Syphilis (IgG/IgM)
Private Syphilis IgG/IgM testing in London for £68, measuring one Treponema pallidum antibody marker with results expected in around 2 days.
Turnaround time
2 business days
Biomarkers count
1
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Overview of the Syphilis (IgG/IgM) Test
The Syphilis (IgG/IgM) blood test detects antibodies produced against Treponema pallidum, the bacterium responsible for syphilis.
The test assesses 1 specialist infection marker: Syphilis IgG/IgM.
Syphilis is a sexually transmitted bacterial infection that can progress through several stages if it is not treated.
Primary syphilis can cause a painless ulcer known as a chancre.
The lesion may disappear without treatment, even though infection remains present.
Secondary syphilis can produce a widespread rash, lymph-node swelling and other systemic symptoms.
After these early stages, infection can become latent and produce no symptoms for a prolonged period.
Serological testing is therefore central to syphilis assessment because infection can be present even when there is no visible lesion.
IgM antibodies can appear relatively early after infection, while IgG antibodies develop and can remain detectable for many years.
However, the distinction is not sufficiently precise to determine the exact timing or activity of infection from IgG and IgM alone.
A reactive syphilis antibody result commonly requires confirmatory and activity testing, such as TPPA together with a non-treponemal test such as RPR.
Treponemal antibodies can remain positive after successful treatment.
This means a person with previously treated syphilis may continue to have reactive antibody tests.
Testing too soon after a new exposure can also produce a negative result because antibodies have not yet developed.
The date of possible exposure, symptoms and previous syphilis history are therefore essential for interpretation.
What Does the Syphilis (IgG/IgM) Test Check?
The test detects IgG and IgM antibodies associated with exposure to Treponema pallidum. This test measures 1 specialist biomarker.
Syphilis IgG/IgM
Detects antibodies produced against Treponema pallidum, supporting syphilis screening and assessment across different stages of infection.
Who May Benefit From the Syphilis (IgG/IgM) Test?
Syphilis antibody testing can be useful for routine screening, after potential sexual exposure or where compatible symptoms are present.
People following unprotected sexual contact - Syphilis can be transmitted even when the other person has no recognised symptoms.
People with a new sexual partner - Routine STI screening can provide useful information where exposure status is uncertain.
People with a partner diagnosed with syphilis - Prompt sexual-health assessment and testing are important.
People with a painless genital, anal or oral ulcer - Primary syphilis can present with a chancre.
People with an unexplained widespread rash - Secondary syphilis can produce a characteristic rash, including the palms or soles.
Pregnant people requiring syphilis assessment - Untreated maternal syphilis can affect pregnancy and the developing baby.
People with a previous syphilis infection and a new exposure - Previous infection does not provide reliable protection against reinfection.
People seeking confidential routine sexual-health screening - Syphilis can remain asymptomatic.
How to Prepare
Do not assume one early negative result excludes syphilis after a recent exposure.
Repeat testing or direct PCR from a suitable lesion may be appropriate depending on timing and symptoms.
Symptoms and Reasons to Consider the Syphilis (IgG/IgM) Test
Syphilis has several clinical stages and can also remain asymptomatic.
A painless genital, anal or oral ulcer - A chancre is a recognised feature of primary syphilis.
A rash involving the palms or soles - Secondary syphilis can produce a widespread characteristic rash.
Unexplained swollen lymph nodes - Lymphadenopathy can occur during early infection.
Flu-like symptoms following relevant sexual exposure - Secondary infection can produce systemic symptoms.
A sexual partner diagnosed with syphilis - Exposure can occur before obvious symptoms develop.
Pregnancy with possible syphilis exposure - Prompt assessment is important because untreated infection can be transmitted to the fetus.
Neurological, visual or hearing symptoms with possible syphilis - Later or specialised forms of infection require urgent clinical assessment.
No symptoms following a potential exposure - Absence of symptoms does not exclude syphilis.
Very early infection can occur before antibodies become detectable.
A negative result obtained shortly after exposure may therefore need to be repeated.
Neurological, visual or hearing symptoms in somebody with possible syphilis require prompt specialist assessment.
How to Book Your Syphilis (IgG/IgM) Test
The Syphilis IgG/IgM test can be booked privately for confidential syphilis antibody screening.
Choose the Syphilis (IgG/IgM)
Select the individual Syphilis IgG/IgM blood test online.
Select your sample collection option
Choose an in-clinic blood draw or professional home or hotel phlebotomy where suitable.
Attend your appointment
A trained healthcare professional collects the required venous blood sample confidentially.
Laboratory analysis
Your serum undergoes measurement of Syphilis IgG/IgM antibodies.
Receive your results securely
Your authorised result is delivered securely and reactive results can be followed by appropriate confirmatory testing.
When Will I Receive My Results?
The current live London Blood Tests page lists a turnaround of approximately 2 days after laboratory receipt for Syphilis (IgG/IgM).
The sample undergoes serological antibody analysis, laboratory quality-control procedures and result authorisation.
Turnaround begins when the specimen reaches the laboratory rather than necessarily from the exact time of collection.
A reactive screening result can require confirmatory TPPA, RPR or other serological testing and this can extend the overall investigation.
Understanding Your Results
A negative result means syphilis antibodies were not detected at the time of testing.
Where sufficient time has passed since exposure, this is reassuring.
Testing during the early antibody window period can produce a negative result despite infection.
A reactive result indicates antibodies associated with Treponema pallidum have been detected.
The result does not necessarily mean infection is newly acquired or currently active.
Treponemal antibodies can persist after previous successfully treated infection.
Additional testing is therefore usually required to establish the clinical meaning.
TPPA can confirm specific Treponema pallidum antibody reactivity.
RPR or another non-treponemal test can provide information about current disease activity and can be followed after treatment.
Previous treatment history is particularly important because it changes how a persistent antibody result should be interpreted.
Why Book With London Blood Tests?
London Blood Tests provides private and confidential syphilis antibody testing in London.
Detects syphilis-related antibodies - The test measures IgG and IgM associated with Treponema pallidum exposure.
Suitable for asymptomatic screening - Syphilis can remain clinically silent.
Useful across different stages of infection - Antibody testing remains relevant after an early lesion has disappeared.
Can be followed by confirmatory testing - TPPA and RPR can provide additional diagnostic information.
Relevant during pregnancy - Prompt identification and treatment of maternal syphilis are clinically important.
Rapid laboratory turnaround - Results are expected approximately 2 days after laboratory receipt.
Professional confidential collection - Clinic and suitable home or hotel blood collection are available.
Clear pricing - The Syphilis (IgG/IgM) test costs £68.
Private Syphilis (IgG/IgM) Blood Test in London
London Blood Tests provides private Syphilis IgG/IgM testing for people requiring confidential screening for Treponema pallidum infection.
The test costs £68 and assesses 1 specialist antibody marker.
Results are expected approximately 2 days after laboratory receipt.
Reactive antibody results require interpretation with previous infection history and appropriate confirmatory testing.