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Prostate PSA Profile

Cancer and Tumour Markers
89.00

Private Prostate PSA Profile in London for £89, assessing three PSA markers to support more detailed prostate risk assessment.

Turnaround time

1-2 business days

Biomarkers count

3

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Same-Day Appointments
UKAS Accredited Labs

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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Overview of the Prostate PSA Profile

The Prostate PSA Profile measures Total PSA, Free PSA and the Free-to-Total PSA Ratio to provide more information than Total PSA alone.

The test contains 3 biomarkers.

PSA is a protein produced by prostate tissue. Small amounts normally circulate in blood.

PSA can increase because of benign prostate enlargement, prostatitis, urinary infection, recent prostate manipulation and prostate cancer.

This means an elevated Total PSA is not a diagnosis of prostate cancer.

Free PSA measures the fraction circulating without being bound to proteins.

In selected men with an intermediate Total PSA concentration, the proportion that is free can provide additional risk information.

A lower Free-to-Total PSA Ratio can be associated with a greater probability of prostate cancer, whereas higher proportions are more commonly seen with benign prostate enlargement. There is substantial overlap, however, and no ratio can confirm or exclude cancer.

PSA should therefore be interpreted alongside age, symptoms, family history, previous PSA trend, medication and, where clinically appropriate, prostate examination or MRI.

What Does the Prostate PSA Profile Check?

This test measures 3 biomarkers.

Prostate Markers
Total Prostate Specific Antigen

Measures the total concentration of PSA circulating in the blood.

Free Prostate Specific Antigen

Measures the unbound fraction of circulating PSA.

Free : Total PSA Ratio

Calculates the proportion of Total PSA that is present in the free form and can provide additional risk information in selected clinical circumstances.

Who May Benefit From the Prostate PSA Profile?

This profile may be useful when a man wants more detailed PSA assessment than Total PSA alone, particularly where a previous result is borderline, elevated or requires follow-up.

Men with a previous borderline Total PSA - Free PSA and the ratio can add information to the overall risk assessment.

Men with a persistently raised PSA result - Repeat testing can establish the trend and provide additional context.

Men with a strong family history of prostate cancer - Familial risk can make earlier or closer assessment appropriate.

Men with lower urinary tract symptoms - Prostate enlargement and inflammation can affect both urinary symptoms and PSA.

Men undergoing urological follow-up - A specialist may request Free PSA or the ratio as part of ongoing assessment.

Men considering PSA testing after an informed discussion - Understanding the benefits and limitations of PSA testing is important.

Men monitoring a previous prostate abnormality - Serial PSA measurements can provide useful information about change over time.

How to Prepare

PSA can be temporarily influenced by several activities and prostate conditions, so appropriate preparation helps reduce avoidable variation.
Fasting
Fasting is not required.
Hydration
Drink water normally before your appointment.
Ejaculation
Avoid ejaculation for approximately 48 hours before testing where possible because it can temporarily increase PSA.
Cycling
Avoid prolonged or strenuous cycling immediately before testing because pressure on the prostate may affect PSA.
Urinary infection
If you have an active urinary infection or prostatitis, discuss the appropriate timing of PSA testing with a clinician.
Prostate procedures
Tell the clinician about recent prostate biopsy, catheterisation, cystoscopy or other prostate or urinary procedures.
Medication
Tell the clinician if you take Finasteride or Dutasteride because these medicines can substantially lower PSA concentrations.
Previous results
Keep previous Total PSA, Free PSA and prostate imaging results where available.

Do not stop prescribed prostate medication simply to obtain a different PSA result.

Recent infection or prostate manipulation can significantly influence PSA and may make postponing routine testing more appropriate.

Symptoms and Reasons to Consider the Prostate PSA Profile Test

Prostate conditions can cause urinary symptoms, although early prostate cancer may produce no symptoms at all.

Difficulty starting urination - Urinary obstruction can occur with benign prostate enlargement and other prostate conditions.

A weak urinary stream - Reduced flow may result from prostate enlargement.

Needing to urinate more frequently - Lower urinary tract symptoms become more common as the prostate enlarges.

Frequent urination at night - Nocturia can occur with benign prostate enlargement and other urinary conditions.

Feeling that the bladder has not emptied fully - This can occur when urinary flow is obstructed.

A previous elevated PSA - More detailed PSA assessment may provide additional context.

