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Thyroid Antibodies (incl. Thyroglobulin + Thyroid Peroxidase Antibodies)
119.00
This blood test measures thyroid antibodies linked to autoimmune thyroid conditions. It helps identify immune-related causes of thyroid dysfunction, even when hormone levels appear normal.
Turnaround time
2 days
Biomarkers count
1
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Thyroid Antibodies (incl. Thyroglobulin + Thyroid Peroxidase Antibodies)
What is the Thyroid Antibodies Test?
The Thyroid Antibodies test measures immune antibodies that target thyroid tissue, specifically Thyroid Peroxidase Antibodies (TPOAb) and Thyroglobulin Antibodies (TgAb). These antibodies indicate whether the immune system is attacking the thyroid gland.
TPO antibodies interfere with thyroid hormone production, while thyroglobulin antibodies target thyroglobulin, a protein essential for hormone synthesis. Their presence suggests autoimmune thyroid disease rather than a purely hormonal imbalance.
This test is commonly used to investigate suspected autoimmune thyroid conditions, unexplained thyroid symptoms, or abnormal thyroid hormone results.
Why do I need a Thyroid Antibodies test?
Autoimmune thyroid disease is one of the most common causes of thyroid dysfunction and may be present even when standard thyroid hormone tests are borderline or normal.
You may need this test if you experience:
- Persistent fatigue or low energy
- Weight gain or unexplained weight loss
- Cold or heat intolerance
- Hair thinning or hair loss
- Anxiety, low mood, or brain fog
- Palpitations or tremors
- Neck discomfort or thyroid swelling
- Family history of autoimmune disease
- Abnormal or fluctuating thyroid hormone levels
Identifying antibodies helps distinguish autoimmune thyroid disease from other causes and supports long-term monitoring decisions.
Benefits of the test
- Detects autoimmune thyroid disease
Identifies immune-mediated causes of thyroid dysfunction. - Explains symptoms with normal hormones
Antibodies may be present before hormone changes occur. - Supports early diagnosis
Detects disease in early or subclinical stages. - Differentiates thyroid conditions
Helps distinguish autoimmune from non-autoimmune causes. - Useful for long-term monitoring
Antibody trends can reflect disease activity. - Relevant for fertility and pregnancy planning
Thyroid autoimmunity can affect reproductive health. - Supports treatment decisions
Provides context for thyroid hormone management. - Simple blood-based testing
Requires only a single blood sample.
Step-by-step: How we offer testing
Clinic-based testing (UK-wide)
- Choose your nearest UK clinic
- Attend your appointment
- A clinician draws a blood sample
- Sample is sent to the laboratory
- Results are issued once analysis is complete
Home or hotel visit (+£60, UK-wide)
- Book a mobile phlebotomist
- Blood sample taken at your home or hotel
- No need to attend a clinic
- Sample securely transported to the laboratory
Your results explained
Negative antibodies
- TPO and thyroglobulin antibodies not detected
- UK standard: Negative
- Suggests thyroid dysfunction is unlikely to be autoimmune
Mild to moderately elevated antibodies
- Antibodies above reference range
- UK standard (typical):
- TPOAb: >35 IU/mL
- TgAb: >115 IU/mL
- Suggests autoimmune thyroid activity
High antibody levels
- Markedly elevated antibody titres
- UK standard: Significantly above reference range
- Commonly seen in autoimmune thyroid conditions such as Hashimoto’s or Graves’-related autoimmunity
Antibody levels should always be interpreted alongside thyroid hormone tests and clinical symptoms.
How It Works
Simple steps to get your results
1
Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
They indicate immune system activity against the thyroid gland.
Yes, autoimmune thyroid disease can exist before hormone changes occur.
They may persist long-term but can fluctuate over time.
Not always; some people remain asymptomatic initially.
Yes, especially thyroid peroxidase antibodies.
Yes, thyroid autoimmunity may impact reproductive outcomes.
Autoimmune thyroid disease often runs in families.
Stress may influence immune activity and disease expression.
Monitoring may be useful in certain clinical contexts.
It indicates autoimmune involvement of the thyroid and supports further endocrine evaluation.
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