What is the Longevity Core Metabolic & Cardiovascular Panel?

The Longevity Core Metabolic & Cardiovascular panel is a strategically designed blood test focused on the highest-return biomarkers for longevity, metabolic health, and cardiovascular risk. It targets insulin resistance, lipid-driven heart risk, inflammation, hormone balance, thyroid function, nutrient deficiencies, and organ clearance.

This panel is especially valuable for individuals who are overweight, vegetarian/plant-based, metabolically stressed, or proactively optimising long-term health.

Biomarkers included

Full Blood & Pancreatic Marker

• Full Blood Count (FBC)

• Lipase

Core Metabolic & Cardiovascular Health

• Fasting Glucose

• Fasting Insulin

• HbA1c

• HOMA-IR (calculated)

• Total Cholesterol

• Triglycerides

• HDL Cholesterol

• LDL Cholesterol

• High-Sensitivity C-Reactive Protein (hs-CRP)

Optional (high value):

• Apolipoprotein B (ApoB)

Liver & Kidney Function

(Commonly overlooked in overweight or vegetarian patients)

Liver

• Alanine Aminotransferase (ALT)

• Aspartate Aminotransferase (AST)

• Gamma-Glutamyl Transferase (GGT)

• Alkaline Phosphatase (ALP)

• Total Bilirubin

Kidney

• Creatinine

• Estimated Glomerular Filtration Rate (eGFR)

• Urea

Hormones (Male-focused, essential)

• Total Testosterone

• Free Testosterone (or calculated)

• Sex Hormone Binding Globulin (SHBG)

• Luteinising Hormone (LH)

• Follicle Stimulating Hormone (FSH)

• Estradiol (sensitive assay)

• Prolactin

• DHEA-S

• Cortisol (AM)

Thyroid

• Thyroid Stimulating Hormone (TSH)

• Free T4

• Free T3

Optional (high clinical value):

• Thyroid Peroxidase Antibodies (TPO)

• Thyroglobulin Antibodies (TgAb)

Nutrient Deficiencies

(Very high ROI in vegetarian or plant-based diets)

• Vitamin B12

• Folate

• Ferritin

• Serum Iron

• Transferrin / Total Iron-Binding Capacity (TIBC)

• Vitamin D (25-OH)

• Magnesium (serum minimum)

• Zinc

• Calcium

• Phosphate

Optional (balance marker):

• Copper

Why do I need a Longevity Core Metabolic & Cardiovascular Panel?

Longevity is driven less by rare genetics and more by metabolic control, inflammation, hormone balance, and nutrient sufficiency. This panel targets the most actionable systems linked to early ageing, cardiovascular disease, diabetes, and hormonal decline.

You may benefit from this panel if you:

• Want to assess insulin resistance early

• Are focused on cardiovascular disease prevention

• Follow a vegetarian or plant-based diet

• Have fatigue, weight gain, or poor body composition

• Want to optimise hormones safely

• Are planning lifestyle or peptide-based interventions

• Prefer a focused, high-ROI longevity panel

Benefits of the Longevity Core Metabolic & Cardiovascular Panel

1. Early insulin resistance detection
   Glucose, insulin, HbA1c, and HOMA-IR included.

2. Advanced cardiovascular risk insight
   Lipids, hs-CRP, and optional ApoB go beyond basics.

3. Inflammation & ageing insight
   hs-CRP highlights systemic risk.

4. Hormone optimisation foundation
   Androgens, adrenal, and pituitary markers included.

5. Thyroid-metabolism alignment
   Prevents missed metabolic drivers of fatigue and weight gain.

6. Vegetarian nutrient gap detection
   B12, iron, zinc, vitamin D commonly missed.

7. Liver & kidney clearance safety
   Supports long-term metabolic and supplement strategies.

8. High-ROI longevity screening
   Focused without unnecessary overtesting.

Step-by-step – how we offer Longevity Core testing

Clinic-based testing (UK-wide)

• Choose your nearest UK clinic

• Attend your appointment

• Blood samples collected by a qualified clinician

• Samples sent to the laboratory for analysis

At-home or hotel testing (+£60)

• A qualified phlebotomist visits your location

• Blood samples collected comfortably

• No clinic visit required

Both services are available UK-wide.

Your Longevity Core results explained

Sub-optimal or deficient markers

May indicate insulin resistance, hormonal suppression, nutrient depletion, inflammation, or impaired organ clearance affecting long-term health.

UK reference interpretation:

• Abnormal: Outside laboratory reference ranges

Optimal longevity ranges

Markers within range suggest good metabolic control, low inflammatory burden, and reduced long-term cardiovascular risk.

UK reference interpretation:

• Optimal: Within laboratory reference ranges

Elevated risk markers

Raised insulin, triglycerides, hs-CRP, GGT, or ApoB suggest higher cardiometabolic and ageing risk and benefit from early intervention.

UK reference interpretation:

• High risk: Above laboratory reference ranges