No symptoms but a strong family history of prostate cancer - Prostate cancer can be asymptomatic in its earlier stages.

A persistently changing PSA trend - Changes over time may warrant further assessment even when symptoms are absent.

Urinary symptoms are more commonly caused by benign prostate enlargement than by prostate cancer.

Inability to pass urine, significant blood in the urine, severe urinary pain or fever with suspected prostatitis requires prompt clinical assessment.

How to Book Your Prostate PSA Profile

The Prostate PSA Profile can be booked privately through London Blood Tests for more detailed biochemical prostate assessment.

1
Choose the Prostate PSA Profile

Select the three-marker prostate profile online.

2
Select your sample collection option

Choose an in-clinic blood draw or professional home or hotel phlebotomy depending on location and availability.

3
Attend your appointment

A trained healthcare professional collects the required venous blood sample.

4
Laboratory analysis

Total PSA and Free PSA are measured and the Free : Total PSA Ratio is calculated.

5
Receive your results securely

Your authorised prostate report is delivered securely and can be reviewed with a GP or urologist where appropriate.

When Will I Receive My Results?

The expected turnaround time for the Atypical Pneumonia Screen is approximately 7 business days.

Results are sent securely by email once specialist laboratory analysis and authorisation are complete. Turnaround generally begins when the laboratory receives your blood sample rather than necessarily from the time it is collected.

Specialist serology can occasionally require repeat analysis, confirmatory review or additional laboratory processing, which may extend the expected turnaround.

Understanding Your Results

The three results should be interpreted together, alongside age, symptoms and previous PSA history.

A lower Total PSA is generally reassuring but does not completely exclude prostate cancer.

A raised Total PSA can occur with cancer but also with benign prostate enlargement, prostatitis, infection and recent prostate manipulation.

Free PSA and the Free : Total PSA Ratio can provide additional information where Total PSA falls into an intermediate range.

A lower proportion of Free PSA may be associated with a greater probability of prostate malignancy, while a higher percentage is more commonly associated with benign prostate disease.

There is no single PSA concentration or Free PSA ratio that definitively diagnoses cancer.

Persistently abnormal results can lead to repeat PSA testing, GP or urology review, prostate examination or MRI depending on the clinical circumstances.

Why Book With London Blood Tests?

This profile provides more detailed PSA information than Total PSA alone and can be particularly useful when previous prostate results need further context.

Three PSA measures - Total PSA, Free PSA and the Free : Total PSA Ratio are assessed together.

More detailed than Total PSA alone - The free fraction can refine interpretation of selected borderline results.

Useful for serial monitoring - Changes over time can be compared with previous PSA measurements.

Relevant to family risk - Testing may be appropriate where close relatives have had prostate cancer.

Private prostate testing in London - Professional blood collection is available privately.

Clinic and home collection options - Collection can be arranged according to location and availability.

Fast results - Results are expected approximately 1–2 business days after laboratory receipt.

Clear pricing - The Prostate PSA Profile costs £89.

Private Prostate PSA Profile Blood Test in London

London Blood Tests provides private Prostate PSA Profile testing in London for men seeking more detailed prostate-marker assessment.

The test costs £89 and measures 3 biomarkers: Total Prostate Specific Antigen, Free Prostate Specific Antigen and Free : Total PSA Ratio.

Results are expected approximately 1–2 business days after laboratory receipt.

An abnormal PSA profile should be interpreted in the wider clinical context and may require repeat testing, MRI or specialist urological review.

Frequently Asked Questions

No. PSA can also rise because of benign prostate enlargement, prostatitis, urinary infection and recent prostate manipulation.

Free PSA is the portion of Prostate Specific Antigen circulating in the blood that is not bound to other proteins.

The ratio can provide additional risk information when Total PSA is borderline or moderately elevated.

Yes. PSA testing does not detect every prostate cancer.

Yes. Ejaculation can temporarily increase PSA, so avoiding it for around 48 hours beforehand is commonly recommended.

Prolonged or intense cycling can place pressure on the prostate and may temporarily influence PSA in some men.

Yes. Both medicines can substantially reduce PSA levels and must be considered during interpretation.

Yes. Prostate inflammation can significantly increase PSA.

Depending on the degree of elevation and the clinical circumstances, repeat testing before further investigation may be appropriate.

Results are expected approximately 1–2 business days after laboratory receipt.
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