1,25-dihydroxyvitamin D (calcitriol)
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Urine Steroid Screen
1090.00
The Urine Steroid Screen analyses steroid hormone metabolites excreted in urine. It helps assess adrenal function, steroid metabolism, and hormonal imbalance.
Turnaround time
Results available 2 weeks after arrival in lab. Doctor's report sent the day after results available (if required)
Biomarkers count
1
Same-Day Appointments
UKAS Accredited Labs
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Under 18? Patients under 18 can only be seen at GB Medlabs and Clinilabs, Monday to Friday only.
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Details about Urine Steroid Screen
What is the Urine Steroid Screen?
The Urine Steroid Screen is a laboratory test that measures a range of steroid hormone metabolites in urine. Steroid hormones are produced mainly by the adrenal glands and include cortisol, cortisone, and androgen-related hormones.
Unlike single blood hormone measurements, urine testing reflects hormone production and breakdown over time, offering insight into how steroids are metabolised rather than just their circulating levels. This makes it particularly useful for complex endocrine assessment.
The test is commonly used in endocrinology to investigate adrenal disorders and unexplained hormonal symptoms.
Why do I need a Urine Steroid Screen?
Steroid hormone imbalance can cause wide-ranging symptoms and may not be fully explained by standard blood tests alone.
You may need this test if you experience:
- Unexplained fatigue or weakness
- Symptoms of cortisol excess or deficiency
- Weight changes without clear cause
- Blood pressure abnormalities
- Hormonal imbalance with unclear origin
- Suspected adrenal dysfunction
- Abnormal cortisol blood test results
- Investigation of steroid metabolism disorders
The test helps determine whether symptoms are related to abnormal steroid production or metabolism.
Benefits of the test
- Assesses adrenal steroid production
Provides insight into cortisol and androgen metabolism. - Reflects hormone output over time
Less affected by short-term fluctuations. - Useful in complex endocrine cases
Helps when blood tests are inconclusive. - Supports adrenal function assessment
Identifies patterns of excess or deficiency. - Non-invasive testing
Uses a urine sample rather than blood. - Complements blood hormone tests
Adds metabolic context. - Widely used in specialist endocrinology
Standard test in adrenal investigations. - Improves diagnostic clarity
Helps guide further endocrine evaluation.
Step-by-step: How we offer testing
Clinic-based testing (UK-wide)
- Choose your nearest UK clinic
- Receive urine collection instructions
- Provide a urine sample
- Sample sent to the laboratory
- Results are issued once analysis is complete
Home or hotel collection (+£60, UK-wide)
- Urine collection kit provided
- Sample collected at home or hotel
- Sample returned for laboratory analysis
Your results explained
Low steroid metabolites
- Reduced excretion of steroid metabolites
- May indicate adrenal underactivity or impaired steroid production
Normal steroid profile
- Metabolite levels within reference ranges
- Suggests balanced adrenal hormone production and metabolism
High steroid metabolites
- Increased excretion of steroid metabolites
- May indicate adrenal overactivity, excess cortisol production, or altered metabolism
Interpretation depends on specific metabolites measured and clinical context.
How It Works
Simple steps to get your results
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Book Online
Choose your test online and book in seconds. Select your preferred clinic location or home visit option.
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Visit or Test at Home
Attend one of our UK or London clinics, arrange a home nurse visit, or use a finger-prick kit where available.
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Get Your Results
Your sample is analysed by accredited UK laboratories, with secure results delivered directly to you.
Take control of your health with London Blood Tests
WhatsApp UsHow to Prepare for Your Test
Follow these guidelines for accurate results
Sample Timing
Where possible, attend your blood test between 7am and 12pm. Please wait until any short-term illness or infection has fully resolved before testing. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.
Fasting & Hydration
Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours before your appointment and drink water only. Stay well hydrated, as this helps with sample collection and accuracy.
Medications & Supplements
Continue prescribed medications unless advised otherwise by your clinician. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results. If you are unsure about any medication or supplement, please let us know before your appointment.
Hormones & Menstrual Cycle
For hormone-related tests, timing within your menstrual cycle may be important. If relevant, follow any specific guidance provided on your test page.
If you have any questions or special circumstances, our team is happy to advise before your appointment.
Frequently Asked Questions
Steroid hormone metabolites mainly from adrenal hormones.
It provides different information, reflecting metabolism over time.
This depends on the laboratory protocol.
Yes, steroid medications can influence findings.
Yes, it is commonly used in adrenal investigations.
Chronic stress can influence steroid hormone output.
It may be used in follow-up assessments.
No, it supports diagnosis alongside other tests.
No, instructions are straightforward.
It indicates altered steroid hormone metabolism and supports further endocrine evaluation.
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