Lupus Anticoagulant
This test detects lupus anticoagulant, an antibody that interferes with normal blood clotting tests. It helps assess increased risk of thrombosis and pregnancy complications.
Turnaround time
5 days
Biomarkers count
1
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Details about Lupus Anticoagulant
What is the Lupus Anticoagulant Test?
The Lupus Anticoagulant test detects the presence of antiphospholipid antibodies that interfere with phospholipid-dependent clotting reactions in laboratory tests. Despite the name, lupus anticoagulant is associated with increased clotting risk, not bleeding.
These antibodies are part of a group linked to antiphospholipid syndrome (APS), an autoimmune condition that increases the risk of blood clots and pregnancy-related complications. The test is performed using specialised coagulation assays rather than a single measurement.
Lupus anticoagulant testing is typically interpreted alongside other antiphospholipid antibody tests and clinical history.
Why do I need a test for Lupus Anticoagulant?
You may need this test if you have experienced unexplained blood clots, recurrent miscarriages or abnormal clotting test results. Lupus anticoagulant can cause paradoxical laboratory findings while increasing real-world thrombotic risk.
Identifying these antibodies helps guide long-term anticoagulation decisions and pregnancy management, reducing the risk of future complications.
Symptoms and scenarios where testing is recommended:
- Unexplained deep vein thrombosis or pulmonary embolism
- Recurrent miscarriage or pregnancy loss
- Stroke or transient ischaemic attack at a young age
- Prolonged clotting test results without bleeding symptoms
- Suspected antiphospholipid syndrome
- Autoimmune disease assessment
- Monitoring known APS
- Unexplained arterial or venous thrombosis
Benefits of the Lupus Anticoagulant Test
- Identifies thrombotic risk factors
Detects antibodies linked to abnormal clotting. - Supports diagnosis of antiphospholipid syndrome
Key component of APS assessment. - Explains abnormal clotting test results
Clarifies paradoxical laboratory findings. - Guides anticoagulation decisions
Supports long-term clot prevention strategies. - Supports pregnancy risk assessment
Important in recurrent miscarriage evaluation. - Relevant in autoimmune disease workup
Often assessed alongside other autoantibodies. - Improves long-term risk management
Enables proactive monitoring and treatment. - Clinically established coagulation investigation
Widely used in haematology practice.
Step-by-Step: How Testing Works
Choose your preferred testing method
You can attend one of our UK partner clinics or arrange a home or hotel visit with a mobile phlebotomist.
Option 1 – In-Clinic Blood Draw
- Select your nearest UK clinic and book an appointment.
- A clinician or phlebotomist collects a venous blood sample.
- The sample undergoes specialised clotting assays.
- Results are delivered securely online.
Option 2 – Home or Hotel Phlebotomy (+£60)
- Book a UK-wide home or hotel visit at a convenient time.
- A trained phlebotomist collects your blood sample on-site.
- The sample is transported to the laboratory.
- Results are uploaded digitally without the need to travel.
Your Results Explained
Negative Result
No lupus anticoagulant detected.
This reduces the likelihood of antiphospholipid syndrome at the time of testing.
Borderline / Indeterminate Result
Results are inconclusive.
Repeat testing after 12 weeks may be recommended to confirm persistence.
Positive Result
Lupus anticoagulant detected.
This suggests increased clotting risk and may indicate antiphospholipid syndrome when persistent and clinically correlated.
UK guidance requires repeat positivity at least 12 weeks apart for diagnosis.
How It Works
Simple steps to get your results
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Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.