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Skin (Pemphigus/Pemphigoid) Autoantibodies
85.00
The Pemphigus/Pemphigoid Autoantibodies test detects immune antibodies linked to autoimmune blistering skin diseases. It supports accurate diagnosis and specialist referral using advanced laboratory methods.
Turnaround time
Results available 2 days after arrival in lab. Doctor's report sent the day after results available (if required)
Biomarkers count
1
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Skin (Pemphigus/Pemphigoid) Autoantibodies
What is the Skin (Pemphigus/Pemphigoid) Autoantibodies test?
This is a blood test that detects autoantibodies targeting structural proteins within the skin, which are responsible for maintaining skin integrity. In autoimmune blistering disorders, the immune system mistakenly attacks these proteins, leading to blistering and skin fragility.
The test typically identifies antibodies associated with pemphigus and pemphigoid, two distinct but related autoimmune skin conditions. Detection is performed using specialised immunological techniques, often including immunofluorescence or antigen-specific assays.
Why do I need a Pemphigus/Pemphigoid autoantibodies test?
Autoimmune blistering skin diseases can be difficult to diagnose based on appearance alone, as symptoms may mimic infections, allergic reactions, or other inflammatory skin conditions. Identifying disease-specific autoantibodies helps confirm an autoimmune cause and guides appropriate management.
You may need this test if you have:
- Persistent or recurrent skin blisters
- Fragile skin that tears or erodes easily
- Painful sores on the skin or mucous membranes
- Chronic, unexplained rashes not responding to treatment
- Suspected pemphigus or bullous pemphigoid
- Symptoms requiring dermatology or immunology assessment
Benefits of the Pemphigus/Pemphigoid Autoantibodies test
- Supports definitive diagnosis
Identifies autoimmune causes of blistering skin disease. - Differentiates similar conditions
Helps distinguish pemphigus from pemphigoid. - Non-invasive blood test
No skin biopsy required for initial screening. - Guides specialist referral
Supports timely dermatology input. - High diagnostic specificity
Uses advanced immunological testing. - Useful when symptoms are unclear
Adds objective evidence to clinical assessment. - May help monitor disease activity
Antibody levels can correlate with severity. - Improves treatment planning
Supports appropriate long-term management decisions.
Step-by-step – How we offer this test
Option 1: Clinic-based blood test (UK-wide)
- Choose your nearest UK clinic
- Attend your appointment
- Blood sample taken by a clinician
- Sample analysed for pemphigus/pemphigoid autoantibodies
Option 2: Home or hotel visit (+£60, UK-wide)
- Qualified phlebotomist attends your location
- Blood sample taken at home or hotel
- No need to travel
- Same laboratory analysis and reporting
Your results explained
Negative autoantibody result
No detectable pemphigus or pemphigoid autoantibodies.
Typical UK interpretation:
- No significant autoantibody activity detected
This reduces the likelihood of autoimmune blistering disease but does not fully exclude it.
Positive autoantibody result
Autoantibodies associated with pemphigus or pemphigoid are detected.
Typical UK interpretation:
- Detectable disease-associated autoantibodies
This supports a diagnosis of autoimmune blistering skin disease and usually warrants specialist review.
High autoantibody levels
High titres of disease-specific autoantibodies.
Typical UK interpretation:
- Elevated autoantibody levels
Often associated with active or more extensive disease.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
It strongly supports diagnosis but is interpreted alongside symptoms and clinical findings.
They affect different skin layers and involve different target proteins.
No. This is a blood test; biopsies may still be required for confirmation.
No. Fasting is not required.
Immunosuppressive treatment may lower antibody levels.
Yes, in some cases antibody levels correlate with disease severity.
It may be used under specialist guidance.
Results are usually available within several working days.
Referral to a dermatologist or immunologist is usually advised.
Yes. Both clinic-based and home testing are available across the UK.
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