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Genetic Full Cancer Risk
820.00
This test analyses multiple genetic variants associated with inherited risk across several cancer types. It helps guide personalised screening and preventive strategies based on genetic susceptibility.
Turnaround time
4-6 weeks
Biomarkers count
91
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Genetic Full Cancer Risk
Genetic Full Cancer Risk | London Blood Tests |
At London Blood Tests, we provide comprehensive genetic testing services to help you understand and manage your health risks. Our Genetic Full Cancer Risk Test screens for genetic variants associated with an increased risk of both common and rare cancers. This test offers valuable insights into your genetic predisposition, allowing you to take proactive measures in managing your health.
What is it?
Our Genetic Full Cancer Risk Test comprehensively screens and detects genetic variants in 94 genes that may increase the risk of common and rare cancers. The genes analyzed include AIP, ALK, APC, ATM, BAP1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, BUB1B, CDC73, CDH1, CDK4, CDKN1C, CDKN2A, CEBPA, CEP57, CHEK2, CYLD, DDB2, DICER1, DIS3L2, EGFR, EPCAM, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, EZH2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FH, FLCN, GATA2, GPC3, HNF1A, HRAS, KIT, MAX, MEN1, MET, MLH1, MSH2, MSH6, MUTYH, NBN, NF1, NF2, NSD1, PALB2, PHOX2B, PMS1, PMS2, PRF1, PRKAR1A, PTCH1, PTEN, RAD51C, RAD51D, RB1, RECQL4, RET, RHBD, RUNX1, SBDS, SDHA, SDHAF2, SDHB, SDHC, SDHD, SLX4, SMAD4, SMARCB1, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, WRN, WT1, XPA, XPC.
1. Tumor Suppressor Genes
These genes normally prevent uncontrolled cell growth. Mutations can lead to various cancers.
· APC: Familial adenomatous polyposis, colorectal cancer
· BAP1: Uveal melanoma, mesothelioma
· BMPR1A: Juvenile polyposis syndrome
· BRCA1, BRCA2: Breast and ovarian cancer
· CDC73: Hyperparathyroidism-jaw tumor syndrome
· CDH1: Hereditary diffuse gastric cancer, lobular breast cancer
· CDKN2A: Melanoma, pancreatic cancer
· CYLD: Cylindromatosis, skin tumors
· DICER1: DICER1 syndrome, various childhood cancers
· EXT1, EXT2: Hereditary multiple exostoses, bone tumors
· FH: Hereditary leiomyomatosis and renal cell cancer
· FLCN: Birt-Hogg-Dubé syndrome, kidney cancer
· MAX: Hereditary pheochromocytoma and paraganglioma
· MEN1: Multiple endocrine neoplasia type 1
· NF1: Neurofibromatosis type 1, benign tumors
· NF2: Neurofibromatosis type 2, benign tumors
· PTEN: Cowden syndrome, breast, thyroid, and other cancers
· RB1: Retinoblastoma
· SDHA, SDHAF2, SDHB, SDHC, SDHD: Paragangliomas, pheochromocytomas
· SMARCB1: Malignant rhabdoid tumors
· STK11: Peutz-Jeghers syndrome, gastrointestinal and other cancers
· TP53: Li-Fraumeni syndrome, multiple cancers
· TSC1, TSC2: Tuberous sclerosis, benign tumors
· VHL: von Hippel-Lindau syndrome, kidney cancer
· WT1: Wilms tumor, childhood kidney cancer
2. DNA Repair Genes
These genes are involved in fixing DNA damage. Mutations increase the risk of various cancers.
· ATM: Breast cancer, Ataxia-telangiectasia
· BRIP1: Ovarian cancer
· CHEK2: Breast and other cancers
· ERCC2, ERCC3, ERCC4, ERCC5: Xeroderma pigmentosum, skin cancer
· FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM: Fanconi anemia, leukemia, and other cancers
· MLH1, MSH2, MSH6, PMS1, PMS2: Lynch syndrome, colorectal and other cancers
· MUTYH: MUTYH-associated polyposis, colorectal cancer
· NBN: Nijmegen breakage syndrome, cancer risk
· PALB2: Breast cancer
· RAD51C, RAD51D: Breast and ovarian cancer
· RECQL4: Rothmund-Thomson syndrome, cancer risk
· SLX4: Fanconi anemia-like syndrome, cancer risk
· WRN: Werner syndrome, cancer and aging
· XPA, XPC: Xeroderma pigmentosum, skin cancer
3. Genes Involved in Cell Cycle Regulation
These genes control cell division. Mutations can lead to cancer.
