[email protected] +44 203 488 0809

AI Assistant

Gluten Allergy Profile

Allergy Testing

536.00

A six-marker gluten profile combining specific IgE, coeliac serology, Total IgA and HLA-DQ2/DQ8 genetics to distinguish different immune pathways.

Turnaround time

2 weeks

Biomarkers count

6

Enhance Your Panel

{{ availableAddOns.length }} extra tests · sorted by relevance

×

No tests match "{{ addOnSearch }}"

{{ selectedAddOns.length }} test{{ selectedAddOns.length !== 1 ? 's' : '' }} added +£{{ addOnsTotal.toFixed(2) }}

Same-Day Appointments

UKAS Accredited Labs

Book your test

Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.

1

Email

2

Service

3

Details

4

Confirm

{{ emailError }}

Choose Service Type

Home visit

Professional phlebotomist comes to you

+ £{{ home_visit_fee }}

In clinic

Visit our clinic for your test

{{ clinic_visit_fee > 0 ? '+ £' + clinic_visit_fee : 'Free' }}

Home Visit Details

{{ homeAddressError }}

Home visits require at least 24 hours notice.

{{ homeTimeError }}

Note: Home visits are not available on Sundays

Select a clinic: Sorting by distance…

{{ clinic.name }}

{{ clinicAddress(clinic) }}

{{ clinic.distance.toFixed(1) }} mi

{{ selectedClinic.name }}

{{ clinicAddress(selectedClinic) }}

Select a date

{{ timeSlotAlert }}

Note: Bookings are not available on Sundays

Select an hour

Available time slots: {{ timeSlots.length}}

{{ selectedAddOns.length }} extra test{{ selectedAddOns.length !== 1 ? 's' : '' }} added +£{{ addOnsTotal.toFixed(2) }}

I agree to my blood being taken / sampled

Please confirm your consent before proceeding.

Overview of the Gluten Allergy Profile Test

The Gluten Allergy Profile is a six-marker blood profile combining specific IgE allergy testing, coeliac serology, Total IgA and genetic susceptibility testing.

Gluten-related symptoms can arise through different mechanisms.

Coeliac disease is an autoimmune condition.

An immediate IgE-mediated reaction represents a different immune pathway.

Genetic HLA susceptibility provides information about whether the genetic background associated with coeliac disease is present but does not diagnose active disease.

The profile combines these distinct investigations within one test to provide a broader assessment than Gluten-specific IgE or Tissue Transglutaminase alone.

The six markers are Gluten-specific IgE, Endomysial IgA, Deamidated Gliadin IgG, Tissue Transglutaminase IgA, HLA-DQ2/DQ8 Genotype and Total IgA.

The Gluten Allergy Profile costs £536.

What Does the Gluten Allergy Profile Test Check?

This test measures 6 biomarkers across allergy, autoimmune coeliac serology, immune status and genetic susceptibility.

Coeliac Disease - HLA DQ2/DQ8 Genotype

Assesses major HLA genetic susceptibility associated with coeliac disease.

Deamidated Gliadin IgG Antibodies

Measures IgG antibodies to deamidated Gliadin peptides and can provide useful coeliac-related serological information.

Endomysial Antibodies IgA

Detects IgA antibodies strongly associated with coeliac disease when interpreted appropriately.

Gluten Single IgE Allergen

Measures specific IgE sensitisation to Gluten and assesses an immediate-type allergy pathway rather than autoimmune coeliac disease.

Tissue Transglutaminase IgA

Measures tTG IgA, one of the principal serological markers used during coeliac assessment.

Total IgA

Measures overall Immunoglobulin A concentration and helps assess whether IgA-based coeliac serology can be interpreted reliably.

Who May Benefit From the Gluten Allergy Profile Test?

The profile may be useful when gluten-related symptoms are present but it is unclear whether allergy, coeliac disease or genetic susceptibility may be relevant.

People with digestive symptoms after eating gluten-containing foods - Several immune pathways are assessed.

People with suspected coeliac disease - tTG IgA, Endomysial IgA and Deamidated Gliadin IgG are included.

People with possible immediate allergic reactions to gluten-containing foods - Gluten-specific IgE is included.

People with a family history of coeliac disease - HLA-DQ2/DQ8 genetic susceptibility is assessed.

People with unexplained Iron deficiency or nutritional problems - Coeliac disease can affect nutrient absorption.

People with previous incomplete or conflicting gluten-related test results - The profile brings several different investigations together.

How to Prepare

Fasting

Fasting is not normally required.

Hydration

Drink water normally before testing.

Medication

Continue prescribed medication unless advised otherwise.

Supplements

Tell us about Iron, Folate, Vitamin B12 and other nutritional supplements.

Alcohol

No specific alcohol restriction is normally required.

Exercise

Avoid unusually strenuous exercise immediately before testing where possible.

Gluten intake

Continue consuming gluten before coeliac antibody testing unless your clinician has specifically advised otherwise.

Diet

Do not deliberately consume a food that has previously caused a serious immediate allergic reaction simply for testing purposes.

