MSM2 STI
Advanced multi-site STI screening using blood, urine, throat and rectal samples, including HIV, syphilis, hepatitis and PCR testing.
Turnaround time
3 business days
Biomarkers count
11
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Overview of the MSM2 STI Test
The MSM2 STI is an advanced multi-site sexual health profile combining blood serology, urine PCR and throat and rectal PCR testing.
The profile includes HIV 1 & 2/p24 Antigen, Syphilis IgG/IgM, Hepatitis B Surface Antigen and Hepatitis C Antibodies.
It also contains a seven-STI PCR screen covering Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasma urealyticum/parvum, Trichomonas vaginalis, Gardnerella vaginalis and Herpes Simplex I/II.
Additional Chlamydia and Gonorrhoea testing is performed from throat and rectal specimens.
A Macrolide Resistance Test is included when relevant to Mycoplasma genitalium.
The profile therefore provides considerably broader coverage than the MSM1 STI profile.
Because throat and rectal swabs are required, the complete MSM2 STI follows a clinic collection pathway with clinic collection only. The MSM2 STI costs £576.
What Does the Atypical Pneumonia Screen Check ?
The MSM2 profile combines blood-borne infection screening with urine and multi-site PCR testing.
HIV 1 & 2/p24 Antigen - Combined HIV screening detecting HIV-1/HIV-2 antibodies together with p24 antigen.
Syphilis IgG/IgM - Detects antibodies associated with Treponema pallidum infection.
Hepatitis B Surface Antigen - Screens for HBsAg associated with current Hepatitis B infection.
Hepatitis C Antibodies - Detects antibodies associated with previous or current Hepatitis C exposure.
Chlamydia trachomatis - Molecular testing for Chlamydia infection from the principal PCR specimen.
Neisseria gonorrhoeae - Molecular testing for Gonorrhoea.
Mycoplasma genitalium - PCR testing for M. genitalium.
Ureaplasma urealyticum/parvum - Molecular testing for Ureaplasma species included in the panel.
Trichomonas vaginalis - PCR testing for Trichomonas.
Gardnerella vaginalis - Molecular detection of Gardnerella vaginalis.
Herpes Simplex I/II - PCR testing for HSV-1 and HSV-2 within the seven-STI screen.
Chlamydia trachomatis - Throat - Site-specific pharyngeal Chlamydia testing.
Chlamydia trachomatis - Rectal - Site-specific rectal Chlamydia testing.
Neisseria gonorrhoeae - Throat - Site-specific pharyngeal Gonorrhoea testing.
Neisseria gonorrhoeae - Rectal - Site-specific rectal Gonorrhoea testing.
Macrolide Resistance Test - Mycoplasma genitalium - Resistance testing used within the M. genitalium pathway where applicable.
Who May Benefit From the MSM2 STI Test?
MSM2 may be useful for people wanting one of the broadest combined multi-site sexual-health profiles available through the laboratory.
Men who have sex with men seeking comprehensive screening - Blood, urine, throat and rectal sites are assessed.
People with oral and anal sexual exposure - Site-specific throat and rectal testing is included.
People wanting Hepatitis B and Hepatitis C screening alongside STI testing - Both form part of MSM2.
People wanting broader PCR testing than Chlamydia and Gonorrhoea alone - Seven PCR organisms are included.
People concerned about Mycoplasma genitalium - M. genitalium and macrolide-resistance testing form part of the pathway.
People with a new sexual partner or multiple partners - Comprehensive screening may be appropriate depending on exposure.
People with no symptoms who want broad screening - Many STIs can be asymptomatic.
How to Prepare
Recent antibiotic treatment may influence some infection results.
Do not delay medical assessment where severe pain, fever, significant swelling or other acute symptoms are present.
Symptoms and Reasons to Consider the MSM2 STI Test
MSM2 may be appropriate after relevant sexual exposure whether symptoms are present or not.
Pain or burning when urinating - Can occur with several sexually transmitted infections.
Genital or urethral discharge - May justify molecular STI testing.
Rectal pain, discharge or bleeding - Rectal Chlamydia and Gonorrhoea testing may be relevant.
Persistent throat symptoms after relevant exposure - Pharyngeal STI testing may be appropriate.
Genital lesions or sores - HSV and Syphilis may form part of the differential.
A known contact with an STI - Broad testing may be appropriate according to exposure.
No symptoms but concern following sexual exposure - Asymptomatic infection is possible.
Different infections have different testing windows.
Very recent exposure may require repeat testing even when an initial result is negative.
How to Book Your MSM2 STI Test
MSM2 requires several specimen types and therefore follows a professional multi-site clinic collection pathway.
Choose the MSM2 STI Test
Select the advanced multi-site sexual health profile (test price £576).
Select your sample collection option
Book required in-clinic multi-site specimen collection (+£35 clinic collection fee).
Attend your appointment
Blood, urine, throat and rectal specimens are obtained as required.
Laboratory analysis
Serology and multi-site PCR testing are performed using the relevant laboratory methods.
Receive your results securely
Your complete confidential sexual-health report is returned securely.
When Will I Receive My Results?
Results are generally expected within approximately 3 days.
Positive Mycoplasma genitalium findings requiring resistance analysis or other confirmatory work can occasionally affect final reporting.
Understanding Your Results
Each infection and anatomical site is reported according to the corresponding laboratory assay.
A negative urine result does not determine what is present at the throat or rectum, which is why site-specific swabs are included.
Reactive HIV, Hepatitis or Syphilis screening results may require confirmatory investigation.
A positive PCR result indicates that genetic material from the corresponding organism has been detected.
Positive STI results should receive appropriate clinical review so treatment and partner-management advice can be arranged.
Why Book With London Blood Tests?
London Blood Tests provides access to one of the most comprehensive multi-site sexual-health profiles within the specialist laboratory pathway.
Blood, urine, throat and rectal testing - Several specimen types are combined.
HIV and Syphilis included - Core blood-borne STI screening forms part of the profile.
Hepatitis B and C included - Viral-hepatitis screening is incorporated.
Seven-STI PCR screen - Multiple bacterial, protozoal and viral targets are included.
Additional throat and rectal testing - Chlamydia and Gonorrhoea are assessed at relevant anatomical sites.
Mycoplasma genitalium resistance pathway - Macrolide Resistance testing is included where applicable.
Approximately 3-day turnaround - Results are generally expected within the stated timeframe.
Private MSM2 STI Test in London
London Blood Tests provides private MSM2 STI screening in London.
The profile combines blood serology with urine, throat and rectal PCR testing.
Because site-specific swabs are required, the complete MSM2 test is clinic collection only.
Results are generally expected within approximately three days.