Lipase
The Lipase test measures an enzyme produced by the pancreas. It is essential for diagnosing pancreatic inflammation and dysfunction.
Turnaround time
1 day
Biomarkers count
1
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Details about Lipase
What is the Lipase test?
The Lipase blood test measures the level of lipase, a digestive enzyme produced primarily by the pancreas. Lipase plays a critical role in breaking down dietary fats into smaller molecules that can be absorbed by the body.
When the pancreas becomes inflamed or damaged, lipase leaks into the bloodstream, causing levels to rise. Because lipase is more pancreas-specific and remains elevated longer than amylase, it is a key marker in pancreatic disease assessment.
This test is widely used in emergency, gastroenterology, and routine diagnostic settings to evaluate pancreatic health.
Why do I need a Lipase test?
Elevated or abnormal lipase levels can indicate pancreatic inflammation or injury, which may require urgent medical attention.
You may need a Lipase test if you:
- Have severe or persistent abdominal pain
- Experience nausea or vomiting
- Have suspected acute or chronic pancreatitis
- Have gallstones or heavy alcohol use history
- Have unexplained digestive symptoms
- Are being monitored for pancreatic disease
- Have abnormal imaging results involving the pancreas
Symptoms associated with abnormal lipase levels include:
- Upper abdominal pain radiating to the back
- Nausea and vomiting
- Fever
- Abdominal tenderness
- Loss of appetite
Benefits of the Lipase test
- Key marker for pancreatitis
Highly sensitive for pancreatic inflammation. - More specific than amylase
Better reflects pancreatic damage. - Supports rapid diagnosis
Essential in acute abdominal pain assessment. - Clinically established enzyme test
Used routinely in hospital and outpatient care. - Guides treatment decisions
Helps determine urgency and management. - Useful in monitoring recovery
Tracks resolution of pancreatic inflammation. - Supports differential diagnosis
Helps distinguish pancreatic from non-pancreatic causes. - Simple blood test
Requires only one blood sample.
Step by step – how the test works
You can access Lipase testing UK-wide through two options:
- Clinic appointment
Attend your nearest UK clinic, where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Your results explained
Low lipase levels
Usually not clinically significant but may be seen in chronic pancreatic insufficiency.
Typical UK interpretation:
- Below reference range
Normal lipase levels
Suggest normal pancreatic enzyme production.
Typical UK interpretation:
- Within reference range
High lipase levels
Strongly suggest pancreatic inflammation or injury, especially acute pancreatitis.
Typical UK interpretation:
- > 3× upper reference limit (often clinically significant)
Results must be interpreted alongside symptoms and other investigations.
How It Works
Simple steps to get your results
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.