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Needle Stick Injury Profile

Viral & Bacterias Screen
149.00

Private Needle Stick Injury Profile in London for £149, assessing source blood-borne virus markers with results expected in around 1 day.

Turnaround time

1 business day

Biomarkers count

4

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Overview of the Needle Stick Injury Profile Test

The Needle Stick Injury Profile is a source or donor blood-borne virus screen used after a sharps, needlestick or significant blood exposure.

The profile assesses three infectious-disease markers and includes storage of serum for two years.

The tested infections are Hepatitis B, Hepatitis C and HIV.

Needlestick and sharps injuries can expose healthcare workers and others to blood-borne viruses when contaminated blood penetrates the skin.

The actual transmission risk depends on several factors, including the type and depth of injury, the amount of blood involved and whether the source has a transmissible infection.

This laboratory profile is specifically described by the referral laboratory as “Donor – Not recipient”.

It therefore assesses the source person's blood where source testing is appropriate and consent and clinical procedures permit it.

The screen includes Hepatitis B Surface Antigen, Hepatitis C Antibodies and HIV 1 & 2/p24Ag.

Serum is also saved for two years.

A negative source screen can provide useful information during occupational-health risk assessment.

However, negative results do not completely eliminate risk if the source infection is extremely recent and still within a diagnostic window period.

The exposed person still requires their own clinical risk assessment and follow-up testing according to the exposure circumstances.

This is especially important for HIV because post-exposure prophylaxis is time-sensitive.

Testing must never delay urgent occupational-health, sexual-health or emergency medical assessment.

What Does the Needle Stick Injury Profile Contain?

The profile tests the source or donor for three major blood-borne virus markers and includes serum storage. This profile measures 3 infectious-disease biomarkers plus serum storage.

Blood-Borne Virus Screening
Hepatitis B Surface Antigen

Detects Hepatitis B surface antigen, providing evidence of current Hepatitis B infection when present.

Hepatitis C Antibodies

Detects antibodies associated with Hepatitis C exposure and can indicate the need for further HCV RNA testing.

HIV 1 & 2/p24Ag

Uses combined HIV antibody and p24 antigen testing to screen for HIV-1 and HIV-2 infection.

Sample Storage
Serum saved for 2 years

A serum sample is retained by the laboratory for potential additional testing related to the exposure pathway.

Who May Benefit From the Needle Stick Injury Profile Test?

The profile is designed specifically for testing the source or donor following a potentially significant occupational or accidental blood exposure.

A source patient following a healthcare needlestick incident - Source testing can provide important information for the exposed healthcare worker's risk assessment.

A donor or source following a sharps injury - The profile screens for HIV, Hepatitis B and Hepatitis C markers.

Healthcare organisations managing an occupational blood exposure - Rapid source information can help guide the wider post-exposure pathway.

A source following blood contact with broken skin - Significant blood exposure can occur without a conventional needle injury.

A source following blood exposure to the eyes or mouth - Mucous-membrane exposure can require formal risk assessment.

People involved in an exposure incident where source testing has been clinically authorised - Testing should follow appropriate consent and occupational-health procedures.

A known source whose infection status is uncertain - Laboratory screening can provide objective blood-borne virus information.

A source being tested while the exposed person undergoes separate baseline assessment - Source and recipient testing are different components of the post-exposure pathway.

How to Prepare

Fasting
Fasting is not required.
Source identification
Confirm that the sample is being collected from the source or donor rather than being used as the exposed recipient's complete follow-up profile.
Consent
Appropriate consent for source blood-borne virus testing should be obtained according to the clinical or occupational-health pathway.
Exposure timing
Record the exact date and approximate time of the needlestick, sharps injury or blood exposure.
Exposure type
Record whether the event involved a hollow-bore needle, other sharp, broken skin or mucous-membrane exposure.
Known infection history
Provide relevant known HIV, Hepatitis B or Hepatitis C information where available.
Medication
Routine medication does not usually require alteration before source serology.
Previous results
Previous HIV, Hepatitis B or Hepatitis C laboratory results can provide additional context.
Recipient assessment
Ensure the exposed person is undergoing their own urgent clinical risk assessment and baseline testing.

This profile is for source/donor testing and is not a substitute for testing the exposed recipient.

The exposed person may require baseline and follow-up HIV, Hepatitis B and Hepatitis C testing according to the nature of the incident and current clinical guidance.

Symptoms and Reasons to Consider the Needle Stick Injury Profile Test

This profile is usually requested because an exposure incident has occurred, rather than because the source person has symptoms. HIV, Hepatitis B and Hepatitis C can all be present without obvious symptoms.

A needlestick injury involving blood from a known source - Source screening can help determine whether HIV, Hepatitis B or Hepatitis C exposure may have occurred.

A cut from a blood-contaminated sharp instrument - Sharps injuries can create a route for blood-borne virus transmission.

Blood exposure to broken or damaged skin - Significant contact can require formal occupational-health assessment.

