Harmony® Prenatal Test (Non-Invasive Prenatal Testing)
Private Harmony® NIPT in London for £738.99, using maternal blood to screen for common chromosomal conditions from around 10 weeks.
Turnaround time
5 business days
Biomarkers count
1
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Overview of the Harmony® Prenatal Test (Non-Invasive Prenatal Testing)
The Harmony® Prenatal Test is a Non-Invasive Prenatal Test, or NIPT, that analyses cell-free DNA circulating in the pregnant person's blood to estimate the chance of selected chromosomal conditions.
The test contains 1 specialist screening component: Harmony® Prenatal Test (Non-Invasive Prenatal Testing) - common aneuploidy screening from maternal blood.
During pregnancy, fragments of cell-free DNA from the placenta circulate within maternal blood.
NIPT analyses this DNA to assess whether there is evidence suggesting an increased or reduced chance of certain chromosome-number abnormalities.
The principal conditions screened by the Harmony® test are Trisomy 21, Trisomy 18 and Trisomy 13.
Trisomy 21 causes Down's syndrome.
Trisomy 18 causes Edwards' syndrome.
Trisomy 13 causes Patau's syndrome.
The Harmony® Prenatal Test can generally be performed from approximately 10 weeks of pregnancy.
Because it requires only a maternal blood sample, it does not carry the procedure-related pregnancy risks associated with invasive diagnostic tests such as Chorionic Villus Sampling or amniocentesis.
However, NIPT is a screening test rather than a diagnostic test.
A lower-chance result substantially reduces the likelihood of the screened conditions but does not guarantee that the pregnancy is unaffected by every chromosomal, genetic or structural condition.
A higher-chance result also does not prove that the fetus has the condition.
Diagnostic confirmation through CVS or amniocentesis should be discussed before irreversible pregnancy decisions are made.
Occasionally, the laboratory may be unable to produce a result because there is insufficient placental cell-free DNA or another technical or biological factor interferes with analysis.
Routine antenatal ultrasound and maternity care remain important even after a lower-chance NIPT result.
What Does the Harmony® Prenatal Test (Non-Invasive Prenatal Testing) Check?
The Harmony® test analyses placental cell-free DNA circulating in maternal blood to provide a screening assessment for common fetal aneuploidies. This test contains 1 specialist screening component.
Harmony® Prenatal Test (Non-Invasive Prenatal Testing) - common aneuploidy screening from maternal blood
Uses cell-free DNA in maternal blood to estimate the chance of common chromosomal conditions including Trisomy 21, Trisomy 18 and Trisomy 13.
Who May Benefit From the Harmony® Prenatal Test (Non-Invasive Prenatal Testing)?
NIPT may be considered by pregnant individuals who want more accurate non-invasive screening information for common trisomies.
Pregnant individuals seeking non-invasive prenatal screening - Harmony® uses a maternal blood sample rather than an invasive procedure.
People who want screening from around 10 weeks of pregnancy - Cell-free DNA analysis can generally be performed early in pregnancy.
People with a higher-chance combined or first-trimester screening result - NIPT may provide additional screening information before deciding whether to undergo diagnostic testing.
Pregnant individuals aged 35 or over - Maternal age can increase the background chance of some chromosomal conditions, although NIPT is not restricted to this age group.
People with a previous pregnancy affected by a common trisomy - Specialist counselling can determine the most appropriate screening or diagnostic pathway.
People who prefer to avoid an invasive diagnostic test unless clearly indicated - NIPT can refine risk before considering CVS or amniocentesis.
People seeking additional screening information alongside routine antenatal care - NIPT can complement, but does not replace, ultrasound and maternity assessment.
How to Prepare
NIPT should be considered alongside appropriate antenatal counselling and ultrasound assessment.
Eligibility and interpretation can be affected by multiple pregnancy, vanished twin, transplantation, maternal chromosomal conditions and other biological factors.
Symptoms and Reasons to Consider the Harmony® Prenatal Test (Non-Invasive Prenatal Testing)
NIPT is not a symptom-driven test. It is performed to estimate the chance of selected chromosomal conditions during pregnancy.
A desire for early prenatal screening information - Harmony® can generally be performed from around 10 weeks.
