The Leptin test measures a hormone involved in appetite and energy balance. It helps assess metabolic health and leptin resistance.
Turnaround time
2 weeks
Biomarkers count
1
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Visit our clinic for your test
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Home visits require at least 24 hours notice.
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The Leptin blood test measures the level of leptin, a hormone produced primarily by fat (adipose) tissue. Leptin plays a central role in regulating appetite, energy expenditure, and body weight by signalling satiety to the brain.
Under normal conditions, higher body fat leads to higher leptin levels, which should reduce appetite. However, in many individuals—particularly those with obesity—this signalling becomes impaired, a condition known as leptin resistance.
Leptin testing is used in metabolic health assessment, weight management evaluation, and investigation of unexplained appetite or weight regulation issues.
Abnormal leptin levels can indicate disrupted appetite signalling and metabolic dysfunction. Testing helps distinguish between hormonal drivers of weight gain and lifestyle factors.
You may need a Leptin test if you:
Conditions linked to abnormal leptin levels include:
You can access Leptin testing UK-wide through two options:
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Low leptin levels
May be seen in low body fat, starvation, or rare congenital leptin deficiency.
Typical UK interpretation:
Normal leptin levels
Suggest appropriate fat mass signalling and appetite regulation.
Typical UK interpretation:
High leptin levels
Often indicate leptin resistance, where appetite remains high despite elevated leptin.
Typical UK interpretation:
Leptin levels must be interpreted relative to body fat, sex and metabolic context.
Simple steps to get your results
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsFollow these guidelines for accurate results
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
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