Blood splashed into the eyes - Mucous-membrane exposure can carry blood-borne virus risk.

Blood splashed into the mouth or other mucous membrane - This can also require post-exposure assessment.

An occupational blood exposure involving a source with unknown infection status - Rapid source screening can provide useful information.

A source with known risk factors for blood-borne infection - Testing can clarify current laboratory status.

An exposure where HIV post-exposure prophylaxis is being considered - Source testing can contribute to risk assessment but must not delay treatment decisions.

A needlestick or significant blood exposure requires urgent medical or occupational-health assessment even when the source appears well and has no symptoms.

The wound should be washed with running water and soap, covered appropriately and reported through the relevant workplace or clinical pathway.

If there is a possible HIV exposure, urgent assessment for post-exposure prophylaxis is required. PEP should be started as soon as clinically indicated and must not be delayed while waiting for the source blood-test result.

How to Book Your Needle Stick Injury Profile Test

The Needle Stick Injury Profile can be arranged privately when source blood needs to be tested following a potentially significant exposure incident.

1
Choose the Needle Stick Injury Profile

Select the source/donor blood-borne virus screening profile.

2
Select your sample collection option

Arrange prompt professional venous blood collection in a pathway appropriate to the exposure incident.

3
Attend your appointment

A trained healthcare professional collects the required source blood samples after appropriate consent.

4
Laboratory analysis

The sample undergoes Hepatitis B Surface Antigen, Hepatitis C Antibody and HIV 1 & 2/p24Ag testing.

5
Receive your results securely

The authorised source results are returned securely for use within the occupational-health or post-exposure management pathway.

When Will I Receive My Results?

The current specialist laboratory turnaround for the Needle Stick Injury Profile is approximately 1 day after laboratory receipt.

The laboratory currently lists the profile specifically as Donor – Not recipient and retains serum for 2 years.

Urgent clinical decisions, particularly those involving HIV post-exposure prophylaxis, should not wait for routine laboratory reporting.

Understanding Your Results

A negative source profile means the included HIV, Hepatitis B and Hepatitis C screening markers were not detected in the submitted source sample.

This substantially informs the exposure assessment.

However, a negative result does not absolutely exclude a very recent infection that has not yet become detectable.

A positive Hepatitis B Surface Antigen result indicates evidence consistent with current Hepatitis B infection and requires appropriate clinical confirmation and follow-up.

A positive Hepatitis C Antibody result indicates previous or current exposure to Hepatitis C.

HCV RNA testing is generally required to establish whether active infection is present.

A reactive HIV 1 & 2/p24Ag result requires confirmatory testing through the appropriate HIV diagnostic pathway.

The exposed person's management also depends on the nature of the exposure, source findings, Hepatitis B vaccination or immunity status and other clinical factors.

Recipient follow-up testing remains necessary where the exposure is considered clinically significant.

Why Book With London Blood Tests?

London Blood Tests provides rapid private source testing following potentially significant occupational or accidental blood exposure.

Screens the major blood-borne viruses - HIV, Hepatitis B and Hepatitis C screening markers are included.

Designed specifically for source testing - The specialist laboratory identifies the profile as donor rather than recipient testing.

Rapid specialist turnaround - Results are expected approximately 1 day after laboratory receipt.

Includes fourth-generation HIV screening - HIV antibodies and p24 antigen are assessed together.

Includes Hepatitis B Surface Antigen - The profile screens for evidence relevant to current Hepatitis B infection.

Includes Hepatitis C Antibodies - Previous or current exposure can be identified and followed by HCV RNA where required.

Serum is retained for 2 years - Additional testing related to the incident may therefore be possible.

Clear pricing - The Needle Stick Injury Profile costs £149.

Private Needle Stick Injury Profile Blood Test in London

London Blood Tests provides private Needle Stick Injury Profile testing for source or donor assessment after needlestick, sharps or other significant blood exposure.

The profile costs £149 and includes 3 blood-borne virus screening biomarkers plus serum storage.

Results are expected approximately 1 day after laboratory receipt.

The test does not replace urgent assessment, baseline testing or follow-up of the exposed recipient.

Frequently Asked Questions

The specialist laboratory identifies this as a source or donor profile rather than the exposed recipient's complete post-exposure testing programme.

The profile screens for HIV, Hepatitis B and Hepatitis C.

Hepatitis B Surface Antigen is included.

Hepatitis C Antibodies are included.

The profile uses combined HIV 1 & 2 antibody and p24 antigen screening.

Not necessarily. Management depends on the type of exposure, timing, source results and the exposed person's clinical circumstances.

Wash the wound with running water and soap, cover it appropriately, report the incident and seek urgent medical or occupational-health advice.

No. Assessment for HIV PEP is time-sensitive and should not be delayed while awaiting laboratory results.

Not necessarily. HCV RNA testing is generally required to determine whether active infection is present.

Yes. The specialist laboratory currently states that serum is saved for 2 years.

No.

The current specialist laboratory turnaround is approximately 1 day after laboratory receipt.
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