Lipoprotein (a)
The Lipoprotein (a) test measures a genetically determined cholesterol particle. It helps identify hidden cardiovascular risk even when standard lipids are normal.
Turnaround time
2 days
Biomarkers count
1
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Details about Lipoprotein (a)
What is the Lipoprotein (a) test?
The Lipoprotein (a), often written as Lp(a), test measures a specific type of cholesterol particle made up of LDL cholesterol bound to a unique protein called apolipoprotein(a). Unlike other lipids, Lp(a) levels are largely genetically determined and remain relatively stable throughout life.
Lp(a) is considered atherogenic and pro-thrombotic, meaning it contributes to plaque formation in arteries and increases clotting risk. Standard cholesterol panels do not measure Lp(a), which is why cardiovascular risk may be underestimated without it.
This test is increasingly recommended in preventive cardiology and advanced cardiovascular risk assessment.
Why do I need a Lipoprotein (a) test?
Many people with normal cholesterol levels still develop cardiovascular disease. Elevated Lp(a) is a recognised independent risk factor.
You may need a Lipoprotein (a) test if you:
- Have a family history of early heart disease or stroke
- Have cardiovascular disease despite normal cholesterol
- Have high LDL that doesn’t respond well to treatment
- Have a history of aortic valve disease
- Want advanced cardiovascular risk screening
- Have recurrent clotting events
- Are assessing inherited lipid risk
Conditions linked to elevated Lipoprotein (a) include:
- Coronary artery disease
- Heart attack at a young age
- Stroke
- Peripheral artery disease
- Aortic valve stenosis
Benefits of the Lipoprotein (a) test
- Identifies inherited cardiovascular risk
Detects risk not seen on standard lipid panels. - One-time lifetime test for most people
Levels are genetically stable. - Improves heart disease risk stratification
Enhances prevention strategies. - Explains premature cardiovascular disease
Even with normal LDL levels. - Supports personalised lipid management
Guides intensity of risk reduction. - Clinically recognised risk marker
Endorsed by cardiology guidelines. - Relevant for family screening
Helps identify at-risk relatives. - Simple blood test
Requires only one sample.
Step by step – how the test works
You can access Lipoprotein (a) testing UK-wide through two options:
- Clinic appointment
Attend your nearest UK clinic, where a healthcare professional will take your blood sample. - At-home or hotel visit (£60 extra)
A qualified phlebotomist comes to your home or hotel, so you don’t need to travel.
Your sample is analysed in an accredited UK laboratory, and results are delivered securely.
Your results explained
Low Lipoprotein (a)
Associated with lower inherited cardiovascular risk.
Typical UK interpretation:
- < 30 mg/dL (or < 75 nmol/L)
Moderate Lipoprotein (a)
May contribute to cardiovascular risk, especially with other factors present.
Typical UK interpretation:
- 30–50 mg/dL (75–125 nmol/L)
High Lipoprotein (a)
Associated with significantly increased cardiovascular and clotting risk.
Typical UK interpretation:
- > 50 mg/dL (> 125 nmol/L)
Units and reference ranges may vary by laboratory.
How It Works
Simple steps to get your results
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Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.