Oestradiol
The Oestradiol test measures the main form of oestrogen in the body. It helps assess hormonal balance, reproductive health, and endocrine function.
Turnaround time
1-2 days
Biomarkers count
1
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Details about Oestradiol
What is the Oestradiol test?
The Oestradiol (E2) test measures levels of oestradiol, the most biologically active form of oestrogen. Oestradiol is produced mainly by the ovaries in women, the testes in men, and in smaller amounts by adrenal tissue and fat cells.
This hormone plays a key role in the menstrual cycle, ovulation, bone health, cardiovascular function, mood regulation, and sexual development. In men, oestradiol is important for bone density, libido, and overall hormonal balance.
The test is used in both women and men to assess endocrine and reproductive health.
Why do I need an Oestradiol test?
Oestradiol imbalance can cause a wide range of symptoms and may affect fertility, menstrual regularity, and overall wellbeing.
You may benefit from this test if you:
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Have irregular or absent periods
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Are investigating fertility or ovulation
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Experience menopausal or perimenopausal symptoms
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Have symptoms of hormonal imbalance
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Are monitoring hormone therapy
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Have reduced libido or mood changes
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Are assessing pubertal or endocrine disorders
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Are monitoring testosterone-related balance (in men)
Testing helps determine whether symptoms are linked to oestrogen levels.
Benefits of the test
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Assesses oestrogen status accurately
Measures the primary active oestrogen. -
Supports fertility and cycle assessment
Useful in ovulation and menstrual evaluation. -
Helps assess menopausal status
Low levels are typical after menopause. -
Important in hormone therapy monitoring
Used in HRT and endocrine follow-up. -
Relevant for men’s hormone balance
Helps assess oestrogen–testosterone balance. -
Supports bone and cardiovascular health assessment
Oestrogen plays a protective role. -
Simple blood-based testing
Requires only one blood sample. -
Widely used in clinical endocrinology
Standard hormone assessment.
Step-by-step: How we offer testing
Clinic-based testing (UK-wide)
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Choose your nearest UK clinic
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Attend your appointment
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Blood sample taken by a clinician
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Sample sent to the laboratory
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Results issued once analysis is complete
Home or hotel visit (+£60, UK-wide)
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Mobile phlebotomist attends your location
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Blood sample taken at home or hotel
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Sample securely transported to the laboratory
Your results explained
Low oestradiol
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May indicate ovarian insufficiency, menopause, or pituitary causes
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In men, may affect bone health and libido
Typical UK reference examples (vary by lab):
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Postmenopausal women: <110 pmol/L
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Men: <40 pmol/L
Normal oestradiol
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Indicates expected hormone production for age and cycle phase
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Supports normal reproductive and endocrine function
Reference ranges vary widely depending on menstrual cycle phase
High oestradiol
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May be seen in pregnancy, ovarian stimulation, or hormone therapy
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In men, may contribute to symptoms such as gynaecomastia
Interpretation must consider cycle timing, medications, and clinical context
How It Works
Simple steps to get your results
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.