1,25-dihydroxyvitamin D (calcitriol)
This test measures 1,25-dihydroxyvitamin D, the biologically active form of vitamin D. It is used to investigate calcium imbalance, kidney disease and...
Prostate PSA Profile
89.00
This test evaluates key prostate markers linked to enlargement, inflammation, and cancer risk. It helps distinguish benign prostate issues from more serious conditions.
Turnaround time
1-2 days
Biomarkers count
3
Same-Day Appointments
UKAS Accredited Labs
Book your test
Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Prostate PSA Profile
What is a Prostate PSA Profile?
The Prostate PSA Profile is a specialised blood test used to assess prostate gland health in men. It measures three important markers that provide more detail than a standard PSA test alone.
This profile includes:
• Total Prostate Specific Antigen (PSA)
• Free Prostate Specific Antigen (Free PSA)
• Free-to-Total PSA Ratio
PSA is a protein produced by the prostate gland. Elevated levels may occur due to prostate enlargement, inflammation, infection, or prostate cancer. Measuring Free PSA and calculating the ratio improves the accuracy of interpretation.
Why do I need a Prostate PSA Profile?
Prostate conditions are common in men over 40 and often develop without obvious symptoms. A simple PSA test can sometimes be misleading, as PSA may rise in non-cancerous conditions.
This profile helps doctors better understand the reason behind a raised PSA.
Reasons for testing include:
• Age over 40 as routine screening
• Family history of prostate cancer
• Difficulty urinating or weak urine flow
• Frequent urination, especially at night
• Pelvic discomfort
• Monitoring known prostate enlargement (BPH)
• Follow-up after previous raised PSA
• Monitoring after prostate treatment
Early detection greatly improves treatment outcomes.
Benefits of the test
1. More accurate than PSA alone
Free PSA ratio helps distinguish benign from suspicious causes.
2. Early detection of prostate cancer risk
Helps identify when further investigation is needed.
3. Detects prostate enlargement (BPH)
Common non-cancerous cause of raised PSA.
4. Identifies prostate inflammation or infection
PSA rises in prostatitis.
5. Supports monitoring over time
Useful for tracking PSA trends.
6. Non-invasive screening method
Simple blood test with high clinical value.
7. Supports decision for further tests
Guides need for MRI or urology referral.
8. Important for men over 40
Risk increases significantly with age.
Expanded benefit explanation
PSA can be elevated for several reasons. Measuring Free PSA and calculating the ratio improves interpretation and reduces unnecessary anxiety or invasive investigations.
Step-by-step — How testing works
We offer two UK-wide testing options:
Clinic testing
• Choose your nearest UK clinic
• Attend your appointment
• Blood sample collected by clinician
• Sample analysed in laboratory
• Results securely returned
Home or hotel visit (+£60)
• Phlebotomist visits your home, office, or hotel
• Blood sample collected safely
• No need to travel
• Sample transported to laboratory
• Results delivered confidentially
Both services are available UK-wide.
Your results explained
Low levels
• Total PSA: <3.0 ng/mL (age dependent)
• Free PSA ratio: >25%
Interpretation:
Low risk of prostate disease.
Normal / borderline levels
• Total PSA: 3.0–4.0 ng/mL
• Free PSA ratio: 15–25%
Interpretation:
May reflect benign enlargement or early change. Monitoring recommended.
High levels
• Total PSA: >4.0 ng/mL
• Free PSA ratio: <15%
Interpretation:
Higher suspicion of prostate cancer. Further urology investigation advised.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
Usually from age 40–45, especially with family history.
No fasting is required.
Yes, heavy cycling or ejaculation before the test may raise PSA temporarily.
No, many benign conditions can raise PSA.
It helps differentiate benign prostate issues from cancer risk.
Yes, trends over time are important.
Yes, prostatitis can increase PSA levels.
No, it is a simple blood test.
If PSA is persistently raised or ratio is low.
Yes, weight, diet, and inflammation can influence levels.
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