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Genetic Coeliac Disease Test
199.00
This test checks genes linked to coeliac disease risk. It helps rule out or support genetic susceptibility to gluten intolerance.
Turnaround time
4-6 weeks
Biomarkers count
3
Same-Day Appointments
UKAS Accredited Labs
Book your test
Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Genetic Coeliac Disease Test
At London Blood Tests, we provide advanced diagnostic services to help you manage and understand your health conditions. Our Genetic Coeliac Disease Test is designed to identify genetic markers associated with coeliac disease, enabling you to take proactive steps in managing your diet and health. If you experience symptoms related to coeliac disease, this test can offer the insights needed to confirm a diagnosis and guide your treatment plan.
What is it?
Our Genetic Coeliac Disease Test involves genotyping for HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8. These markers are present in up to 99.7% of all coeliac disease patients, making it a highly reliable test for identifying genetic predispositions to this condition.
The HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8 are specific variants (alleles) of the human leukocyte antigen (HLA) system, which is part of the immune system. These particular HLA types are strongly associated with celiac disease, an autoimmune disorder where ingestion of gluten leads to damage in the small intestine.
1. HLA-DQ2.2: This allele is one of the variants associated with an increased risk of celiac disease, although it confers a lower risk compared to HLA-DQ2.5. Individuals with this allele may develop celiac disease, but it is less common.
2. HLA-DQ2.5: This is the most common and most strongly associated allele with celiac disease. About 90-95% of people with celiac disease carry HLA-DQ2.5. It significantly increases the risk of developing the disease when exposed to gluten.
3. HLA-DQ8: This allele is also associated with celiac disease, but less frequently than HLA-DQ2.5. It is found in about 5-10% of individuals with celiac disease, and those who carry it still have a risk of developing the disease when exposed to gluten.
These HLA variants are important markers used in the genetic testing for celiac disease risk. However, carrying one of these alleles does not guarantee that a person will develop celiac disease; it simply indicates a genetic predisposition.
Benefits
• Accurate Diagnosis: Identify your genetic risk for coeliac disease.
• Proactive Health Management: Take informed steps to manage your diet and prevent complications.
• Quick Results: Receive your results within 7 days, allowing for timely medical advice and action.
The Process
• Book an Appointment: Schedule your test online or via phone.
• Sample Collection: Visit our clinic for a blood sample collection or arrange a home visit for an additional £60.
• Laboratory Analysis: Our expert team analyzes your sample for HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8 markers.
• Receive Results: Get your results within 7 days, complete with a detailed report and recommendations.
Why Choose London Blood Tests?
• Experienced Professionals: Our team of specialists ensures precise and reliable testing.
• Convenient Locations: Easily accessible clinics across London.
• Comprehensive Support: From booking to results, we provide support at every step.
Ideal For
• Individuals exhibiting symptoms of coeliac disease such as chronic diarrhoea, abdominal pain, bloating, and fatigue.
• Those with a family history of coeliac disease.
• Anyone seeking to confirm a coeliac disease diagnosis through genetic testing.
How to Get Started
1. Schedule Your Test: Book online or call us to arrange your test.
2. Choose Your Collection Method: Decide between a clinic visit or a home visit for an additional fee.
3. Prepare for the Test: Follow any pre-test instructions provided.
4. Get Tested: Visit the clinic or have a professional come to your home to collect your sample.
5. Receive Your Results: We will send your results via email within 7 days.
Understanding your genetic risk for coeliac disease can significantly enhance your quality of life by allowing you to make informed dietary choices. At London Blood Tests, we offer a quick, reliable, and convenient way to diagnose genetic predispositions to coeliac disease. Book your test today and take the first step towards better health management.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
No. It identifies genetic risk, not active disease.
Yes. Gluten consumption is not required.
It complements antibody testing but answers a different question.
Yes. Your genetic status does not change.
Yes. It can be performed at any age.
Possibly, depending on symptoms and clinical context.
Yes. At-home phlebotomy is available across the UK.
Testing is performed in UKAS-accredited laboratories using validated genetic methods.
Results are usually available within 10–14 business days.
A GP consultation is optional, but recommended for result interpretation.
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