A higher-chance result from conventional screening - NIPT can provide a more accurate second-stage screening assessment.
A maternal-age-related increase in chromosomal risk - Age can influence the background prevalence of common trisomies.
A previous pregnancy affected by a chromosomal condition - Genetic counselling can help determine whether screening or direct diagnostic testing is most appropriate.
An ultrasound finding requiring further risk assessment - NIPT may contribute in some circumstances, although significant structural abnormalities can warrant direct fetal-medicine assessment.
A preference for non-invasive screening before considering diagnostic procedures - The test requires only maternal venous blood.
Harmony® is not a diagnostic test.
Where ultrasound findings strongly suggest a chromosomal or structural abnormality, or where a definitive answer is needed, specialist fetal-medicine assessment and diagnostic testing may be more appropriate than relying solely on NIPT.
How to Book Your Harmony® Prenatal Test (Non-Invasive Prenatal Testing)
The Harmony® Prenatal Test can be booked privately from the appropriate stage of pregnancy following review of the relevant pregnancy information.
Choose the Harmony® Prenatal Test (Non-Invasive Prenatal Testing)
Select the Harmony® NIPT screening test online.
Select your sample collection option
Choose an in-clinic blood draw or a suitable professional home or hotel collection appointment.
Attend your appointment
A trained healthcare professional collects the required maternal venous blood sample and records the relevant pregnancy details.
Laboratory analysis
Cell-free DNA from the maternal blood sample undergoes specialist prenatal screening analysis.
Receive your results securely
Your authorised screening result is delivered securely, with specialist follow-up advised for higher-chance or inconclusive findings.
When Will I Receive My Results?
The current expected turnaround for the Harmony® Prenatal Test is approximately 5 days after the sample reaches the specialist laboratory.
The test requires extraction and analysis of cell-free DNA together with specialist quality-control procedures.
Turnaround begins from laboratory receipt rather than necessarily from the exact time your blood is collected.
A result may occasionally be delayed if the laboratory needs additional quality review.
In some pregnancies, the amount of analysable placental DNA is insufficient to produce a reliable result.
This may lead to a no-result or inconclusive report and can require repeat blood collection or discussion of alternative screening or diagnostic options.
Understanding Your Results
Harmony® results are screening results and are commonly reported as a lower or higher chance for the conditions assessed.
A lower-chance result means the screened trisomy is substantially less likely.
It does not reduce the chance to zero and cannot exclude every chromosome, genetic or structural condition.
A higher-chance result means the laboratory has identified a pattern associated with an increased likelihood of the specified chromosomal condition.
It is not a definitive diagnosis.
The positive predictive value of any screening result depends partly on the background chance of the condition, which can be influenced by maternal age and other factors.
A higher-chance result should therefore be discussed with an appropriate maternity or fetal-medicine team.
CVS or amniocentesis can provide diagnostic chromosome information where confirmation is required.
An inconclusive or no-result test does not mean that a chromosomal condition is present, but further assessment should be discussed.
Why Book With London Blood Tests?
London Blood Tests provides private access to specialist NIPT using a straightforward maternal blood sample.
Non-invasive prenatal screening - Requires only maternal venous blood.
Screens common trisomies - Provides risk assessment for Trisomy 21, Trisomy 18 and Trisomy 13.
Available from around 10 weeks - Allows early pregnancy screening information.
No procedure-related fetal risk from the blood draw - Unlike CVS or amniocentesis, blood collection itself is non-invasive to the pregnancy.
Clear screening interpretation - Results are reported as risk information rather than being presented as a definitive diagnosis.
Specialist laboratory analysis - Cell-free DNA undergoes dedicated prenatal screening analysis.
Professional collection options - Clinic and suitable home appointments are available.
Clear pricing - The Harmony® Prenatal Test costs £738.99.
Private Harmony® Prenatal Test (Non-Invasive Prenatal Testing) in London
London Blood Tests provides private Harmony® NIPT for pregnant individuals seeking screening for common chromosomal conditions.
The test costs £738.99 and contains 1 specialist NIPT screening component.
Testing can generally be performed from approximately 10 weeks of pregnancy.
Results are expected approximately 5 days after laboratory receipt.
Harmony® is a screening test and does not replace diagnostic testing, ultrasound examination or routine antenatal care.