What is the Mycology / Skin Scrapings by PCR test?

The Mycology / Skin Scrapings by PCR test uses polymerase chain reaction (PCR) technology to detect fungal genetic material from skin scrapings, nail clippings, or hair samples. It identifies dermatophytes, yeasts, and other fungi responsible for superficial fungal infections.

PCR testing is significantly more sensitive than traditional microscopy and culture. It can detect fungal infection even when organisms are present in very low numbers or when previous treatments have partially suppressed growth.

This test is used for accurate diagnosis when fungal infection is suspected but difficult to confirm.

Why do I need a Mycology / Skin Scrapings PCR test?

Fungal skin, nail, and scalp infections can mimic other dermatological conditions and may not respond to treatment if misdiagnosed.

You may need this test if you have:

• Persistent or recurrent skin rashes

• Itchy, scaly, or cracked skin

• Thickened, discoloured, or brittle nails

• Nail separation from the nail bed

• Scalp scaling or hair loss

• Skin lesions not responding to treatment

• Suspected fungal infection before starting antifungal therapy

Accurate identification helps guide appropriate treatment and avoids unnecessary or ineffective therapies.

Benefits of the test

1. Highly sensitive fungal detection
   Identifies infection even at low levels.

2. Faster than traditional culture
   Reduces diagnostic delay.

3. Accurate species identification
   Supports targeted antifungal treatment.

4. Useful after failed treatment
   Detects infection despite partial suppression.

5. Non-invasive sample collection
   Simple skin scraping or nail sample.

6. Reduces misdiagnosis
   Differentiates fungal from non-fungal conditions.

7. Widely used in dermatology
   Accepted diagnostic method.

8. Improves treatment outcomes
   Enables correct therapy selection.

Step-by-step: How we offer testing

Clinic-based testing (UK-wide)

• Choose your nearest UK clinic

• Skin, nail, or hair sample collected

• Sample sent to the laboratory for PCR analysis

• Results issued once testing is complete

Home or hotel collection (+£60, UK-wide)

• Sample collection arranged where appropriate

• Sample securely transported to the laboratory

Your results explained

Negative result

• No fungal DNA detected

• Suggests no active fungal infection in the sampled area

Positive result

• Fungal DNA detected

• Confirms fungal infection

• May specify dermatophyte, yeast, or other fungal species

Results should be interpreted alongside clinical appearance and symptoms.