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Total Protein

Organ Function & Health
48.00

Private Total Protein testing in London for £48, measuring one blood protein marker with results expected in around 1–2 days.

Turnaround time

1-2 business days

Biomarkers count

1

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Same-Day Appointments
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Overview of the Total Protein Test

The Total Protein blood test measures the combined concentration of the major proteins circulating in serum, principally Albumin and Globulins.

The test assesses 1 biochemical biomarker: Total Protein.

Blood proteins perform a wide range of functions.

Albumin is produced mainly by the liver and helps maintain oncotic pressure, transport hormones and carry numerous substances through the bloodstream.

Globulins include antibodies and many transport and immune proteins.

Total Protein therefore provides a broad measure of the overall amount of protein circulating in blood.

A low result can occur when protein production is reduced, protein is lost excessively or nutritional intake and absorption are inadequate.

Examples include significant liver disease, kidney protein loss, gastrointestinal protein loss and severe malnutrition.

A high Total Protein result can occur with dehydration, which concentrates blood proteins.

It can also occur when Immunoglobulins are increased because of chronic inflammation, infection or plasma-cell disorders.

Because the test combines different protein groups, an abnormal Total Protein result does not identify which protein is responsible.

Albumin, calculated Globulin and the Albumin-to-Globulin ratio can provide more detail.

Where an abnormal globulin pattern is suspected, Protein Electrophoresis can separate serum proteins into different fractions and detect monoclonal protein bands.

Total Protein is therefore most useful as part of a broader liver, kidney, nutritional or immunological assessment.

What Does the Total Protein Test Check?

The test measures the combined amount of Albumin and Globulin proteins in blood. This test measures 1 biomarker.

Blood Protein Balance
Total Protein

Measures the combined concentration of circulating Albumin and Globulins, providing information relevant to liver function, nutritional status, immune proteins and protein loss.

Who May Benefit From the Total Protein Test?

Total Protein testing can be useful as part of liver, kidney, nutritional and immune-system assessment.

People with abnormal liver-function results - Liver disease can alter protein production.

People with suspected nutritional deficiency or malabsorption - Severe protein deficiency can reduce circulating protein.

People with kidney disease or protein in the urine - Renal protein loss can lower blood protein concentrations.

People with unexplained swelling or oedema - Low Albumin and altered protein balance can contribute to fluid retention.

People with unexpectedly high Globulin levels - Total Protein provides context before more detailed protein studies.

People with recurrent or chronic inflammatory conditions - Increased Immunoglobulins can raise Total Protein.

People with an unexplained high Total Protein result - Protein Electrophoresis can sometimes be required.

People monitoring liver, kidney or nutritional health - Total Protein is commonly included in broader biochemical profiles.

How to Prepare

Fasting
Fasting is not usually required.
Hydration
Maintain normal hydration because dehydration can artificially increase protein concentration.
Medication
Continue prescribed medication unless your clinician advises otherwise.
Supplements
Record protein supplements or nutritional products where relevant.
Liver disease
Provide information about known liver conditions.
Kidney disease
Tell the clinician about known kidney disease or previous urinary protein abnormalities.
Recent illness
Significant infection or inflammation can alter Globulin concentrations.
Previous results
Keep previous Total Protein, Albumin, Globulin and Protein Electrophoresis results where available.

Avoid arriving significantly dehydrated because concentration of the blood can influence Total Protein.

The result should be considered alongside Albumin and Globulin wherever possible.

Symptoms and Reasons to Consider the Total Protein Test

Abnormal Total Protein usually produces no specific symptoms of its own.

Persistent swelling or fluid retention - Significant protein abnormalities can affect fluid distribution.

Unexplained weight loss or poor nutrition - Reduced intake or malabsorption can alter protein status.

Chronic liver disease - Protein synthesis can be affected.

Protein detected in urine - Kidney protein loss can reduce serum protein concentrations.

Recurrent infections or immune-system concerns - Globulin abnormalities can influence Total Protein.

Unexpectedly high Globulin or Total Protein - Further protein analysis can be required.

Persistent fatigue with abnormal liver or kidney results - Total Protein can contribute to the broader investigation.

Total Protein is a non-specific marker and cannot diagnose liver disease, malnutrition, immune disease or a plasma-cell disorder by itself.

Marked swelling, jaundice, severe illness or significant kidney symptoms require appropriate clinical assessment.

How to Book Your Total Protein Test

The Total Protein test can be booked privately for assessment of circulating protein balance.

1
Choose the Total Protein

Select the individual Total Protein blood test online.

2
Select your sample collection option

Choose an in-clinic blood draw or professional home or hotel phlebotomy where suitable.

3
Attend your appointment

A trained healthcare professional collects the required venous blood sample.

4
Laboratory analysis

Your serum undergoes measurement of Total Protein.

5
Receive your results securely

Your authorised result is delivered securely and can be interpreted alongside Albumin, Globulin and other liver or kidney markers.

When Will I Receive My Results?

The current London Blood Tests turnaround for Total Protein is approximately 1–2 days after laboratory receipt.

Total Protein is a routine biochemical assay and can often be processed rapidly.

The result undergoes laboratory quality control and authorisation before release.

Understanding Your Results

A low Total Protein result means the combined Albumin and Globulin concentration is below the laboratory range.

Possible causes include reduced protein synthesis, kidney or gastrointestinal protein loss and severe nutritional deficiency.

A high Total Protein result can occur because of dehydration or increased Globulin production.

Persistent high Total Protein with increased Globulin can lead to further testing such as Protein Electrophoresis.

A result within range does not guarantee that every individual protein fraction is normal.

For example, Albumin could be low while Globulins are increased, producing a Total Protein result that still falls within range.

This is why Total Protein is often interpreted alongside Albumin and calculated Globulin.

Why Book With London Blood Tests?

London Blood Tests provides private Total Protein testing for general biochemical, liver and nutritional assessment.

Measures overall circulating protein - The test combines Albumin and Globulins.

Relevant to liver assessment - Albumin production depends substantially on liver function.

Relevant to kidney protein loss - Renal disease can reduce circulating protein.

Useful in nutritional assessment - Severe malnutrition or malabsorption can affect protein concentrations.

Can identify the need for further protein studies - Persistent elevation can prompt Protein Electrophoresis.

Rapid laboratory turnaround - Results are expected approximately 1–2 days after laboratory receipt.

Professional blood collection - Clinic and suitable home or hotel appointments are available.

Clear pricing - The Total Protein test costs £48.

Private Total Protein Blood Test in London

London Blood Tests provides private Total Protein testing for people requiring assessment of circulating protein balance.

The test costs £48 and measures 1 biochemical biomarker.

Results are expected approximately 1–2 days after laboratory receipt.

Abnormal Total Protein should usually be interpreted alongside Albumin, Globulin, liver function and kidney results.

Frequently Asked Questions

It measures the combined amount of Albumin and Globulin proteins circulating in blood.

Causes include reduced liver protein production, kidney or gastrointestinal protein loss and severe nutritional deficiency.

Dehydration and increased Immunoglobulin production are common possibilities.

No. Albumin is one component of Total Protein.

Yes. Reduced plasma water can concentrate blood proteins.

It separates different protein fractions and can identify abnormal monoclonal protein patterns.

Usually not.

Yes. Significant urinary protein loss can reduce circulating concentrations.

Chronic inflammation can increase Globulin proteins and raise Total Protein.

Results are expected approximately 1–2 days after laboratory receipt.
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