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Herpes Simplex I/II by PCR (Urine)

Viral & Bacterias Screen
185.99

Private HSV I/II PCR urine testing in London for £185.99, detecting viral genetic material with results expected in around 5 days.

Turnaround time

5 business days

Biomarkers count

1

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Overview of the Herpes Simplex I/II by PCR (Urine) Test

The Herpes Simplex I/II by PCR (Urine) test uses Polymerase Chain Reaction technology to look for Herpes Simplex Virus genetic material within a urine specimen.

The test contains 1 grouped biomarker: Herpes Simplex I/II by PCR (Urine).

PCR detects viral DNA rather than antibodies.

This means it is designed to identify evidence of current viral shedding in the submitted sample rather than showing whether the person has ever previously been infected.

HSV-1 and HSV-2 can both cause genital infection.

HSV-1 is traditionally associated with oral herpes but is also an increasingly important cause of genital herpes.

HSV-2 predominantly causes genital infection and establishes lifelong latent infection after acquisition.

Urine PCR can provide evidence of active HSV DNA shedding within the sampled genitourinary tract.

However, the specimen type matters.

Where a person has a fresh visible genital ulcer, blister or vesicle, PCR from the lesion itself is generally preferred, because sampling directly from an active lesion provides the best opportunity to detect the virus causing that lesion.

HSV shedding is intermittent.

A negative urine PCR therefore does not prove that a person has never been infected with HSV.

It may simply mean that detectable viral DNA was not present in that particular specimen at that particular time.

Where there are no active lesions and the question is whether established HSV infection is present, IgG serology may provide different information.

The test should therefore be selected according to whether the aim is to identify active viral shedding or established previous infection.

What Does the Herpes Simplex I/II by PCR (Urine) Test Check?

This molecular test examines a urine specimen for HSV genetic material associated with active viral shedding. This test measures 1 grouped biomarker.

Herpes Simplex Virus PCR
Herpes Simplex I/II by PCR (Urine)

Detects HSV-1 and/or HSV-2 genetic material in urine using PCR to support assessment of active viral shedding or infection.

Who May Benefit From the Herpes Simplex I/II by PCR (Urine) Test?

Urine PCR may be useful where genitourinary HSV infection is being considered and urine is the selected specimen type.

People undergoing molecular STI assessment where HSV urine PCR has been specifically requested - The test can provide direct viral detection rather than antibody information.

People with genital symptoms but no suitable lesion available for swabbing - Urine PCR may provide supplementary molecular information, although sensitivity depends on viral shedding.

People with a previous positive HSV result requiring further investigation - PCR can address active shedding rather than previous antibody exposure.

People who want a molecular rather than antibody-based test - PCR detects viral DNA rather than the immune response.

People being assessed as part of a broader PCR sexual-health pathway - HSV may be tested alongside other organisms according to the clinical situation.

How to Prepare

Fasting
Fasting is not required.
Hydration
Maintain normal hydration and avoid deliberately over-diluting the urine specimen.
Urine collection
Follow the laboratory's exact urine collection instructions and use the supplied container.
Medication
Continue prescribed medication unless advised otherwise.
Antiviral treatment
Tell the clinician about Aciclovir, Valaciclovir or other antiviral treatment.
Symptoms
Record whether active genital symptoms or lesions are currently present.
Active lesions
If a fresh blister or ulcer is present, tell the clinician because direct lesion PCR may be preferable.
Previous tests
Keep previous HSV PCR or antibody results for comparison.

Do not deliberately overhydrate immediately before providing the sample.

The quality and timing of the submitted specimen are important because PCR can only detect viral DNA that is present in the sample.

Symptoms and Reasons to Consider the Herpes Simplex I/II by PCR (Urine) Test

HSV can cause a range of genital symptoms, although active lesions should generally be sampled directly where possible.

Painful genital blisters - HSV is an important cause of painful vesicular genital lesions.

Genital ulcers - PCR from a fresh lesion is generally preferred where an ulcer can be swabbed.