The HLA-DQ2/DQ8 genetic component remains valid regardless of current gluten intake.

However, reducing or eliminating gluten can lower coeliac antibody concentrations and potentially affect serology.

Symptoms and Reasons to Consider the Gluten Allergy Profile Test

Gluten-related symptoms can vary and are not specific to one condition.

Bloating or abdominal discomfort after gluten-containing foods - Coeliac disease is one of several possible causes.

Persistent diarrhoea or altered bowel habit - Gastrointestinal investigation may be appropriate.

Unexplained Iron-deficiency anaemia - Coeliac disease can impair nutrient absorption.

Skin symptoms compatible with gluten-related disease - Appropriate clinical assessment may be required.

Immediate itching, swelling or allergic-type symptoms after exposure - IgE-mediated allergy should be assessed separately from coeliac disease.

Family history of coeliac disease - Genetic susceptibility testing can provide additional information.

Persistent fatigue or nutritional deficiency - Malabsorption is one possible explanation among many.

Breathing difficulty, throat swelling, collapse or a rapidly progressing allergic reaction requires emergency medical care.

Coeliac disease and IgE-mediated allergy are different conditions and their test results should not be treated as interchangeable.

How to Book Your Gluten Allergy Profile Test

The Gluten Allergy Profile can be booked as a specialist private blood test combining serological, allergy and genetic investigations.

1

Choose the Gluten Allergy Profile

Select the £536 six-marker profile.

2

Select your collection

Choose in-clinic phlebotomy (+£35) or a home visit from a phlebotomist (+£60).

3

Attend your appointment

A trained healthcare professional collects the required blood specimens.

4

Laboratory analysis

Specific IgE, coeliac antibodies, Total IgA and HLA-DQ2/DQ8 genotype are assessed.

5

Receive your results securely

Your completed Gluten Allergy Profile is delivered securely.

When Will I Receive My Results?

Results are generally expected within approximately 2 weeks.

The genetic component contributes to the longer reporting time compared with routine coeliac serology alone.

Understanding Your Results

The six markers assess different mechanisms and should be interpreted separately.

A positive Gluten-specific IgE result demonstrates sensitisation but does not automatically establish clinical allergy.

Positive tTG IgA or Endomysial IgA can support investigation for coeliac disease but require appropriate clinical interpretation.

Total IgA helps identify situations in which IgA-based coeliac tests may be less reliable.

HLA-DQ2/DQ8 indicates genetic susceptibility and does not diagnose active coeliac disease.

A positive genetic result can occur in people who never develop coeliac disease.

Why Book With London Blood Tests?

London Blood Tests provides a broad gluten-related profile combining several different diagnostic pathways.

Six targeted biomarkers - Allergy, coeliac antibodies, immune status and genetics are assessed.

Gluten-specific IgE included - Immediate-type allergic sensitisation is investigated.

Key coeliac antibodies included - tTG IgA, Endomysial IgA and Deamidated Gliadin IgG are measured.

Total IgA included - This helps assess reliability of IgA-based coeliac serology.

HLA-DQ2/DQ8 genetics included - Genetic susceptibility can be assessed even when gluten has already been reduced.

Professional blood collection - Specialist specimen requirements are handled appropriately.

Clear pricing - The Gluten Allergy Profile costs £536.

Private Gluten Allergy Profile Blood Test in London

London Blood Tests provides the Gluten Allergy Profile for £536.

The profile contains six biomarkers combining specific IgE, coeliac serology, Total IgA and HLA-DQ2/DQ8 genetic assessment.

The expected turnaround is approximately two weeks.

Frequently Asked Questions

It measures five antibody markers associated with Chlamydia pneumoniae, Mycoplasma pneumoniae and Legionella.

The profile contains five measurements: Chlamydia Pneumoniae IgG, Chlamydia Pneumoniae IgM, Legionella Ab Screening, Mycoplasma pnemoniae IgM and Mycoplasma pneumoniae IgG.

Atypical pneumonia is a term commonly used for pneumonia caused by certain organisms, including Mycoplasma pneumoniae, Chlamydia pneumoniae and Legionella, which may produce a somewhat different clinical pattern from some other bacterial pneumonias.

IgM may appear earlier during an immune response, while IgG commonly develops later and can remain detectable after previous infection. Neither should be interpreted independently of symptoms and timing.

Yes. IgG antibodies can persist after previous exposure, so a positive IgG result does not necessarily mean you currently have an active respiratory infection.

No. The test measures antibodies and cannot independently confirm active pneumonia. Clinical examination, imaging and direct microbiological testing may also be required.

Yes. Antibodies may not yet be detectable if the sample is collected early, and not every infected person develops the same antibody response.

No fasting is normally required for this test unless you are having another blood test at the same appointment that requires fasting.

The expected turnaround is approximately 7 business days from laboratory receipt of the sample, although specialist analysis may occasionally take longer.

Yes. London Blood Tests offers in-clinic blood collection and home or hotel phlebotomy for an additional £60 depending on location and availability. A GP consultation is not included and can be arranged separately.