Understanding the Manganese (Serum) blood test

The Manganese (Serum) blood test measures the concentration of manganese, an essential trace mineral involved in enzyme activity, antioxidant defence, bone formation, metabolism, and nervous system function. Manganese plays a role in activating enzymes that support energy production and protection against oxidative stress.

Both deficiency and excess can have clinical consequences. Low levels may affect bone health and metabolism, while elevated levels can occur with environmental or occupational exposure and may impact neurological function. Serum testing helps evaluate current manganese status in the body.

This test is commonly used in nutritional assessment, investigation of unexplained neurological symptoms, and monitoring of potential exposure from supplements, diet, or the environment.

When a Manganese (Serum) blood test is recommended

This test is recommended when there is a need to assess trace mineral balance or investigate symptoms that may relate to manganese status.

Testing may be appropriate if you:

• Are assessing micronutrient or trace mineral status
• Take supplements containing manganese
• Have unexplained neurological symptoms (e.g., tremor, coordination issues)
• Have occupational or environmental exposure risks
• Have liver disease affecting mineral handling
• Are investigating bone or metabolic health
• Are following a restricted or specialised diet
• Want a comprehensive nutritional assessment

Benefits of the Manganese (Serum) test

Assesses trace mineral status
Evaluates manganese levels accurately.

Supports nutritional optimisation
Helps tailor dietary or supplement strategies.

Identifies potential overexposure
Useful for environmental or occupational monitoring.

Relevant to bone and metabolic health
Manganese supports bone formation and metabolism.

Aids investigation of neurological symptoms
Elevated levels can affect nervous system function.

Simple blood test with no preparation required
No fasting or lifestyle changes needed.

Useful in functional and preventive medicine
Complements broader micronutrient testing.

Provides clinically actionable insight
Guides further testing or intervention if abnormal.

How the test is carried out

We offer two convenient UK-wide testing options:

Clinic-based blood testing

• Choose your nearest UK clinic
• A healthcare professional collects a blood sample
• The sample is analysed in a certified laboratory
• Results are issued once testing is complete

Home or hotel blood collection (+£60)

• A qualified phlebotomist visits your home, workplace, or hotel
• Blood is collected at a time convenient for you
• No clinic visit required
• Available nationwide across the UK

Both options provide the same laboratory accuracy and clinical reliability.

Understanding your Manganese (Serum) test results

Low manganese levels

Low serum manganese may suggest insufficient intake or absorption, which could impact enzyme function, bone health, or metabolism.

Typical UK interpretation:

• Below laboratory reference range

Dietary review or further nutritional assessment may be recommended.

Normal manganese levels

Normal levels indicate adequate manganese status at the time of testing.

Typical UK interpretation:

• Within laboratory reference range

No action is usually required unless symptoms persist.

High manganese levels

Elevated manganese levels may indicate excess intake or exposure, potentially associated with neurological effects, especially with chronic exposure.

Typical UK interpretation:

• Above laboratory reference range

Clinical correlation and exposure assessment may be advised.