· BUB1B: Mosaic variegated aneuploidy syndrome, cancer risk
· CDK4: Familial melanoma
· CDKN1C: Beckwith-Wiedemann syndrome, cancer risk
· CEBPA: Familial acute myeloid leukemia
· CEP57: Mosaic variegated aneuploidy syndrome, cancer risk
· PRKAR1A: Carney complex, multiple endocrine tumors
4. Oncogenes
· These genes, when mutated or overexpressed, can promote cancer.
· ALK: Lung cancer, neuroblastoma
· EGFR: Lung cancer, other cancers
· HRAS: Costello syndrome, increased cancer risk
· KIT: Gastrointestinal stromal tumors (GIST)
· KRAS: Various cancers
· RET: Multiple endocrine neoplasia type 2, medullary thyroid cancer
· MET: Hereditary papillary renal carcinoma
· RHBD: Increased cancer risk
5. Genes Related to Specific Syndromes and Conditions
These genes are associated with specific genetic syndromes that carry a cancer risk.
· AIP: Pituitary adenomas
· DIS3L2: Perlman syndrome, cancer risk
· EZH2: Various cancers, especially lymphoma
· GATA2: GATA2 deficiency, blood cancers
· GPC3: Simpson-Golabi-Behmel syndrome, cancer risk
· HNF1A: Maturity-onset diabetes of the young (MODY), cancer risk
· PHOX2B: Congenital central hypoventilation syndrome, cancer risk
· PRF1: Familial hemophagocytic lymphohistiocytosis, immune-related cancers
· RUNX1: Familial platelet disorder with associated myeloid malignancies
· SBDS: Shwachman-Diamond syndrome, cancer risk
· SMAD4: Juvenile polyposis syndrome, gastrointestinal cancers
· SUFU: Gorlin syndrome, basal cell carcinoma
6. Genes Related to Gene Expression and Epigenetic Regulation
These genes regulate gene expression or epigenetic modifications, and mutations can lead to cancer.
· DDB2: DNA repair, skin cancer risk
· EZH2: Gene silencing, linked to cancer, especially lymphoma
· NSD1: Sotos syndrome, increased cancer risk
· SMARCB1: Regulates chromatin structure, associated with rhabdoid tumors
Benefits
• Comprehensive Risk Assessment: Identify your genetic predisposition to a wide range of common and rare cancers.
• Proactive Health Management: Take informed steps to monitor and manage cancer risk proactively.
• Detailed Genetic Analysis: Receive a comprehensive report detailing your genetic profile and potential risks.
• Quick Turnaround: Receive your results within 6 weeks, allowing for timely medical advice and action.
The Process
• Book an Appointment: Schedule your test online or via phone.
• Sample Collection: Visit our clinic for a blood sample collection or arrange a home visit for an additional £60.
• Laboratory Analysis: Our expert team analyzes your sample for the specified genetic variants.
• Receive Results: Get your results within 6 weeks, complete with a detailed report and personalized recommendations.
Why Choose London Blood Tests?
• Experienced Professionals: Our team of specialists ensures precise and reliable testing.
• Convenient Locations: Easily accessible clinics across London.
• Comprehensive Support: From booking to results, we provide support at every step.
Ideal For
• Individuals diagnosed with cancer.
• Those with a family history of common or rare cancer types.
• Patients with no previous variants detected on a smaller gene panel.
• Anyone seeking to understand their genetic risk for cancer.
How to Get Started
1. Schedule Your Test: Book online or call us to arrange your test.
2. Choose Your Collection Method: Decide between a clinic visit or a home visit for an additional fee.
3. Prepare for the Test: Follow any pre-test instructions provided.
4. Get Tested: Visit the clinic or have a professional come to your home to collect your sample.
5. Receive Your Results: We will send your results via email within 6 weeks.
Understanding your genetic risk for cancer can significantly enhance your ability to manage and reduce risk effectively. At London Blood Tests, we offer a thorough and reliable Genetic Full Cancer Risk Test to help you take control of your health. Book your test today and take the first step towards proactive health management.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
No. It identifies inherited risk, not active disease.
Yes. It is designed for proactive risk assessment.
Yes. Your genetic profile does not change.
Yes, if a pathogenic mutation is identified.
Yes. Results may alter screening type and start age.
Yes. It is suitable for all genders.
Yes. At-home phlebotomy is available across the UK.
Testing is performed in UKAS-accredited laboratories using clinical-grade sequencing.
Typically 14–21 business days.
A GP consultation is optional, but strongly recommended for positive results.
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