Immunoglobulins (IgG, IgM, IgA)
Private Immunoglobulins IgG, IgM and IgA test in London for £99, providing a three-marker overview of antibody-mediated immune function.
Turnaround time
1 week
Biomarkers count
3
Book your test
Choose Service Type
Professional phlebotomist comes to you
+ £{{ home_visit_fee }}
Visit our clinic for your test
{{ clinic_visit_fee > 0 ? '+ £' + clinic_visit_fee : 'Free' }}
Home Visit Details
Home visits require at least 24 hours notice.
Select a clinic: Sorting by distance…
{{ clinicAddress(clinic) }}
{{ clinicAddress(selectedClinic) }}
Select a date
Select an hour
Available time slots: {{ timeSlots.length}}
Overview of the Immunoglobulins (IgG, IgM, IgA) Test
The Immunoglobulins (IgG, IgM, IgA) test measures the three major antibody classes Immunoglobulin G, Immunoglobulin M and Immunoglobulin A.
The test contains 3 biomarkers: Immunoglobulin A, Immunoglobulin G and Immunoglobulin M.
Immunoglobulins are proteins produced by B lymphocytes and plasma cells and form a central part of the body's humoral immune response.
Each antibody class has different biological roles.
IgG is the most abundant immunoglobulin in blood and provides much of the body's longer-term antibody-mediated defence against infection.
IgM is typically the first major immunoglobulin class produced during an initial immune response and is also important in the body's natural antibody repertoire.
IgA is particularly important at mucosal surfaces such as the respiratory and gastrointestinal tracts, although this blood test measures circulating serum IgA.
Measuring all three classes together can provide a useful first-line assessment when antibody deficiency or abnormal immunoglobulin production is suspected.
Low concentrations may occur with primary or secondary immunodeficiency.
Higher concentrations can be associated with chronic infection, inflammatory disease, liver conditions, autoimmune activity or monoclonal and polyclonal immunoglobulin disorders.
The pattern matters more than one isolated number.
For example, a selective reduction in IgA has different implications from a reduction affecting IgG, IgM and IgA together.
If the results are abnormal, further testing may include IgG Subclasses, Serum Protein Electrophoresis, immunofixation, vaccine-antibody responses or specialist immunology investigations depending on the pattern.
What Does the Immunoglobulins (IgG, IgM, IgA) Test Check?
The profile provides a broad quantitative assessment of three major circulating antibody classes involved in infection defence and immune regulation. This test measures 3 biomarkers.
Immunoglobulin A
Measures serum IgA, an antibody class strongly associated with mucosal immune defence.
Immunoglobulin G
Measures total IgG, the principal immunoglobulin involved in sustained systemic antibody-mediated immunity.
Immunoglobulin M
Measures total IgM, an antibody class involved prominently in early immune responses and primary antibody production.
Who May Benefit From the Immunoglobulins (IgG, IgM, IgA) Test?
The profile may be particularly useful when recurrent infections, suspected immune deficiency or unexplained changes in blood proteins require a broad initial assessment.
People with recurrent sinus or chest infections - Low antibody levels can impair defence against respiratory pathogens.
People with repeated bacterial infections requiring antibiotics - Quantitative immunoglobulin testing may form part of immune-deficiency assessment.
People with unusual or severe infections - Broader immune evaluation may be appropriate.
People with chronic gastrointestinal infections or symptoms and suspected immune deficiency - IgA and other immunoglobulins may be relevant.
People being investigated by an immunologist - IgG, IgM and IgA are common baseline immunology measurements.
People with a previous low immunoglobulin result - Repeat testing can determine whether the abnormality persists.
People with autoimmune or chronic inflammatory conditions - Immunoglobulins can be increased as part of broader immune activation.
People with abnormal Total Protein or Globulin results - Quantitative immunoglobulin measurement can help clarify whether antibodies contribute to the change.
People taking medicines that can suppress antibody production - Monitoring may be appropriate depending on treatment.
How to Prepare
Do not stop prescribed immunosuppressive or immunoglobulin-replacement treatment simply to alter the result.
If the test is being performed immediately before an immunoglobulin infusion, follow the timing instructions provided by the specialist team.
Symptoms and Reasons to Consider the Immunoglobulins (IgG, IgM, IgA) Test
Abnormal immunoglobulin concentrations do not produce a single specific symptom pattern. Testing is commonly prompted by recurrent infection or other evidence of altered immune function.
