Lamotrigine
The Lamotrigine test measures the level of lamotrigine in the blood. It supports safe and effective treatment monitoring in epilepsy and mood disorders.
Turnaround time
8 days
Biomarkers count
1
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Details about Lamotrigine
What is the Lamotrigine test?
The Lamotrigine blood test measures the concentration of lamotrigine, an anticonvulsant and mood-stabilising medication, in the bloodstream. Lamotrigine is commonly prescribed for epilepsy and bipolar disorder, and occasionally for other neurological or psychiatric conditions.
Although lamotrigine has a wider therapeutic range than some other medications, blood level monitoring can be helpful in ensuring the dose is effective, safe, and consistent, particularly when symptoms are not well controlled or side effects occur.
This test is part of therapeutic drug monitoring (TDM) and helps personalise treatment based on how an individual metabolises the medication.
Why do I need a Lamotrigine test?
Lamotrigine levels can vary between individuals due to metabolism, interactions with other medications, or adherence issues. Monitoring helps optimise treatment and reduce risk.
You may need a Lamotrigine test if you:
- Are being treated for epilepsy
- Are taking lamotrigine for bipolar disorder
- Have ongoing seizures or mood instability
- Have recently changed dose
- Are starting or stopping interacting medications
- Experience side effects
- Need to check medication adherence
Symptoms linked to abnormal lamotrigine levels may include:
- Persistent seizures
- Mood instability
- Dizziness
- Headache
- Nausea
- Blurred vision
- Coordination problems
Benefits of the Lamotrigine test
- Supports optimal dosing
Helps ensure therapeutic effectiveness. - Reduces side-effect risk
Identifies excessive drug levels. - Useful in treatment-resistant cases
Clarifies whether dose is adequate. - Supports epilepsy management
Helps maintain seizure control. - Useful in bipolar disorder treatment
Supports mood stabilisation. - Clinically recognised monitoring test
Used in neurology and psychiatry. - Helps assess drug interactions
Important when medications change. - Simple blood test
Requires only one sample.
Step by step – how the test works
You can access Lamotrigine testing UK-wide through two options:
- Clinic appointment
Attend your nearest UK clinic, where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, maintaining correct sample timing.
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Your results explained
Low lamotrigine level
May indicate under-dosing, poor absorption or non-adherence.
Typical UK interpretation:
- < 3 mg/L
Therapeutic lamotrigine level
Suggests effective and safe medication concentration.
Typical UK interpretation:
- 3–14 mg/L
High lamotrigine level
May increase risk of side effects or toxicity.
Typical UK interpretation:
- > 14 mg/L
Therapeutic ranges may vary slightly depending on clinical context.
How It Works
Simple steps to get your results
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.