1,25-dihydroxyvitamin D (Calcitriol)
This test measures 1,25-dihydroxyvitamin D, the biologically active form of vitamin D. It is used to investigate calcium imbalance, kidney disease and...
Genetic Bowel Cancer Risk
550.00
This test detects genetic variants associated with inherited risk of bowel cancer. It supports early screening and preventive strategies for individuals with increased genetic risk.
Turnaround time
4-6 weeks
Biomarkers count
11
Same-Day Appointments
UKAS Accredited Labs
Book your test
Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
1
Email
2
Service
3
Details
4
Confirm
{{ emailError }}
Choose Service Type
Home visit
Professional phlebotomist comes to you
+ £{{ home_visit_fee }}
In clinic
Visit our clinic for your test
{{ clinic_visit_fee > 0 ? '+ £' + clinic_visit_fee : 'Free' }}
Home Visit Details
{{ homeAddressError }}
Home visits require at least 24 hours notice.
{{ homeTimeError }}
Choose Clinic Option
Select a clinic:
{{ clinic.name }}
{{ clinic.full_address }}
{{ selectedClinic.name }}
{{ selectedClinic.full_address }}
Select a date
{{ timeSlotAlert }}
Select an hour
Available time slots: {{ timeSlots.length}}
{{ slot.preview }}
{{ selectedTime.preview }}
Loading add-ons...
{{ addOnError }}
No recommended add-ons available.
×
{{ addon.name }}
£{{ addon.price }}
{{ addon.excerpt }}
Selected
Selected ({{ selectedAddOns.length }})
£{{ addOnsTotal }}
- {{ sa.name }} £{{ sa.price }}
Included in total above.
Details about Genetic Bowel Cancer Risk
Genetic Bowel Cancer Risk | London Blood Tests |
At London Blood Tests, we provide advanced genetic testing services to help you understand and manage your health risks. Our Genetic Bowel Cancer Risk Test screens for genetic variants associated with an increased risk of bowel cancer and Lynch Syndrome. This test provides valuable insights into your genetic predisposition, allowing you to take proactive measures in managing your health.
What is it?
Our Genetic Bowel Cancer Risk Test screens and detects genetic variants in 11 genes that may increase the risk of bowel cancer and Lynch Syndrome. The genes analyzed include APC, BMPR1A, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, SMAD4, and STK11.
1. APC: Tumor suppressor gene involved in controlling cell growth. Mutations cause familial adenomatous polyposis (FAP), leading to a high risk of colon cancer.
2. BMPR1A: Involved in cell growth and development. Mutations can cause juvenile polyposis syndrome, increasing the risk of gastrointestinal cancers.
3. EPCAM: Affects cell adhesion and signaling. Mutations can lead to Lynch syndrome (via MSH2 inactivation), increasing the risk of colon and other cancers.
4. MLH1: Involved in DNA mismatch repair. Mutations cause Lynch syndrome, leading to a higher risk of colorectal and other cancers.
5. MSH2: Another gene involved in DNA mismatch repair. Mutations are a common cause of Lynch syndrome, with increased cancer risks.
6. MSH6: Also involved in DNA mismatch repair. Mutations increase the risk of Lynch syndrome, though typically with a later onset than MLH1 or MSH2 mutations.
7. MUTYH: Involved in DNA repair, specifically fixing oxidative damage. Mutations cause MUTYH-associated polyposis (MAP), increasing colorectal cancer risk.
8. PMS2: A DNA mismatch repair gene. Mutations can cause Lynch syndrome, contributing to a higher risk of colorectal and other cancers.
9. PTEN: Tumor suppressor gene that regulates cell growth. Mutations cause Cowden syndrome, increasing the risk of breast, thyroid, and other cancers.
10. SMAD4: Involved in signal transduction and regulating cell growth. Mutations cause juvenile polyposis syndrome, increasing gastrointestinal cancer risk.
11. STK11: Tumor suppressor gene involved in regulating cell growth. Mutations cause Peutz-Jeghers syndrome, leading to an increased risk of gastrointestinal and other cancers.
Benefits
• Accurate Risk Assessment: Identify your genetic predisposition to bowel cancer and Lynch Syndrome.
• Proactive Health Management: Take informed steps to monitor and manage cancer risk proactively.
• Detailed Genetic Analysis: Receive a comprehensive report detailing your genetic profile and potential risks.
• Quick Turnaround: Receive your results within 6 weeks, allowing for timely medical advice and action.
The Process
• Book an Appointment: Schedule your test online or via phone.
• Sample Collection: Visit our clinic for a blood sample collection or arrange a home visit for an additional £60.
• Laboratory Analysis: Our expert team analyzes your sample for the specified genetic variants.
• Receive Results: Get your results within 6 weeks, complete with a detailed report and personalized recommendations.
Why Choose London Blood Tests?
• Experienced Professionals: Our team of specialists ensures precise and reliable testing.
• Convenient Locations: Easily accessible clinics across London.
• Comprehensive Support: From booking to results, we provide support at every step.
Ideal For
• Individuals diagnosed with bowel cancer or Lynch Syndrome-related cancer.
• Those with a family history of bowel cancer or Lynch Syndrome.
• Anyone seeking to understand their genetic risk for bowel cancer and Lynch Syndrome.
How to Get Started
1. Schedule Your Test: Book online or call us to arrange your test.
2. Choose Your Collection Method: Decide between a clinic visit or a home visit for an additional fee.
3. Prepare for the Test: Follow any pre-test instructions provided.
4. Get Tested: Visit the clinic or have a professional come to your home to collect your sample.
5. Receive Your Results: We will send your results via email within 6 weeks.
Understanding your genetic risk for bowel cancer and Lynch Syndrome can significantly enhance your ability to manage and reduce risk effectively. At London Blood Tests, we offer a thorough and reliable Genetic Bowel Cancer Risk Test to help you take control of your health. Book your test today and take the first step towards proactive health management.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
No. It identifies inherited risk, not active disease.
No. It is designed for proactive risk assessment.
Yes. Your genetic profile does not change.
Yes. Cascade screening is recommended if a mutation is found.
Yes. It may lead to earlier and more frequent colonoscopies.
Yes. Many people test proactively due to family history.
Yes. At-home phlebotomy is available across the UK.
Performed in UKAS-accredited laboratories using clinical-grade sequencing.
Typically 14–21 business days.
A GP consultation is optional, but strongly recommended for positive results.
Similar Products in Blood Testing
Discover more options in this category:
17-Hydroxyprogesterone
This test measures 17-hydroxyprogesterone, a hormone involved in cortisol production. It is used to assess adrenal function and diagnose congenital ad...
5 HIAA
The 5-HIAA (5-Hydroxyindoleacetic Acid) blood test measures the amount of 5-HIAA, a breakdown product of serotonin, in the bloodstream. Elevated level...
6-Thioguanine Nucleotides
This test measures 6-thioguanine nucleotide levels to monitor thiopurine medications. It helps optimise treatment effectiveness while reducing toxicit...
7 Sexually Transmitted Infections by PCR
This PCR screen detects seven common sexually transmitted infections with high accuracy. It identifies active infections even when symptoms are mild o...