NK Assay/Cytotoxicity Panel
The NK Assay / Cytotoxicity Panel measures how effectively natural killer cells destroy infected or abnormal cells. It provides functional insight into immune system performance.
Turnaround time
1 week
Biomarkers count
1
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Details about NK Assay/Cytotoxicity Panel
What is the NK Assay / Cytotoxicity Panel?
The NK Assay / Cytotoxicity Panel is a functional immune test that evaluates the activity of natural killer (NK) cells, a critical part of the innate immune system. Rather than just counting NK cells, this test measures how effectively they can identify and destroy virus-infected or abnormal cells.
NK cells play a key role in early antiviral defence, cancer surveillance, and immune regulation. Reduced cytotoxic activity may be present even when NK cell numbers are normal, making functional testing essential in selected clinical contexts.
Why do I need an NK Cytotoxicity test?
Standard immune tests often measure cell numbers but do not assess how well those cells function. The NK assay provides deeper immune insight.
You may benefit from this test if you:
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Have recurrent or persistent viral infections
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Experience chronic fatigue or immune dysfunction
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Have unexplained immune suppression
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Are being investigated for immune dysregulation
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Have suspected post-viral syndromes
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Are undergoing immune system assessment
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Require advanced immune profiling
The test helps determine whether immune defence is functioning effectively at a cellular level.
Benefits of the test
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Measures immune function, not just cell count
Assesses real-world NK cell activity. -
Supports investigation of recurrent infections
NK cells are critical in viral defence. -
Provides insight into immune surveillance
Important in tumour and abnormal cell detection. -
Useful in complex immune presentations
Adds depth beyond routine immune tests. -
Specialised immune assessment
Not captured by standard blood panels. -
Supports personalised immune evaluation
Helps guide further immune investigation. -
Widely used in immunology research and clinics
Accepted functional immune assay. -
Single blood-based test
Requires one carefully handled sample.
Step-by-step: How we offer testing
Clinic-based testing (UK-wide)
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Choose your nearest UK clinic
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Attend your appointment
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Blood sample taken and processed promptly
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Sample sent to a specialist laboratory
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Results issued once analysis is complete
Home or hotel visit (+£60, UK-wide)
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Mobile phlebotomist attends your location
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Blood sample taken with strict handling requirements
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Sample transported rapidly to the laboratory
Due to the functional nature of the test, strict sample timing and handling are essential.
Your results explained
Low NK cytotoxic activity
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Reduced ability of NK cells to destroy target cells
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May be associated with viral susceptibility or immune suppression
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Requires interpretation with symptoms and immune markers
Normal NK cytotoxic activity
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NK cell function within expected range
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Suggests intact innate immune defence
High NK cytotoxic activity
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Increased NK cell activity
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May be seen in immune activation or inflammation
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Requires clinical correlation
Reference ranges vary by laboratory and assay method.
How It Works
Simple steps to get your results
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.