Pituitary Function Profile
A six-marker pituitary profile assessing thyroid, reproductive, growth and adrenal signalling through TSH, FSH, LH, prolactin, IGF-1 and cortisol.
Turnaround time
1 business day
Biomarkers count
6
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Overview of the Pituitary Function Profile Test
The Pituitary Function Profile is a six-marker blood test assessing hormonal pathways regulated by the pituitary gland, including thyroid, reproductive, growth-related and adrenal signalling.
The pituitary is a small endocrine gland located at the base of the brain. Despite its size, it has an important role in controlling several other hormone-producing glands throughout the body.
This profile measures Thyroid Stimulating Hormone, Follicle Stimulating Hormone, Luteinising Hormone, Prolactin, IGF-1 and Cortisol.
Together, these markers provide information about several interconnected endocrine pathways rather than focusing on one hormone alone.
IGF-1 provides information related to growth hormone activity over time and is generally more stable than a random Growth Hormone measurement, which can fluctuate markedly throughout the day.
Cortisol adds information about adrenal hormone production, while TSH reflects pituitary signalling to the thyroid. FSH and LH assess reproductive endocrine signalling, and Prolactin can provide further information where menstrual, fertility, sexual or pituitary-related symptoms are present.
The Pituitary Function Profile costs £169.
Professional blood collection is available in clinic for an additional £35 or through an at-home phlebotomy visit for an additional £60.
What Does the Pituitary Function Profile Test Check?
The Pituitary Function Profile measures 6 biomarkers across several major endocrine pathways.
Thyroid Stimulating Hormone
Measures TSH, the pituitary hormone responsible for regulating thyroid hormone production.
Follicle Stimulating Hormone
Measures FSH, a pituitary hormone involved in ovarian follicle development in women and sperm production in men.
Luteinising Hormone
Measures LH, which contributes to ovulation and ovarian hormone production in women and Testosterone production in men.
Prolactin
Measures a pituitary hormone involved in breast function, reproduction and regulation of the reproductive hormone axis.
IGF-1 (Somatomedin)
Measures Insulin-Like Growth Factor 1, a relatively stable marker used when assessing growth hormone activity.
Cortisol
Measures a major adrenal hormone whose production is regulated through the hypothalamic-pituitary-adrenal axis.
Who May Benefit From the Pituitary Function Profile Test?
The profile may be useful where symptoms involve several hormonal systems or where pituitary function requires broader assessment.
People with unexplained hormonal symptoms affecting several systems - The profile assesses thyroid, reproductive, growth-related and adrenal pathways together.
People with irregular or absent menstrual cycles - FSH, LH and Prolactin can provide useful hormonal information.
People experiencing fertility problems - Pituitary hormones play an important role in reproductive function in both women and men.
People with reduced libido or sexual dysfunction - Abnormal pituitary hormone signalling can sometimes contribute.
People with abnormal Prolactin results - A broader pituitary assessment may provide additional context.
People with unexplained changes in growth-hormone-related markers - IGF-1 provides information about longer-term growth hormone activity.
People with unusual thyroid results - TSH abnormalities may occasionally require assessment within the wider pituitary context.
People undergoing endocrine investigation - The profile can provide a useful multi-axis hormonal overview.
How to Prepare
Hormone results should be interpreted according to time of day, sex, age, menstrual-cycle stage where relevant, medication and clinical history.
Do not stop steroid or hormone treatment without medical advice.
Symptoms and Reasons to Consider the Pituitary Function Profile Test
Pituitary disorders can affect several hormone systems, which means symptoms can vary considerably.
Persistent unexplained fatigue or weakness - Thyroid, adrenal and reproductive hormone pathways can all influence energy.
Irregular or absent periods - FSH, LH and Prolactin may provide useful information.
Reduced libido - Pituitary and reproductive hormone signalling may be relevant.
Difficulty conceiving - FSH, LH and Prolactin can form part of reproductive assessment.
Unexpected breast milk production - Raised Prolactin is one possible cause.
Unexplained changes in body composition or growth-related features - IGF-1 may provide additional endocrine information.
Persistent headaches with hormonal symptoms - Clinical assessment may be required where pituitary disease is being considered.
Visual disturbance associated with headaches or endocrine symptoms - This requires medical assessment rather than relying on blood testing alone.
Severe headache with sudden visual change, collapse, confusion or significant neurological symptoms requires urgent medical assessment.
This blood profile can identify abnormal hormone patterns but cannot diagnose a structural pituitary lesion. Imaging and specialist endocrine assessment may be required where clinically indicated.
How to Book Your Pituitary Function Profile Test
The Pituitary Function Profile can be booked privately with professional venous blood collection.
Choose the Pituitary Function Profile
Select the £169 six-marker endocrine profile.
Select your collection option
Choose in-clinic phlebotomy for +£35 or an at-home phlebotomy visit for +£60.
Attend your appointment
A trained healthcare professional collects the required blood specimens and records the collection time.
Laboratory analysis
TSH, FSH, LH, Prolactin, IGF-1 and Cortisol are measured.
Receive your results securely
Your completed Pituitary Function Profile is delivered securely.
When Will I Receive My Results?
Results are generally expected within approximately 1 working day after the required samples reach the laboratory.
Occasional repeat or confirmatory analysis can extend the final reporting time.
Understanding Your Results
Pituitary hormone results should be interpreted as a pattern rather than independently.
TSH reflects pituitary signalling to the thyroid, although thyroid hormones may also be required for complete interpretation.
FSH and LH vary according to sex, age and menstrual-cycle stage.
Prolactin can temporarily increase because of stress, exercise, sleep, medication and other physiological factors.
IGF-1 is interpreted according to age and provides information related to growth hormone activity.
Cortisol depends strongly on time of day, medication and physiological stress.
An abnormal result does not automatically mean that the pituitary gland is diseased. Further hormone testing, repeat sampling, dynamic endocrine testing or imaging may be required.
Why Book With London Blood Tests?
London Blood Tests provides a focused multi-axis endocrine profile with flexible professional blood collection.
Six endocrine biomarkers - Several pituitary-regulated hormone pathways are assessed together.
IGF-1 included - Growth hormone activity is assessed using a more stable related marker.
Reproductive hormones included - FSH, LH and Prolactin are measured.
Thyroid regulation included - TSH provides information about pituitary signalling to the thyroid.
Cortisol included - Adrenal-axis information forms part of the profile.
Flexible phlebotomy - Choose in-clinic collection for +£35 or an at-home phlebotomist for +£60.
Fast turnaround - Results are generally expected in approximately one working day.
Clear pricing - The Pituitary Function Profile costs £169, with collection charged separately.
Private Pituitary Function Profile Blood Test in London
London Blood Tests provides the Pituitary Function Profile for £169.
The profile measures six markers covering thyroid, reproductive, growth-related and adrenal endocrine pathways.
Professional collection is available in clinic for +£35 or through an at-home phlebotomy visit for +£60.
Results are generally expected within approximately one working day.