Lymphocyte Subsets
Private Lymphocyte Subsets blood test in London for £199.99, assessing immune-cell populations with results expected in around 2 business days.
Turnaround time
2 business days
Biomarkers count
1
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Overview of the Lymphocyte Subsets
The Lymphocyte Subsets blood test is a specialist cellular immunology investigation used to characterise important populations of lymphocytes within circulating blood.
The current London Blood Tests product lists 1 biomarker: Lymphocyte Count.
Lymphocytes are white blood cells central to immune defence.
They include several populations with distinct biological roles.
T lymphocytes coordinate cellular immune responses and can be subdivided according to surface markers such as CD3, CD4 and CD8.
CD4 T cells have important helper and regulatory functions.
CD8 T cells can recognise and destroy selected infected or abnormal cells.
B lymphocytes contribute to antibody production, while natural killer cells form part of innate cellular immune defence.
Specialist lymphocyte-subset analysis is performed using flow cytometry, a laboratory technique that identifies cells according to proteins displayed on their surfaces.
The exact subset measurements reported depend on the laboratory test specification.
The specialist TDL assay associated with Lymphocyte Subsets is described as CD3/CD4/CD8, while the current London Blood Tests product catalogue records the product biomarker as Lymphocyte Count.
This means the report itself should be used as the definitive source for exactly which individual cell populations have been quantified.
Lymphocyte Subsets provide substantially more detail than a routine Full Blood Count, which generally reports the overall Lymphocyte Count without characterising individual T-cell populations.
Abnormal subset numbers can occur with infection, immune deficiency, immune-modifying medication, haematological disorders and other clinical conditions.
One abnormal subset result does not independently diagnose an immune disorder.
What Does the Lymphocyte Subsets Test Check?
This test measures 1 listed biomarker.
Lymphocyte Count
Provides the listed lymphocyte biomarker within a specialist Lymphocyte Subsets assessment. The laboratory may additionally characterise T-cell populations using flow-cytometry markers according to the assay performed.
Who May Benefit From the Lymphocyte Subsets Test?
Lymphocyte Subsets testing is generally used when a more detailed assessment of cellular immunity is required than a routine Full Blood Count can provide.
People with recurrent or unusually severe infections - Detailed immune-cell assessment may be appropriate where an immune deficiency is suspected.
People with persistent unexplained lymphopenia - Subset testing can help identify which lymphocyte populations account for a reduced overall count.
People with an unexplained high Lymphocyte Count - Flow cytometry can occasionally provide additional information about immune-cell distribution.
People undergoing specialist immunodeficiency assessment - T-cell populations are important components of cellular immune competence.
People with chronic viral infections under specialist monitoring - Some viral diseases can alter lymphocyte populations.
People taking significant immunosuppressive treatment - Medicines can reduce or alter specific lymphocyte populations.
People receiving chemotherapy or selected biological therapies - Treatment effects may require specialist immune monitoring.
People following transplantation - Lymphocyte populations can be relevant during selected transplant-monitoring pathways.
People with a previous abnormal subset result - Repeat measurement can identify persistent or treatment-related changes.
People specifically advised to obtain Lymphocyte Subsets - The test is most clinically useful when performed for a defined immunological or haematological question.
How to Prepare
Do not stop immunosuppressive treatment solely to alter a Lymphocyte Subsets result.
Because viable blood cells are being assessed, sample transport and timing are more important than for many routine serum tests.
Symptoms and Reasons to Consider the Lymphocyte Subsets Test
There is no symptom specific to an abnormal lymphocyte subset. Testing is usually driven by infection history, treatment or abnormal blood counts.
Recurrent bacterial, viral or fungal infections - Repeated infections can occasionally indicate an underlying immune problem.
Unusually severe infections - Infection severity disproportionate to expected risk may prompt specialist immunology assessment.
Opportunistic infections - Certain infections occurring in an unusual clinical setting can indicate impaired cellular immunity.
Persistent unexplained low Lymphocyte Count - A routine Full Blood Count may identify lymphopenia that requires more detailed characterisation.
