What is the Prostate Profile?

The Prostate Profile is an advanced blood test designed to assess prostate health and stratify prostate cancer risk more accurately than PSA testing alone. It evaluates prostate-specific markers alongside inflammatory and growth-related biomarkers.

This profile includes:

• Total Prostate Specific Antigen (Total PSA)

• Free Prostate Specific Antigen (Free PSA)

• Interleukin-8 (IL-8)

• Monocyte Chemotactic Protein-1 (MCP-1)

• Epidermal Growth Factor (EGF)

• Prostate Cancer Risk Score

By combining PSA fractions with inflammatory and cellular signalling markers, this profile provides a more nuanced assessment of prostate disease risk.

Why do I need a Prostate Profile?

PSA levels alone cannot always distinguish between benign prostate enlargement, inflammation, and prostate cancer. The Prostate Profile adds biological context by assessing inflammation and growth signalling associated with malignant progression.

This test is particularly useful for men with borderline or elevated PSA, family history of prostate cancer, or urinary symptoms where clarity is needed before further investigation.

You may benefit from this test if you experience:

• Elevated or rising PSA levels

• Family history of prostate cancer

• Urinary symptoms (poor flow, urgency, nocturia)

• Benign prostatic enlargement

• Prostate inflammation or infection history

• Previous inconclusive prostate tests

• Desire for advanced prostate risk assessment

• Monitoring prostate health over time

Benefits of the Prostate Profile

1. Improves prostate cancer risk stratification
   Goes beyond PSA to assess biological risk.

2. Differentiates benign vs malignant patterns
   Helps distinguish inflammation from cancer-related activity.

3. Reduces unnecessary invasive procedures
   Supports informed decisions about biopsy or imaging.

4. Assesses inflammatory drivers
   IL-8 and MCP-1 reflect prostate inflammation and immune activity.

5. Evaluates growth signalling pathways
   EGF provides insight into cellular proliferation risk.

6. Supports personalised prostate monitoring
   Useful for active surveillance strategies.

7. Adds clarity to borderline PSA results
   Particularly valuable when PSA results are inconclusive.

8. Non-invasive advanced prostate assessment
   Requires only a blood sample.

Step-by-step – how we offer Prostate Profile testing

Clinic-based testing (UK-wide)

• Choose your nearest UK clinic

• Attend your appointment

• Blood sample collected by a qualified clinician or phlebotomist

• Sample is sent to the laboratory for analysis

At-home or hotel testing (+£60)

• A qualified phlebotomist visits your home or hotel

• Blood sample collected in a comfortable, familiar setting

• No clinic visit or travel required

Both services are available UK-wide.

Your Prostate Profile results explained

Low-risk profile

Results indicate low prostate cancer risk, with PSA fractions and inflammatory markers within reassuring ranges. This pattern is more consistent with benign prostate conditions or stable prostate health.

Routine monitoring may be sufficient.

UK reference interpretation:

• Low risk: Within low-risk scoring range

Intermediate-risk profile

Findings suggest increased biological activity or inflammation that may warrant closer monitoring. PSA ratios or inflammatory markers may be borderline or mildly elevated.

Further assessment or repeat testing may be considered.

UK reference interpretation:

• Intermediate risk: Moderate-risk scoring range

High-risk profile

Results indicate elevated prostate cancer risk based on combined PSA, inflammatory markers, and growth factor activity. This pattern suggests increased likelihood of malignant processes.

Specialist referral and further diagnostic evaluation may be advised.

UK reference interpretation:

• High risk: High-risk scoring range