Burning or tingling in the genital area - Prodromal symptoms can occur before lesions appear.

Pain during urination with genital irritation - HSV lesions around the urethral area can make urination painful.

Recurrent episodes of genital soreness - Reactivation can cause repeated symptoms.

Genital symptoms following a new sexual exposure - Appropriate STI assessment may include HSV alongside other infections.

A partner with known genital herpes - Testing options depend on whether active symptoms are present.

A negative urine PCR does not exclude HSV infection because viral shedding is intermittent.

Fresh genital lesions should ideally be assessed promptly because lesion PCR is more diagnostically useful than random testing when a visible lesion is available.

How to Book Your Herpes Simplex I/II by PCR (Urine) Test

The HSV urine PCR test can be booked privately when a urine-based molecular assessment has been selected.

1
Choose the Herpes Simplex I/II by PCR (Urine)

Select the individual HSV urine PCR test online.

2
Select your sample collection option

Obtain the appropriate urine collection pathway and specimen container.

3
Attend your appointment

Provide the requested urine sample according to the laboratory instructions.

4
Laboratory analysis

The specimen undergoes PCR analysis for Herpes Simplex Virus genetic material.

5
Receive your results securely

Your authorised molecular result is delivered securely and can be interpreted alongside symptoms and any additional STI investigations.

When Will I Receive My Results?

The expected laboratory turnaround for Herpes Simplex I/II by PCR (Urine) is approximately 5 days after the specimen reaches the laboratory.

PCR requires extraction and amplification of viral genetic material together with laboratory quality-control procedures.

The turnaround starts from laboratory receipt rather than from the time the urine specimen is produced.

An unsuitable specimen or technical repeat analysis can delay reporting.

If a fresh genital lesion is present, direct lesion PCR should not be delayed simply to wait for a urine PCR result.

Understanding Your Results

A negative result means HSV genetic material was not detected in the submitted urine specimen.

This indicates no detectable viral shedding in that sample but does not exclude established HSV infection.

HSV can remain latent and shed intermittently.

A positive result means HSV genetic material was detected and supports active viral shedding or infection at the time represented by the specimen.

The result should be interpreted with symptoms and exposure history.

If infection type, site or longer-term status remains uncertain, additional lesion testing or type-specific IgG assessment may be appropriate.

Why Book With London Blood Tests?

London Blood Tests provides private urine-based HSV molecular testing for people requiring direct viral detection.

PCR technology - Detects HSV genetic material rather than relying on antibody production.

Urine-based sample - Provides a non-blood molecular testing option.

Relevant to active infection assessment - A positive result supports active viral shedding.

Can complement lesion or antibody testing - Different HSV tests answer different diagnostic questions.

Confidential sexual-health testing - Results are handled privately.

Specialist laboratory analysis - Samples undergo molecular virology testing.

Secure reporting - Receive your authorised result confidentially.

Clear pricing - The Herpes Simplex I/II by PCR (Urine) test costs £185.99.

Private Herpes Simplex I/II by PCR (Urine) Test in London

London Blood Tests provides private Herpes Simplex I/II PCR urine testing for people requiring molecular assessment of HSV.

The test costs £185.99 and contains 1 grouped biomarker.

Results are expected approximately 5 days after laboratory receipt.

A negative urine result does not exclude latent HSV infection, particularly when no viral shedding was occurring at the time of collection.

Frequently Asked Questions

It detects Herpes Simplex Virus genetic material in the submitted urine specimen.

No. PCR detects viral DNA directly.

Yes. Both HSV-1 and HSV-2 can cause genital infection.

Usually not. A direct PCR swab from a fresh active lesion is generally preferred.

No. HSV shedding is intermittent.

Yes. Detection of viral DNA supports active viral shedding in the sampled site.

No.

Antiviral treatment can reduce viral replication and should be documented.

No. IgG identifies an established antibody response, while PCR looks for viral genetic material.

Results are expected approximately 5 days after laboratory receipt.
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