Persistent unexplained enlarged lymph nodes with abnormal blood counts - Further haematological investigation may sometimes include flow cytometry.
Monitoring during immunosuppressive treatment - Selected therapies can substantially alter T-cell populations.
A known immune disorder requiring follow-up - Serial subset testing can monitor changes over time.
A previous abnormal CD3, CD4 or CD8 result - Repeat testing can determine whether the abnormality persists.
Recurrent infections and fatigue are not specific to lymphocyte abnormalities and have many potential causes.
Severe or recurrent infections, unexplained weight loss, persistent fever or major blood-count abnormalities should be clinically assessed rather than interpreted from one immune-cell marker alone.
How to Book Your Lymphocyte Subsets Test
The test requires an appropriately handled EDTA blood sample for specialist cellular analysis.
Choose the Lymphocyte Subsets
Select the specialist Lymphocyte Subsets blood test.
Select your sample collection option
Choose a clinic or professional home/hotel collection route capable of timely cellular sample transport.
Attend your appointment
A trained healthcare professional collects the required venous blood specimen.
Laboratory analysis
Your sample undergoes specialist flow-cytometric analysis according to the laboratory Lymphocyte Subsets assay.
Receive your results securely
Your authorised immune-cell report is delivered securely for review with a GP, immunologist, infectious-disease specialist or haematologist where appropriate.
When Will I Receive My Results?
The current London Blood Tests turnaround for Lymphocyte Subsets is approximately 2 business days after your blood sample reaches the laboratory.
The underlying cellular analysis is performed using flow cytometry rather than routine serum biochemistry.
Because the laboratory needs intact cells, the specimen is time-sensitive and requires appropriate EDTA collection and transport.
Once the specimen has been received in suitable condition, cellular analysis, quality review and laboratory authorisation are completed before the report is released.
Delay in transport, unsuitable sample age, clotting within the EDTA tube or another specimen-quality issue can compromise cellular analysis and may require recollection.
For this reason, not every postal or delayed collection route is appropriate for this investigation.
Understanding Your Results
Your report may include an overall Lymphocyte Count together with specific immune-cell populations according to the laboratory assay.
The current specialist laboratory test is associated with CD3, CD4 and CD8 T-cell assessment.
A reduced overall lymphocyte or T-cell population can occur because of acute illness, immunosuppressive treatment, infection, bone-marrow disorders and several immune deficiencies.
A low CD4 count has particular clinical significance in selected immunodeficiency and HIV-monitoring contexts, but the meaning depends on the person's underlying condition.
An increased lymphocyte or subset value can occur with immune activation and certain chronic infections, although persistent abnormalities may require further haematological investigation.
Percentages and absolute cell counts can provide different information.
A normal percentage does not always mean the absolute count is normal if the overall Lymphocyte Count is substantially altered.
The result should therefore be interpreted with the Full Blood Count, clinical history, medication and reason for testing.
Why Book With London Blood Tests?
Private Lymphocyte Subsets testing in London - Access specialist cellular immune assessment privately.
More detailed than a routine FBC - Flow cytometry can characterise selected lymphocyte populations rather than simply reporting total lymphocytes.
Relevant to immune-deficiency assessment - T-cell measurements can contribute to specialist investigations.
Useful during immunosuppressive treatment - Serial immune-cell measurements may support selected monitoring pathways.
Specialist flow-cytometry analysis - The test uses cellular immunophenotyping methodology.
Appropriate sample handling - Collection can be planned around the time-sensitive specimen requirements.
Secure reporting - Receive your authorised immune-cell report securely.
Clear pricing - The Lymphocyte Subsets test costs £199.99.
Private Lymphocyte Subsets Blood Test in London
London Blood Tests provides private Lymphocyte Subsets testing in London for people requiring specialist assessment of cellular immune populations.
The test costs £199.99.
The current product lists one biomarker, Lymphocyte Count, while the specialist laboratory assay can characterise selected T-cell populations using flow cytometry.
Results are expected approximately 2 business days after laboratory receipt.