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Gamma-Glutamyltransferase

Organ Function & Health
28.00

This test measures GGT, an enzyme linked to liver and bile duct function. It helps detect liver stress and alcohol-related damage.

Turnaround time

1-2 days

Biomarkers count

1

Same-Day Appointments
UKAS Accredited Labs

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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Gamma-Glutamyltransferase

GGT Blood Test | London Blood Tests UK

Check liver and bile duct health with our GGT blood test from £28. UKAS-accredited testing, fast results, optional GP consultation available.

The Gamma-Glutamyltransferase (GGT) Blood Test measures GGT enzyme levels to assess liver function, bile duct health, and potential alcohol-related liver stress. Available for £28, analysed in a UKAS-accredited laboratory, with results typically ready within 1–2 business days and an optional GP consultation for interpretation.

 

What is a Gamma-Glutamyltransferase (GGT) Test?

Gamma-Glutamyltransferase (GGT) is an enzyme found predominantly in the liver, bile ducts, and pancreas. It plays a role in amino acid transport and glutathione metabolism — a key antioxidant system involved in detoxification.

When liver cells or bile ducts are damaged or stressed, GGT is released into the bloodstream. Elevated GGT levels often indicate cholestasis (impaired bile flow), liver inflammation, or toxic liver stress, particularly from alcohol or certain medications.

GGT is frequently measured alongside other liver enzymes such as ALT, AST, ALP, and bilirubin to provide a comprehensive picture of liver health. It is especially helpful in distinguishing liver-related causes of elevated alkaline phosphatase (ALP).

 

Benefits of the GGT Blood Test

  1. Sensitive Marker of Liver Stress
    GGT often rises earlier than other liver enzymes, making it a sensitive indicator of liver strain.

  2. Detects Alcohol-Related Liver Damage
    Particularly useful for identifying excessive alcohol intake or monitoring liver recovery after abstinence.

  3. Assesses Bile Duct Function
    Elevated GGT alongside ALP suggests bile duct obstruction or cholestatic liver disease.

  4. Supports Medication Safety Monitoring
    Helps monitor liver effects of long-term medication use, including anticonvulsants and statins.

  5. Differentiates Liver vs Bone ALP Elevation
    A normal GGT with raised ALP suggests bone rather than liver pathology.

  6. Useful for Lifestyle & Detox Monitoring
    Tracks improvements in liver health following dietary changes or alcohol reduction.

  7. Optional GP Consultation for Interpretation
    Results can be reviewed with a GP to guide lifestyle changes or further investigations.

 

Why Do I Need a GGT Blood Test?

You may benefit from GGT testing if you have:

  • Regular or heavy alcohol consumption

  • Fatigue or unexplained weakness

  • Abdominal discomfort or bloating

  • Abnormal liver enzymes on previous tests

  • Long-term medication use affecting the liver

  • Suspected fatty liver disease

  • Monitoring during alcohol reduction programs

GGT testing is also valuable when ALP is elevated and the cause needs clarification.

 

How the Test Works

In-Clinic Blood Test

  1. Book Your Appointment

    • Book online or by phone — no referral required.

  2. Pre-Test Preparation

    • No fasting required (unless combined with other tests).

    • Avoid alcohol for 24–48 hours before testing if possible.

  3. Blood Sample Collection

    • A trained phlebotomist collects a venous blood sample.

    • The procedure takes around 5 minutes.

  4. Sample Handling

    • The sample is transported to a UKAS-accredited laboratory.

  5. Laboratory Analysis

    • GGT is measured using enzymatic spectrophotometric methods.

  6. Quality Control

    • Strict internal and external checks ensure accuracy.

  7. Results Delivery

    • Results are typically available within 1–2 business days.

  8. Optional GP Consultation

    • Discuss abnormal results and next steps with a GP if required.

At-Home Blood Draw (Home or Hotel Service)

  1. Book a Home Visit

    • Choose a convenient UK-wide location.

  2. Professional Phlebotomist Visit

    • A certified phlebotomist attends your home or hotel.

  3. Blood Collection

    • A venous blood sample is collected safely.

  4. Courier to Laboratory

    • The sample is transported the same day.

  5. Analysis & Reporting

    • GGT levels are analysed promptly.

  6. Optional GP Review

    • Results can be reviewed with a GP if needed.

 

Your GGT Test Results – Explained

GGT levels are reported in U/L (units per litre).

Typical UK Reference Ranges

  • Men: 8–61 U/L

  • Women: 5–36 U/L

Interpretation

  • Normal GGT
    Suggests healthy liver and bile duct function.

  • Mildly Elevated GGT
    May reflect alcohol intake, fatty liver, or medication effects.

  • Markedly Elevated GGT
    Suggests liver disease, bile duct obstruction, or chronic alcohol exposure.

GGT should always be interpreted alongside ALT, AST, ALP, and clinical history.

How It Works

Simple steps to get your results

1

Book Online

Choose your test online and book in seconds. Select your preferred clinic location or home visit option.

2

Visit or Test at Home

Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.

3

Get Your Results

Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.

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How to Prepare for Your Test

Follow these guidelines for accurate results

Sample Timing

Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.

Fasting & Hydration

Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.

Medications & Supplements

Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.

Hormones & Menstrual Cycle

For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.

If you have any questions or special circumstances, our team is happy to advise before your appointment.

Frequently Asked Questions

It measures gamma-glutamyltransferase, an enzyme released during liver or bile duct stress.

No — while alcohol commonly raises GGT, medications and liver disease can also elevate it.

No fasting is required.

Yes — anticonvulsants, statins, and some antibiotics can increase levels.

GGT responds within days to weeks after lifestyle or alcohol changes.

Yes — GGT often rises early in non-alcoholic fatty liver disease.

Results are typically ready within 1–2 business days.

Yes — via clinic testing or at-home phlebotomy services.

Ideally yes — abstain for 24–48 hours to avoid transient elevation.

An optional GP consultation is recommended for abnormal results.

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