Immunoglobulins (IgG, IgM, IgA)
The Immunoglobulins test measures IgG, IgM and IgA antibody levels in the blood. It provides a broad assessment of immune system function.
Turnaround time
7 days
Biomarkers count
3
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Details about Immunoglobulins (IgG, IgM, IgA)
What is the Immunoglobulins (IgG, IgM, IgA) test?
The Immunoglobulins test measures the three main antibody classes in the blood: IgG, IgM and IgA. Together, these antibodies represent the core of the body’s humoral immune response.
Each immunoglobulin has a distinct role. IgG reflects long-term immunity and past exposure, IgM indicates early or recent immune activity, and IgA protects mucosal surfaces such as the gut and respiratory tract.
Testing all three provides a comprehensive overview of immune health, helping clinicians assess immune competence, infection history and immune regulation.
Why do I need an Immunoglobulins test?
Abnormal immunoglobulin levels may indicate immune deficiency, chronic infection, autoimmune disease or immune overactivity. Testing helps clarify whether symptoms are immune-related.
You may need an Immunoglobulins test if you:
- Have recurrent or severe infections
- Experience frequent respiratory or gut infections
- Have suspected immune deficiency
- Have autoimmune or inflammatory conditions
- Have unexplained fatigue or prolonged illness
- Are being assessed by an immunologist
- Need baseline immune function assessment
Conditions commonly investigated with this test include:
- Primary or secondary immunodeficiency
- Chronic or recurrent infections
- Autoimmune disease
- Chronic inflammation
- Certain liver or blood disorders
Benefits of the Immunoglobulins test
- Provides a complete immune overview
Measures the three main antibody classes. - Identifies immune deficiencies
Detects low antibody levels affecting infection defence. - Supports investigation of recurrent infections
Explains poor immune response. - Clinically established immune assessment
Used in NHS and specialist care. - Useful in autoimmune investigations
Elevated levels may reflect immune activation. - Guides further specialist testing
Helps determine need for subclass or functional tests. - Suitable for adults and children
Applied across age groups. - Simple blood test
Requires only one blood sample.
Step by step – how the test works
You can access Immunoglobulin testing UK-wide through two options:
- Clinic appointment
Choose your nearest UK clinic, where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Your results explained
Low immunoglobulin levels
May indicate immune deficiency and increased infection risk.
Typical UK reference ranges:
- IgG: < 7.0 g/L
- IgM: < 0.4 g/L
- IgA: < 0.7 g/L
Normal immunoglobulin levels
Suggest intact immune defence and antibody production.
Typical UK reference ranges:
- IgG: 7.0–16.0 g/L
- IgM: 0.4–2.3 g/L
- IgA: 0.7–4.0 g/L
High immunoglobulin levels
May reflect chronic infection, inflammation or autoimmune disease.
Typical UK interpretation:
- One or more immunoglobulins above reference range
Reference ranges may vary slightly between laboratories.
How It Works
Simple steps to get your results
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Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.