LDL7 Subfractions
The LDL7 Subfractions test analyses different LDL particle types in the blood. It provides deeper insight into cardiovascular risk beyond standard LDL cholesterol.
Turnaround time
10 days
Biomarkers count
7
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Details about LDL7 Subfractions
What is the LDL7 Subfractions test?
The LDL7 Subfractions test is an advanced lipid analysis that separates low-density lipoprotein (LDL) cholesterol into seven distinct particle subfractions based on size and density.
Not all LDL particles carry the same cardiovascular risk. Smaller, denser LDL particles are more atherogenic, meaning they penetrate arterial walls more easily and are more prone to oxidation, while larger, buoyant LDL particles are generally considered less harmful.
This test provides a more refined cardiovascular risk assessment than standard LDL-C measurements alone.
Why do I need an LDL7 Subfractions test?
Standard cholesterol tests may underestimate cardiovascular risk in some individuals. LDL subfraction testing helps uncover hidden risk, especially when LDL-C appears “normal”.
You may need an LDL7 Subfractions test if you:
- Have normal LDL but strong family history of heart disease
- Have metabolic syndrome or insulin resistance
- Have diabetes or prediabetes
- Have unexplained cardiovascular risk
- Have high triglycerides
- Are optimising cardiovascular prevention
- Want advanced lipid risk assessment
Conditions associated with small, dense LDL particles include:
- Insulin resistance
- Type 2 diabetes
- Obesity
- Metabolic syndrome
- Cardiovascular disease
Benefits of the LDL7 Subfractions test
- Advanced cardiovascular risk stratification
Goes beyond standard LDL-C testing. - Identifies atherogenic LDL particles
Detects small, dense LDL fractions. - Improves preventive decision-making
Supports targeted lifestyle or treatment plans. - Useful in metabolic health assessment
Links lipid patterns to insulin resistance. - Explains risk with normal cholesterol
Reveals hidden atherosclerotic risk. - Clinically relevant in high-risk patients
Used in advanced lipidology. - Supports personalised medicine
Tailors cardiovascular strategies. - Single blood test
Detailed insights from one sample.
Step by step – how the test works
You can access LDL7 Subfractions testing UK-wide through two options:
- Clinic appointment
Attend your nearest UK clinic where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.
Your sample is analysed in an accredited UK laboratory using advanced lipid fractionation techniques.
Your results explained
Low cardiovascular risk pattern
- Predominantly large, buoyant LDL particles
- Minimal small, dense LDL fractions
Typical UK interpretation:
- LDL Pattern A (larger LDL)
Intermediate risk pattern
- Mixed LDL particle sizes
Typical UK interpretation:
- Mixed LDL subfractions
High cardiovascular risk pattern
- High proportion of small, dense LDL particles
Typical UK interpretation:
- LDL Pattern B (small, dense LDL)
Results should be interpreted alongside ApoB, triglycerides and clinical risk factors.
How It Works
Simple steps to get your results
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.