FBC)

• Testosterone

• Free Testosterone

• Sex Hormone Binding Globulin (SHBG)

• Luteinising Hormone (LH)

• Follicle Stimulating Hormone (FSH)

• Oestradiol

• Total Prostate Specific Antigen (PSA)

• HbA1c (Glycated Haemoglobin)

• Lipid Profile

  • Total Cholesterol

  • Triglycerides

  • HDL Cholesterol

  • LDL Cholesterol

  • Cholesterol/HDL Ratio

  • Non-HDL Cholesterol

• Alanine Aminotransferase (ALT)

• Aspartate Aminotransferase (AST)

• Gamma-Glutamyl Transferase (GGT)

• Total Bilirubin

• Alkaline Phosphatase (ALP)

• Albumin

These markers provide a minimum safe dataset required before initiating or reviewing TRT.

Why do I need an Essential TRT Baseline Panel?

Starting TRT without adequate baseline testing increases the risk of complications such as erythrocytosis, prostate issues, lipid deterioration, or liver stress. This panel ensures testosterone therapy decisions are based on objective clinical evidence, not symptoms alone.

You may benefit from this test if you:

• Are considering starting TRT

• Have symptoms of low testosterone

• Want to confirm baseline hormone levels

• Need prostate safety screening

• Want to assess cardiovascular risk before TRT

• Are restarting TRT after a break

• Need documentation before specialist review

• Want safe, evidence-based hormone treatment

Benefits of the Essential TRT Baseline Panel

1. Confirms testosterone deficiency
   Measures both total and free testosterone.

2. Assesses pituitary signalling
   LH and FSH identify primary vs secondary hypogonadism.

3. Screens prostate safety
   PSA provides essential baseline risk assessment.

4. Evaluates cardiovascular risk
   Full lipid profile included.

5. Monitors liver function
   TRT can influence liver enzymes.

6. Assesses long-term glucose control
   HbA1c screens metabolic risk.

7. Establishes blood health baseline
   FBC detects elevated haemoglobin risk.

8. Supports safe TRT initiation
   Reduces avoidable complications.

Step-by-step – how we offer Essential TRT Baseline testing

Clinic-based testing (UK-wide)

• Choose your nearest UK clinic

• Attend your appointment

• Blood samples collected by a qualified clinician or phlebotomist

• Samples sent to the laboratory for analysis

At-home or hotel testing (+£60)

• A qualified phlebotomist visits your home or hotel

• Blood samples collected in a comfortable setting

• No clinic visit required

Both services are available UK-wide.

Your Essential TRT Baseline results explained

Results indicating low testosterone

Low total or free testosterone with abnormal LH/FSH suggests hypogonadism. This helps identify whether the issue is testicular or pituitary in origin.

UK reference interpretation:

• Low: Below laboratory reference ranges

Results within acceptable baseline ranges

Normal hormone levels, stable PSA, healthy lipids, and normal blood counts suggest a suitable baseline for TRT consideration.

UK reference interpretation:

• Normal: Within laboratory reference ranges

Results requiring caution or further review

Elevated PSA, abnormal lipids, raised liver enzymes, or high haemoglobin may require optimisation or specialist input before TRT.

UK reference interpretation:

• Abnormal: Above laboratory reference ranges