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HRT Baseline Screening Profile
Recommended
199.00
This panel provides a complete baseline assessment before starting hormone replacement therapy (HRT). It evaluates hormone balance, metabolic health, organ function and key safety markers to guide treatment decisions.
Turnaround time
Biomarkers count
48
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about HRT Baseline Screening Profile
What is the HRT Baseline Screening Profile?
The HRT Baseline Screening Profile is a comprehensive pre-treatment blood panel designed to evaluate whether your body is prepared for hormone replacement therapy safely and effectively. It measures reproductive hormones alongside thyroid function, metabolic markers, cardiovascular risk, and nutrient status — all factors that influence hormone response and treatment outcomes.
Establishing a baseline before starting HRT allows clinicians to personalise therapy, optimise dosing, and reduce the risk of unwanted side effects or complications.
What does the profile include?
Core Hormones
Oestradiol (E2)
Progesterone
Testosterone (Total and Free)
Sex Hormone Binding Globulin (SHBG)
Free Androgen Index (calculated)
Luteinising Hormone (LH)
Follicle Stimulating Hormone (FSH)
Prolactin
These markers assess reproductive hormone balance, menopausal status, and androgen activity.
Thyroid Function (essential before HRT)
Thyroid Stimulating Hormone (TSH)
Free Thyroxine (Free T4)
Free Tri-iodothyronine (Free T3)
Thyroid health strongly influences metabolism, energy, and hormone responsiveness.
Metabolic & Safety Markers
Fasting Glucose
HbA1c
Lipid Profile (Total Cholesterol, HDL, LDL, Triglycerides)
These markers assess metabolic health and cardiovascular risk prior to hormone therapy.
Liver & Kidney Function
Alanine Aminotransferase (ALT)
Aspartate Aminotransferase (AST)
Alkaline Phosphatase (ALP)
Gamma-Glutamyltransferase (GGT)
Bilirubin
Albumin
Creatinine
eGFR
Urea
Organ function testing ensures hormones can be metabolised safely.
Cardiovascular & Inflammation
High-Sensitivity C-Reactive Protein (hs-CRP)
Full Blood Count (FBC)
These markers evaluate inflammation and overall cardiovascular health risk.
Nutritional Status (important for hormone response)
Vitamin D
Vitamin B12
Folate
Ferritin
Iron Studies
Nutrient status significantly influences hormone metabolism, energy levels, and treatment response.
Why do I need an HRT baseline test?
Hormone therapy interacts with multiple body systems, not just reproductive hormones. Without proper screening, underlying metabolic or thyroid issues may be missed, leading to poor symptom improvement or increased risk.
This test is recommended if you:
• Are considering HRT or hormone optimisation
• Have menopausal or perimenopausal symptoms
• Experience fatigue, weight gain, or mood changes
• Want a safe personalised hormone plan
• Are starting testosterone therapy
• Want objective baseline data before treatment
Benefits of the test
1. Establishes a safe starting point before HRT
2. Identifies hormonal imbalances accurately
3. Detects metabolic or thyroid issues early
4. Assesses cardiovascular risk before treatment
5. Supports personalised hormone dosing
6. Improves treatment outcomes and safety
7. Identifies nutrient deficiencies affecting response
8. Provides baseline for future monitoring
Expanded benefit explanation
By assessing hormones alongside safety markers, this panel ensures HRT is initiated with the highest level of clinical insight and safety.
Step-by-step — How testing works
We offer two UK-wide options:
Clinic testing
• Choose your nearest UK clinic
• Blood sample collected by clinician
• Samples analysed by accredited laboratory
• Results delivered securely
Home visit (+£60)
• Phlebotomist visits your home or hotel
• Blood collected safely and professionally
• Samples sent to laboratory
• Results delivered securely
Both services are available UK-wide.
Your results explained
Low hormone levels
May indicate menopause, androgen deficiency, or hormonal suppression.
Balanced ranges
Suggest hormonal stability and readiness for therapy.
Elevated markers
May indicate inflammation, metabolic risk, or endocrine imbalance requiring optimisation before HRT.
Reference ranges are provided with all results for clinical interpretation.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
Yes, baseline testing is strongly recommended for safety.
Yes, fasting improves metabolic marker accuracy.
Yes, depending on therapy type.
Yes, hormone patterns can indicate menopausal status.
Thyroid function affects hormone response significantly.
It can, which is why lipids are checked.
Yes, especially vitamin D and iron.
Typically 3–6 months after starting therapy.
Yes, results help personalise therapy.
Yes, as a preventative baseline.
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