H. pylori Antigen (Stool)
The H. pylori stool antigen test detects active Helicobacter pylori infection. It is used for diagnosis and to confirm successful eradication after treatment.
Turnaround time
1 day
Biomarkers count
1
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Details about H. pylori Antigen (Stool)
What is the H. pylori Antigen (Stool) test?
The H. pylori Antigen (Stool) test is a non-invasive diagnostic test that detects Helicobacter pylori antigens in a stool sample. Unlike antibody blood tests, this method identifies active infection, not just past exposure.
H. pylori is a bacterium that colonises the stomach lining and causes chronic inflammation. Detecting its antigens in stool confirms that the organism is currently present and metabolically active in the gastrointestinal tract.
This test is widely recommended as a first-line diagnostic tool and is also the preferred method for confirming eradication after treatment.
Why do I need an H. pylori Antigen test?
Active H. pylori infection is a major cause of gastritis, peptic ulcer disease, and long-term stomach complications. Accurate diagnosis allows prompt treatment and reduces future risk.
You may need this test if you:
- Have persistent upper abdominal pain
- Experience bloating, nausea or indigestion
- Have recurrent heartburn or reflux
- Have a history of gastric or duodenal ulcers
- Have unexplained iron-deficiency anaemia
- Are being assessed for chronic gastritis
- Need confirmation after H. pylori treatment
Symptoms commonly associated with active H. pylori infection include:
- Burning or gnawing stomach pain
- Nausea
- Bloating
- Loss of appetite
- Early fullness
- Unexplained weight loss
Benefits of the H. pylori Antigen (Stool) test
- Detects active infection
Confirms current H. pylori presence. - Recommended first-line diagnostic test
Used in NHS and specialist care. - Ideal for post-treatment confirmation
Confirms eradication success. - Non-invasive testing method
No blood draw required. - High sensitivity and specificity
Reliable diagnostic accuracy. - Clinically validated approach
Evidence-based gastrointestinal testing. - Suitable for adults and children
Used across age groups. - Guides appropriate antibiotic therapy
Prevents unnecessary treatment.
Step by step – how the test works
You can access H. pylori stool antigen testing UK-wide through two options:
- Clinic appointment
Collect your stool sample using the provided kit and return it to your nearest clinic. - At-home testing
Collect your stool sample at home following clear instructions and return it securely.
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Your results explained
Negative H. pylori antigen
No active H. pylori infection detected.
Typical UK interpretation:
- H. pylori antigen: Not detected
Positive H. pylori antigen
Active H. pylori infection detected. Treatment is usually recommended.
Typical UK interpretation:
- H. pylori antigen: Detected
Post-treatment testing
Testing is usually performed at least 4 weeks after antibiotics to confirm eradication.
Results should always be interpreted in clinical context.
How It Works
Simple steps to get your results
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Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.