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Thyroid Receptor Antibodies
214.00
This blood test measures thyroid receptor antibodies linked to autoimmune thyroid disease. It is most commonly used to diagnose and monitor Graves’ disease.
Turnaround time
5 days
Biomarkers count
1
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Thyroid Receptor Antibodies
What is the Thyroid Receptor Antibodies test?
The Thyroid Receptor Antibodies (TRAb) test measures antibodies that target the thyroid-stimulating hormone (TSH) receptor on thyroid cells. These antibodies interfere with normal thyroid regulation by stimulating or blocking the receptor.
In most cases, TRAb stimulate the TSH receptor, causing excessive thyroid hormone production. This mechanism is central to Graves’ disease, the most common cause of hyperthyroidism.
The test helps confirm autoimmune hyperthyroidism and assess disease activity over time.
Why do I need a Thyroid Receptor Antibodies test?
Hyperthyroidism can have several causes, and identifying whether it is autoimmune is essential for correct diagnosis and management.
You may need this test if you experience:
- Palpitations or rapid heartbeat
- Anxiety or nervousness
- Weight loss despite normal appetite
- Heat intolerance or excessive sweating
- Tremor
- Eye symptoms (bulging eyes, irritation)
- Suppressed TSH with raised Free T4 or Free T3
- Suspected or known Graves’ disease
- Monitoring response to treatment
This test helps distinguish Graves’ disease from other causes of overactive thyroid.
Benefits of the test
- Confirms Graves’ disease
Key marker of autoimmune hyperthyroidism. - Differentiates causes of hyperthyroidism
Helps rule out non-autoimmune thyroid conditions. - Useful when hormone results are unclear
Adds immune context to thyroid function tests. - Supports treatment monitoring
Antibody levels often reflect disease activity. - Relevant for eye-related thyroid disease
Often elevated in Graves’ ophthalmopathy. - Improves diagnostic confidence
Reduces uncertainty in hyperthyroid cases. - Simple blood-based test
Requires only a single blood sample. - Useful in pregnancy-related assessment
Helps assess autoimmune thyroid risk when indicated.
Step-by-step: How we offer testing
Clinic-based testing (UK-wide)
- Choose your nearest UK clinic
- Attend your appointment
- A clinician draws a blood sample
- Sample is sent to the laboratory
- Results are issued once analysis is complete
Home or hotel visit (+£60, UK-wide)
- Book a mobile phlebotomist
- Blood sample taken at your home or hotel
- No need to attend a clinic
- Sample securely transported to the laboratory
Your results explained
Negative TRAb
- Thyroid receptor antibodies not detected
- UK standard: Negative
- Autoimmune hyperthyroidism unlikely
Mildly elevated TRAb
- Antibodies above reference range
- UK standard (typical): >1.8 IU/L
- Suggests autoimmune thyroid activity
High TRAb levels
- Markedly elevated antibodies
- UK standard: Significantly above 1.8 IU/L
- Strongly supportive of active Graves’ disease
TRAb levels should always be interpreted alongside thyroid hormone results and symptoms.
How It Works
Simple steps to get your results
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Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
2
Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
3
Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
Thyroid Receptor Antibodies.
Yes, it is the most specific blood marker for Graves’ disease.
Yes, especially early or treated disease.
Yes, falling levels often indicate reduced disease activity.
Yes, they are linked to Graves’ eye disease.
Yes, TPO antibodies indicate autoimmunity but not hyperthyroid stimulation.
Yes, which is why monitoring may be important in pregnancy.
It reduces likelihood but does not exclude all cases.
Yes, levels can change with treatment or disease activity.
It indicates autoimmune stimulation of the thyroid and supports a diagnosis of Graves’ disease.
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