Protein/Creatinine Ratio (Urine)
The urine protein/creatinine ratio assesses protein loss in urine. It helps detect kidney damage and monitor renal health.
Turnaround time
Results available 4 hours after arrival in lab. Doctor's report sent the day after results available (if required)
Biomarkers count
1
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Details about Protein/Creatinine Ratio (Urine)
What is the Protein/Creatinine Ratio (Urine) test?
The Protein/Creatinine Ratio (Urine) test measures the amount of protein in urine relative to creatinine concentration. This ratio provides an accurate estimate of daily protein loss without the need for a 24-hour urine collection.
Healthy kidneys prevent significant amounts of protein from leaking into urine. When kidney filtration is impaired, protein loss increases, making this test a key marker of kidney damage.
It is widely used to assess and monitor chronic kidney disease, diabetic nephropathy, hypertension-related kidney damage, and other renal conditions.
Why do I need a test for Protein/Creatinine Ratio?
Protein loss in urine is often one of the earliest signs of kidney disease and may occur before symptoms develop. Measuring the protein/creatinine ratio helps detect kidney damage early and assess disease progression.
This test is especially useful for people with diabetes, high blood pressure, autoimmune disease, or abnormal urine findings.
You may benefit from this test if you experience or have:
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Diabetes or prediabetes
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High blood pressure
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Known kidney disease
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Foamy or cloudy urine
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Swelling of ankles, legs, or face
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Abnormal urine dipstick results
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Autoimmune or inflammatory disease
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Monitoring of kidney function over time
Benefits of the Protein/Creatinine Ratio test
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Early detection of kidney damage
Identifies abnormal protein loss before symptoms appear. -
Convenient alternative to 24-hour urine testing
Requires only a single urine sample. -
Monitors chronic kidney disease progression
Tracks changes in protein leakage over time. -
Assesses diabetic kidney involvement
Important for diabetes-related renal monitoring. -
Supports blood pressure-related kidney assessment
Detects damage linked to hypertension. -
Useful in autoimmune kidney conditions
Helps monitor glomerular disease activity. -
Guides treatment effectiveness
Protein reduction often reflects treatment response. -
Non-invasive renal health assessment
Simple urine-based testing.
Step-by-step – how we offer Protein/Creatinine Ratio testing
Clinic-based testing (UK-wide)
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Choose your nearest UK clinic
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Attend your appointment
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Provide a urine sample following instructions
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Sample is sent to the laboratory for analysis
At-home or hotel testing (+£60)
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A clinician or phlebotomist visits your home or hotel
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Urine sample collected at your location
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No clinic visit or travel required
Both services are available UK-wide.
Your Protein/Creatinine Ratio results explained
Normal protein/creatinine ratio
Normal results indicate minimal protein loss and healthy kidney filtration. This suggests preserved kidney function at the time of testing.
UK reference range:
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Normal: <15 mg/mmol
Moderately increased protein loss
Moderately raised ratios suggest early kidney damage or increased filtration pressure. This is often seen in early diabetic or hypertensive kidney disease.
Monitoring and risk factor management are usually advised.
UK reference range:
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Moderate: 15–50 mg/mmol
High protein/creatinine ratio
High ratios indicate significant protein loss and established kidney damage. This may reflect glomerular disease or advanced chronic kidney disease.
Further renal evaluation is often required.
UK reference range:
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High: >50 mg/mmol
How It Works
Simple steps to get your results
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
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WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.