Repeated sinus infections - Antibody deficiency can contribute to recurrent upper respiratory bacterial infections.
Frequent chest infections or pneumonia - Low IgG or other humoral immune abnormalities may increase susceptibility.
Repeated ear infections - Recurrent bacterial infection can prompt quantitative immunoglobulin assessment.
Prolonged recovery from infections - Inadequate antibody responses may contribute in selected individuals.
Chronic gastrointestinal infections - Some antibody deficiencies can affect mucosal infection defence.
Unexplained recurrent illness - Broader immune assessment may be appropriate when infections are unusually frequent or severe.
A previous low IgG, IgM or IgA result - Repeat testing can establish whether the change is persistent.
Unexplained raised Globulin or Total Protein - Increased immunoglobulin production is one possible explanation.
Frequent infections do not automatically mean that an immunoglobulin deficiency is present.
Serious or recurrent infections may require assessment of lymphocyte numbers, vaccine responses, complement function and other aspects of the immune system even when IgG, IgM and IgA are within their reference intervals.
How to Book Your Immunoglobulins (IgG, IgM, IgA) Test
The Immunoglobulins profile can be booked privately for quantitative assessment of the three major circulating antibody classes.
Choose the Immunoglobulins (IgG, IgM, IgA)
Select the three-marker immunoglobulin profile online.
Select your sample collection option
Choose an in-clinic blood draw or professional home or hotel phlebotomy.
Attend your appointment
A trained healthcare professional collects the required venous blood sample.
Laboratory analysis
Your serum is analysed for quantitative Immunoglobulin A, Immunoglobulin G and Immunoglobulin M.
Receive your results securely
Your authorised immune profile is delivered securely and can be reviewed with a GP or immunology specialist where appropriate.
When Will I Receive My Results?
The current London Blood Tests turnaround for the Immunoglobulins (IgG, IgM, IgA) profile is approximately 7 days after laboratory receipt.
The three immunoglobulin classes undergo quantitative laboratory measurement and quality-control review before the profile is authorised.
Turnaround begins when the sample reaches the laboratory rather than necessarily from the time your blood is collected.
Although individual immunoglobulin assays can be available more quickly in some laboratory pathways, the current listed turnaround for this combined profile should be treated as approximately seven days.
Additional specialist testing requested after an abnormal result will have its own turnaround.
Understanding Your Results
The three immunoglobulins should be interpreted together because the pattern can provide more information than one value alone.
Low IgG may indicate impaired systemic antibody production and can be associated with increased susceptibility to bacterial respiratory infections.
Low IgA may occur in selective IgA deficiency, although many people with reduced IgA remain relatively well.
Low IgM can occur in selected primary or secondary immune disorders.
Reduction in several classes together may suggest a broader humoral immunodeficiency and can require specialist investigation.
Raised immunoglobulin concentrations may be polyclonal, where several antibody populations are increased during infection, inflammation or liver disease.
More focused or disproportionate elevations may prompt Serum Protein Electrophoresis or other investigations for monoclonal immunoglobulin production.
Age, clinical history, treatment and the laboratory's own reference intervals must all be considered.
Why Book With London Blood Tests?
London Blood Tests provides a convenient private three-marker assessment of major antibody classes within one profile.
Three major immunoglobulins measured together - IgG, IgM and IgA provide a broad overview of humoral immune function.
Useful for recurrent infection assessment - Low antibody concentrations can contribute to repeated bacterial infections.
Relevant to suspected immune deficiency - The profile is a common first-line quantitative immunology investigation.
Can identify patterns of immune activation - Raised immunoglobulins can provide information about chronic inflammatory or immune processes.
Can guide additional testing - Abnormal results may lead to IgG Subclasses, protein electrophoresis or functional antibody studies.
Private blood testing in London - Professional clinic and home or hotel phlebotomy can be arranged.
Secure reporting - Receive the authorised three-marker profile confidentially.
Clear pricing - The Immunoglobulins (IgG, IgM, IgA) test costs £99.
Private Immunoglobulins (IgG, IgM, IgA) Blood Test in London
London Blood Tests provides private quantitative Immunoglobulin testing in London for people requiring assessment of antibody levels and immune function.
The profile costs £99 and measures 3 biomarkers: Immunoglobulin A, Immunoglobulin G and Immunoglobulin M.
Results are expected approximately 7 days after laboratory receipt.
Abnormal concentrations should be interpreted according to the overall immunoglobulin pattern, infection history and other relevant immune investigations.